21 completed, 3 not yet recruiting, 2 active not recruiting, 2 recruiting. 20 Not applicable, 4 Phase 3, 2 Phase 1, 2 Phase 2, 1 Phase 4.
Follow Sexually Transmitted Infection: new trials by email Literature Review of Sexually Transmitted Infection trials Research Report on Sexually Transmitted Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans Integrated care - Opioid Use Disorder, HIV | Not applicable | Not yet recruiting | VA Office of Research and Development | 60 | 2028-04-03 | 2026-04-24 |
| PrEPwise Pilot Among Black Women in Eastern Virginia PrEPwise, Usual care - HIV Infections, Sexually Transmitted Infection | Not applicable | Not yet recruiting | Boston University | 108 | 2027-04-01 | 2026-02-11 |
| Duo: A Phase IIIb Individual-Level Randomized Controlled Trial of an Integrated Strategy HIV PrEP - choice of F/TDF, F/TAF, or CAB-LA, STI PEP - Doxycycline as Doxy-PEP, 3P mHealth package - HIV Infection, Sexually Transmitted Infection | Phase 3 | Not yet recruiting | HIV Prevention Trials Network | 400 | 2026-09-01 | 2026-06-22 |
| Characterization of Doxycycline Pharmacokinetics and Adherence Single-Dose PK Phase - DR Group, Single-Dose PK Phase - IR Group, Multi-Dose PK Phase - Daily Group - Sexually Transmitted Infection | Phase 1 | Enrolling by invitation | HIV Prevention Trials Network | 16 | 2026-08-27 | 2026-09-17 |
| Improving Maternal and Child Health Through Point-of-care STI Testing Point-of-care STI tests, Standard of care STI testing - Treponema Pallidum Infection, Chlamydia Trachomatis Infection | Not applicable | Recruiting | Emory University | 756 | 2026-08-11 | 2026-08-19 |
| Daily Doxycycline to Inform Sexually Transmitted Infection Prophylaxis Regimens Doxycycline - Sexually Transmitted Infection | Phase 4 | Completed | Emory University | 24 | 2024-09-13 | 2026-05-01 |
| Efficacy Trial on Meningococcal B Vaccine for Preventing Gonorrhea Infections 4CMenB vaccine, Placebo - Gonorrhea, Sexually Transmitted Infection | Phase 3 | Active not recruiting | Chinese University of Hong Kong | 150 | 2023-05-04 | 2026-03-19 |
| Evaluation of Multisite Sampling to Detect C. Trachomatis or N. Gonorrheae Compared With Vaginal Sampling in Women at Risk for Sexually Transmitted Infections Vaginal, Oral and anal sampling - Sexually Transmitted Infection | Not applicable | Completed | Centre Hospitalier Régional d'Orléans | 1500 | 2023-04-14 | 2024-11-18 |
| Investigating Point-of-care Diagnostics for Sexually Transmitted Infections and Antimicrobial Resistance in Primary Care in Zimbabwe Point-of-care STI testing - Sexually Transmitted Infection, Chlamydia | Not applicable | Completed | London School of Hygiene and Tropical Medicine | 1005 | 2023-01-12 | 2025-09-25 |
| Personalized Prevention for Couples: A 16-month Digital RCT Intervention LuvHub, Waitlist Control LuvHub - Hiv, HIV Infections | Not applicable | Completed | Florida International University | 778 | 2023-01-11 | 2025-09-17 |
| Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes (Philani Ndiphile) First antenatal care + test-of-cure, First antenatal care + week 30-34 gestation (no test-of-cure) - Sexually Transmitted Infection, HIV/AIDS | Not applicable | Completed | Foundation for Professional Development (Pty) Ltd | 2247 | 2021-03-29 | 2026-07-17 |
| Epidemiology of Sexually Transmitted Infections and Its iMpAcT on fEmale Infertility vaginal swab - Sexually Transmitted Infection | Recruiting | University of Luebeck | 533 | 2020-11-11 | 2026-04-30 | |
| User-friendly HIV Testing and Counseling Services HIV Infections, Sexually Transmitted Infection | Unknown | Institut de Recherche pour le Developpement | 3000 | 2020-10-19 | 2023-10-31 | |
| A Comprehensive HIV Prevention Package for South African Adolescent Girls and Young Women: IMARA SA IMARA-SA (intervention group), Health promotion control group - Sexually Transmitted Infection, Hiv | Not applicable | Completed | University of Illinois at Chicago | 61 | 2019-10-26 | 2025-08-22 |
| The People Like Us Evaluation Study People Like Us Online Video Series Intervention, Sexual Health Pamphlet (Standard of Care) - HIV/AIDS, Sexually Transmitted Infection | Not applicable | Completed | National University of Singapore | 300 | 2019-10-13 | 2021-09-01 |
