11 completed, 2 unknown, 1 active not recruiting, 1 not yet recruiting. 9 Not applicable, 4 Phase 1, 2 Phase 4, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 8, Unknown 1 |
| Phase 1 | 4 | Active not recruiting 1, Completed 1, Not yet recruiting 1, Unknown 1 |
| Phase 4 | 2 | Completed 1, Withdrawn 1 |
| Early Phase 1 | 1 | Completed 1 |
Follow Skin Irritation: new trials by email Literature Review of Skin Irritation trials Research Report on Skin Irritation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety of Topical Exosome-Containing Liquid in Healthy Volunteers Exosome-Containing Liquid, Vehicle Liquid - Skin Irritation, Healthy Volunteers | Phase 1 | Active not recruiting | West Kazakhstan Marat Ospanov Medical University | 10 | 2026-09-25 | 2026-10-09 |
| Safety of Topical Exosome-Containing Liquid in Healthy Volunteers for Future Surgical Wound Use Exosome-Containing Liquid, Vehicle Liquid - Healthy Volunteers (HV), Skin Irritation | Phase 1 | Not yet recruiting | West Kazakhstan Marat Ospanov Medical University | 10 | 2026-09-01 | 2026-07-16 |
| Apple Peptide Complex for Post-Surgical and Aesthetic Skin Recovery Apple Peptide Complex Post-Aesthetic Care Protocol - Skin Barrier to Water Loss, Skin Health | Not applicable | Completed | Grow Out Oils Clinical Aromatherapy Company | 50 | 2021-01-20 | 2026-09-08 |
| HRIPT Study to Evaluate the Irritation and Allergenic Potential of Medical-grade Norway Spruce (Picea Abies) Resin Salve (Abilar) Abilar® Resin Salve - Skin Irritation, Skin Sensitization | Not applicable | Completed | Repolar Pharmaceuticals Oy | 215 | 2019-10-16 | 2025-02-06 |
| A Skin Irritation Assessment of Once-Weekly Corplex™ Donepezil Transdermal Delivery System Donepezil TDS, Vehicle TDS - Skin Irritation, Sensitization | Phase 1 | Completed | Corium, Inc. | 256 | 2017-11-14 | 2018-09-14 |
| Effect of Vitamin D After Application With Valchlor 4 placebo, 4 Vitamin D, Valchlor - Skin Irritation | Early Phase 1 | Completed | University Hospitals Cleveland Medical Center | 33 | 2016-11-17 | 2021-12-23 |
| Local Skin Safety Study of a Topical Pain Relief Spray Containing a Combination of Diclofenac, Methyl Salicylate, and Menthol Topical Spray, Topical Gel, Saline - Skin Irritation | Phase 4 | Withdrawn | GlaxoSmithKline | 2016-03-01 | 2017-09-12 | |
| Evaluation of Effectiveness and Mildness of Whole-natural Hand-wash Formulations MC Hand Soap, Tap water - Hand Hygiene, Skin Irritation | Not applicable | Unknown | Mother's Choice Ltd | 100 | 2016-01-01 | 2016-01-01 |
| A 21-Day Topical Safety Study of Diltiazem Hydrochloride Using a Cumulative Irritant Patch Test Design Diltiazem Hydrochloride 2% Cream, Vehicle Cream, 0.1% solution o sodium lauryl sulfate (SLS) - Skin Irritation | Phase 1 | Unknown | Ventrus Biosciences, Inc | 30 | 2013-03-01 | 2013-08-21 |
| Repeat Insult Patch Test of Skin Irritation/Sensitization for Cetaphil Daily Facial Cleanser Cetaphil Daily Facial Cleanser - Skin Irritation | Not applicable | Completed | Galderma R&D | 200 | 2012-12-01 | 2022-07-29 |
| Repeat Insult Patch Test of Skin Irritation/Sensitization for Cetaphil Dermacontrol Oil Control Moisturizer SPF 30 Cetaphil DermaControl Oil Control Moisturizer SPF 30 - Skin Irritation | Not applicable | Completed | Galderma R&D | 100 | 2012-12-01 | 2022-07-29 |
| Patch Test Skin Irritation/Sensitization of Cetaphil Restoraderm Skin Restoring Body Wash Cetaphil Restoraderm Skin Restoring Body Wash - Skin Irritation | Not applicable | Completed | Galderma R&D | 100 | 2012-12-01 | 2022-07-29 |
| Patch Test Skin Irritation/Sensitization of Cetaphil Daily Facial Moisturizer SPF 50 Cetaphil Daily Facial Moisturizer SPF 50 - Skin Irritation | Not applicable | Completed | Galderma R&D | 100 | 2012-12-01 | 2022-07-29 |
| Efficacy and Safety of Biocellulose Sheet Containing Anti-hyperpigmentation Agent ("Biocellulose Mask", "Farhorm®") in Patients Receiving Laser Treatment "Biocellulose Mask", Farhorm®" - Skin Pigmentation, Skin Irritation | Not applicable | Completed | Chulalongkorn University | 30 | 2012-09-01 | 2015-03-11 |
| Cetaphil® Daily Facial Moisturizer With Sunscreen SPF 50+ - Human Repeat Insult Patch Test Facial Moisturizer with SPF 50+ - Skin Irritation | Phase 4 | Completed | Galderma R&D | 128 | 2008-03-01 | 2022-08-01 |
| Repeat Insult Patch Test for Daily Advance Cetaphil Moisturizing Lotion Cetaphil Moisturizing Lotion Daily Advance - Skin Irritation | Not applicable | Completed | Galderma R&D | 146 | 2006-08-01 | 2022-07-29 |
Hyperpigmentation (1) · Lymphatic Abnormalities (1) · Pigmentation Disorders (1) · Skin Abnormalities (1) · Striae Distensae (1)
Pathological Conditions, Signs and Symptoms (2) · Skin Diseases (2) · Skin and Connective Tissue Diseases (2) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Hemic and Lymphatic Diseases (1) · Lymphatic Diseases (1) · Pathologic Processes (1) · Pigmentation Disorders (1) · Signs and Symptoms (1) · Skin Manifestations (1)
Sodium Chloride (2) · Amines (1) · Cholecalciferol (1) · Diltiazem (1) · Fluid Therapy (1) · Gels (1) · Mechlorethamine (1)
Galderma R&D (6) · West Kazakhstan Marat Ospanov Medical University (2) · Chulalongkorn University (1) · Corium, Inc. (1) · GlaxoSmithKline (1) · Grow Out Oils Clinical Aromatherapy Company (1) · Mother's Choice Ltd (1) · Repolar Pharmaceuticals Oy (1) · University Hospitals Cleveland Medical Center (1) · Ventrus Biosciences, Inc (1)
United States (9) · Kazakhstan (2) · Israel (1) · Thailand (1) · United Kingdom (1)
Mayya Tastene, MD (4) · Allon Moses, MD (1) · Danielle Armas, MD, CPI (1) · Dr. Lane Rolling MD, Virologist, Epidemiologist, (1) · James H Herndon, MD, FAAD (1) · Kurt Lu, MD (1) · Laura Sterling, MD, MPH (1) · Ronald Gottschalk, MD (1) · Shanna Bynes Bradford, Master Aromatherapy (1) · Vaeling Miller (1)
PMID 19043850, PMID 28805671, PMID 36692020, PMID 4658681
U01AR064144 (1)