11 completed, 2 active not recruiting, 2 unknown, 1 withdrawn. 9 Phase 2, 4 Phase 3, 2 Not applicable, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 8, Unknown 1 |
| Phase 3 | 4 | Active not recruiting 2, Completed 1, Unknown 1 |
| Not applicable | 2 | Completed 1, Withdrawn 1 |
| Early Phase 1 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Triamcinolone Acetonide Injections in Primary Cutaneous Lymphoma Plaques With a Novel Needle-free Drug-delivery System. Med-Jet Injector, Triamcinolone Acetonide, Bexarotene 1% Top Gel - Mycosis Fungoides of Skin (Diagnosis), Cutaneous T-cell Lymphoma | Not applicable | Withdrawn | Case Comprehensive Cancer Center | 2022-04-01 | 2025-06-12 | |
| Deep Phenotyping of Cutaneous T Cell Lymphoma, Type Mycosis Fungoides Chlormethine - Mycosis Fungoides | Not applicable | Completed | Centre for Human Drug Research, Netherlands | 32 | 2021-12-07 | 2023-01-25 |
| Valchlor in the Treatment of Lichen Planopilaris Mechlorethamine 0.016% Top Gel - Lichen Planopilaris | Phase 2 | Completed | Mayo Clinic | 12 | 2018-04-01 | 2021-01-28 |
| Mechlorethamine Induced Contact Dermatitis Avoidance Study Triamcinolone, Valchlor 0.016 % Topical Gel - Cutaneous T-cell Lymphoma, Cutaneous T-cell Lymphoma Stage I | Phase 2 | Completed | Rochester Skin Lymphoma Medical Group, PLLC | 28 | 2017-12-13 | 2026-09-04 |
| Effect of Vitamin D After Application With Valchlor 4 placebo, 4 Vitamin D, Valchlor - Skin Irritation | Early Phase 1 | Completed | University Hospitals Cleveland Medical Center | 33 | 2016-11-17 | 2021-12-23 |
| Combination Chemotherapy Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or High-Risk Primary Refractory Hodgkin Lymphoma cyclophosphamide, cyclosporine, fludarabine phosphate - Lymphoma | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 25 | 2007-11-13 | 2023-09-28 |
| Chemotherapy With Low-Dose Radiation for Pediatric Hodgkin Lymphoma Adriamycin®, Vinblastine, Nitrogen Mustard - Hodgkin's Lymphoma | Phase 2 | Completed | St. Jude Children's Research Hospital | 81 | 2006-07-20 | 2023-09-22 |
| Safety and Efficacy of Nitrogen Mustard in Treatment of Mycosis Fungoides mechlorethamine-MCH (nitrogen mustard) - Mycosis Fungoides | Phase 2 | Completed | Yaupon Therapeutics | 260 | 2006-05-01 | 2012-10-31 |
| Combination Chemotherapy in Treating Patients With Previously Untreated Advanced Hodgkin's Lymphoma bleomycin sulfate, ABVD regimen, Stanford V regimen - Lymphoma | Phase 3 | Unknown | Mount Vernon Cancer Centre at Mount Vernon Hospital | 850 | 2001-10-01 | 2013-09-20 |
| Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Hodgkin's Lymphoma Doxorubicin, Bleomycin, Vinblastine - Lymphoma | Phase 3 | Completed | Eastern Cooperative Oncology Group | 854 | 1999-06-17 | 2023-06-29 |
| Combination Chemotherapy in Treating Patients With Hodgkin's Disease and HIV Infection bleomycin sulfate, filgrastim, Stanford V regimen - Lymphoma | Phase 2 | Unknown | Centro di Riferimento Oncologico - Aviano | 30 | 1997-05-01 | 2013-09-20 |
| Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Early-Stage Hodgkin's Disease bleomycin sulfate, Stanford V regimen, doxorubicin hydrochloride - Lymphoma | Phase 2 | Completed | Stanford University | 1995-04-01 | 2013-05-15 | |
| Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Previously Untreated Stage I or Stage II Hodgkin's Lymphoma bleomycin sulfate, doxorubicin hydrochloride, mechlorethamine hydrochloride - Lymphoma | Phase 3 | Active not recruiting | European Organisation for Research and Treatment of Cancer - EORTC | 1158 | 1993-09-01 | 2025-08-05 |
| RT or No RT Following Chemotherapy in Treating Patients With Stage III/IV Hodgkin's Disease bleomycin sulfate, doxorubicin hydrochloride, mechlorethamine hydrochloride - Lymphoma | Phase 3 | Active not recruiting | European Organisation for Research and Treatment of Cancer - EORTC | 615 | 1989-09-01 | 2025-08-05 |
| Combination Chemotherapy in Treating Patients With Advanced Hodgkin's Lymphoma Bleomycin sulfate, Stanford V regimen, Doxorubicin hydrochloride - Lymphoma | Phase 2 | Completed | Stanford University | 50 | 1989-04-01 | 2020-08-12 |
| Combination Chemotherapy in Treating Children With Astrocytomas and Primitive Neuroectodermal Tumors MOPP Regimen, Leucovorin Calcium, Mechlorethamine Hydrochloride - Brain and Central Nervous System Tumors | Phase 2 | Completed | M.D. Anderson Cancer Center | 4 | 1989-02-01 | 2013-02-18 |
Hodgkin Disease (9) · Lymphoma (8) · Lymphoma, T-Cell, Cutaneous (4) · Mycosis Fungoides (3) · Astrocytoma (1) · Central Nervous System Neoplasms (1) · Dermatitis, Contact (1) · Disease (1) · Lichen Planus (1) · Lymphoma, Follicular (1) · Lymphoma, Large-Cell, Anaplastic (1) · Lymphoma, Non-Hodgkin (1) · Lymphomatoid Papulosis (1) · Recurrence (1)
European Organisation for Research and Treatment of Cancer - EORTC (2) · Stanford University (2) · Case Comprehensive Cancer Center (1) · Centre for Human Drug Research, Netherlands (1) · Centro di Riferimento Oncologico - Aviano (1) · Eastern Cooperative Oncology Group (1) · M.D. Anderson Cancer Center (1) · Mayo Clinic (1) · Memorial Sloan Kettering Cancer Center (1) · Mount Vernon Cancer Centre at Mount Vernon Hospital (1) · Rochester Skin Lymphoma Medical Group, PLLC (1) · St. Jude Children's Research Hospital (1) · University Hospitals Cleveland Medical Center (1) · Yaupon Therapeutics (1)
United States (11) · Italy (2) · Netherlands (2) · Belgium (1) · Canada (1) · Egypt (1) · France (1) · Germany (1) · Poland (1) · Portugal (1) · Slovenia (1) · South Africa (1) · United Kingdom (1)
Sandra J. Horning, MD (3) · Brian Poligone, MD, PhD (1) · Christophe Ferme (1) · H. Eghbali, MD (1) · Jamie Flerlage, MD (1) · Jason Sluzevich, MD (1) · Joann Ater, MD (1) · John Raemaekers, MD, PhD (1) · Juliet Barker, MBBS (1) · Kevin Cooper, MD (1) · Kurt Lu, MD (1) · Miguel-Angel Perales, MD (1) · Peter J. Hoskin, MD (1) · Robert Rissmann, Prof. Dr. (1) · Stuart Lessin, M.D. (1)
PMID 15936157, PMID 17097834, PMID 17989384, PMID 19828373, PMID 23069814, PMID 23182987, PMID 23356491, PMID 23386127, PMID 25897153, PMID 34091453, PMID 35122614, PMID 35536441, PMID 36692020, PMID 37802679, PMID 7537796, PMID 8836420, PMID 9187443
P30CA016672 (1), U01AR064144 (1), U10CA021115 (1)