3 completed, 2 unknown, 1 recruiting, 1 withdrawn. 7 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 3, Unknown 2, Recruiting 1, Withdrawn 1 |
| Phase 2 | 4 | Unknown 2, Completed 1, Recruiting 1 |
Follow Soft-tissue Sarcoma: new trials by email Literature Review of Soft-tissue Sarcoma trials Research Report on Soft-tissue Sarcoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies Spedox-6, Pegfilgrastim, Filgrastim - Soft-tissue Sarcoma, Triple Negative Breast Cancer | Phase 1 / Phase 2 | Recruiting | University of California, Irvine | 67 | 2025-04-30 | 2026-07-17 |
| Phase I Study Compound 451238 and Radiotherapy in Soft-tissue Sarcoma Compound 451238 - Soft-tissue Sarcoma | Phase 1 / Phase 2 | Completed | Royal Marsden NHS Foundation Trust | 12 | 2018-11-05 | 2026-03-02 |
| A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors Phase 1 : Regorafenib, Phase 1 : Avelumab, Phase 2 : Regorafenib - Colorectal Cancer Not MSI-H or MMR-deficient, GIST | Phase 1 / Phase 2 | Unknown | Institut Bergonié | 747 | 2018-05-04 | 2023-03-03 |
| Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) Used for Mild Hyperthermia Magnetic Resonance-guided High-Intensity Focused Ultrasound - Healthy Participants, Pelvic Neoplasms | Phase 1 | Withdrawn | Washington University School of Medicine | 2017-09-30 | 2017-10-06 | |
| A Study of Olaparib With Concomitant Radiotherapy in Locally Advanced/Unresectable Soft-tissue Sarcoma Olaparib, Concomitant Radiotherapy - Soft-tissue Sarcoma | Phase 1 | Completed | Institut Bergonié | 41 | 2016-01-01 | 2026-02-25 |
| A Study of Metronomic CP and JX-594 in Patients With Advanced Breast Cancer and Advanced Soft-tissue Sarcoma (METROmaJX) Cyclophosphamide and JX-594 dose escalation, Cyclophosphamide and JX-594, Cyclophosphamide - Solid Tumors, Soft-tissue Sarcoma | Phase 1 / Phase 2 | Unknown | Institut Bergonié | 197 | 2015-09-18 | 2022-02-02 |
| Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma Pazopanib, GSK1120212 - Solid Tumors, Thyroid Cancer | Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 89 | 2011-10-01 | 2018-08-29 |
Sarcoma (7) · Carcinoma, Non-Small-Cell Lung (2) · Thyroid Neoplasms (2) · Triple Negative Breast Neoplasms (2) · Uterine Cervical Neoplasms (2) · Biliary Tract Neoplasms (1) · Breast Neoplasms (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Renal Cell (1) · Carcinoma, Transitional Cell (1) · Cholangiocarcinoma (1) · Gastro-enteropancreatic neuroendocrine tumor (1) · Mesothelioma, Malignant (1) · Neoplasm Metastasis (1) · Ovarian Neoplasms (1)
Neoplasms (7) · Neoplasms by Histologic Type (7) · Neoplasms, Connective and Soft Tissue (7) · Neoplasms by Site (5) · Breast Diseases (3) · Endocrine Gland Neoplasms (3) · Endocrine System Diseases (3) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Skin Diseases (3) · Skin and Connective Tissue Diseases (3) · Urogenital Diseases (3) · Urogenital Neoplasms (3) · Adenocarcinoma (2) · Breast Neoplasms (2)
Clinical Trials, Phase II as Topic (1) · Cyclophosphamide (1) · Filgrastim (1) · avelumab (1) · olaparib (1) · pazopanib (1) · pegfilgrastim (1) · regorafenib (1) · trametinib (1)
Institut Bergonié (3) · Royal Marsden NHS Foundation Trust (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1) · University of California, Irvine (1) · Washington University School of Medicine (1)
France (3) · United States (2) · United Kingdom (1)
Michael Altman, Ph.D. (1) · Nilo Azad, MD (1) · Shane Zaidi (1) · Warren Chow, MD (1)
PMID 32827353, PMID 34965951, PMID 34998048, PMID 39894354, PMID 40204996, PMID 40579407
2014 (1), 2015 (1), 2016 (1), 2017 (1)