| Expanding PrEP By Embedding Unannounced SNAPS Navigators in High STI Testing Clinical Sites SNAPS intervention - Hiv, Sexually Transmitted Infection | Not applicable | Completed | NYU Langone Health | 200 | 2019-07-22 | 2023-02-09 |
| Technology-Based Intervention for Reducing Sexually Transmitted Infections and Substance Use During Pregnancy Health Check-up for Expectant Moms, Time, attention, and information-matched control - Sexually Transmitted Infection, Alcohol Use Complicating the Puerperium | Not applicable | Completed | University of Michigan | 180 | 2019-04-16 | 2025-05-20 |
| Use of a Rapid Test for Gonorrhea & Chlamydia for Women Presenting With Possible Sexually Transmitted Infections Cepheid Xpert CT/NG Rapid Turnaround Test, Polymerase chain reaction (PCR) - Sexually Transmitted Infection, Gonorrhea Female | Not applicable | Terminated | University of Maryland, Baltimore | 64 | 2018-09-24 | 2023-08-31 |
| A Novel Regimen to Prevent Malaria and STI in Pregnant Women With HIV Azithromycin/TMPS, Placebo/TMPS - HIV, Pregnancy Malaria | Phase 2 | Completed | University of Alabama at Birmingham | 308 | 2018-03-07 | 2023-11-27 |
| GPS: Adaptation Trial of an HIV Prevention Counselling Program for HIV-positive and HIV-negative Gay and Bisexual Men GPS program - HIV/AIDS, Sexually Transmitted Infection | Not applicable | Completed | Toronto Metropolitan University | 50 | 2017-09-01 | 2020-03-10 |
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Sexually Transmitted Diseases (32) · Acquired Immunodeficiency Syndrome (7) · Gonorrhea (5) · HIV Infections (5) · Chlamydia Infections (3) · Sexual Behavior (3) · Syphilis (3) · Health Behavior (2) · Hepatitis B (2) · Hepatitis C (2) · Substance-Related Disorders (2) · Anxiety Disorders (1) · Bacterial Infections (1) · Coitus (1) · Criminal Behavior (1)
Communicable Diseases (32) · Disease Attributes (32) · Genital Diseases (32) · Infections (32) · Pathologic Processes (32) · Pathological Conditions, Signs and Symptoms (32) · Urogenital Diseases (32) · Blood-Borne Infections (11) · RNA Virus Infections (11) · Virus Diseases (11) · Immune System Diseases (10) · Immunologic Deficiency Syndromes (10) · Lentivirus Infections (10) · Retroviridae Infections (10) · Sexually Transmitted Diseases, Viral (10)
Standard of Care (2) · 4CMenB vaccine (1) · Delivery of Health Care, Integrated (1) · Doxycycline (1) · Fluconazole (1) · Health Promotion (1) · Motivational Interviewing (1) · Polymerase Chain Reaction (1) · Time (1) · Trimethoprim, Sulfamethoxazole Drug Combination (1)
Boston Medical Center (2) · Emory University (2) · HIV Prevention Trials Network (2) · University of Washington (2) · Assistance Publique Hopitaux De Marseille (1) · Boston University (1) · Carnegie Mellon University (1) · Centre Hospitalier Régional d'Orléans (1) · Chinese University of Hong Kong (1) · Florida International University (1) · Foundation for Professional Development (Pty) Ltd (1) · Institut de Recherche pour le Developpement (1) · London School of Hygiene and Tropical Medicine (1) · NYU Langone Health (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1)
United States (18) · Brazil (2) · France (2) · South Africa (2) · Argentina (1) · Canada (1) · Germany (1) · Hong Kong (1) · India (1) · Kenya (1) · Peru (1) · Singapore (1) · Thailand (1) · Uganda (1) · Zimbabwe (1)
Andrew Medina-Marino, PhD, MPH (1) · Audun J Lier, MD (1) · Colleen Kelley, MD, MPH (1) · Edward Bernstein, MD (1) · Geri R Donenberg, PhD (1) · Golfo Tzilos Wernette (1) · Gonzague Jourdain, MD, PhD (1) · Jane D Champion, PhD (1) · Jason W Mitchell, PhD (1) · Jeffrey Klausner, MD, MPH (1) · Jodie A Dionne-Odom, MD (1) · Jorge Gallardo-Cartagena, MD (1) · Julie Downs, PhD (1)
PMID 15279915, PMID 17602298, PMID 18302016, PMID 18516681, PMID 18565433, PMID 19509119, PMID 19736331, PMID 20422289, PMID 21667142, PMID 21809149, PMID 21969362, PMID 22108900, PMID 22121303, PMID 22199409, PMID 22720764, PMID 22921136, PMID 23054169, PMID 23111547, PMID 23412948, PMID 23606774, PMID 23828448, PMID 23867137, PMID 24319545, PMID 24322060, PMID 24465089, PMID 24704179, PMID 24986217, PMID 25225369, PMID 25323784, PMID 25366931, PMID 26017632, PMID 26149165, PMID 26213527, PMID 26462492, PMID 26951879, PMID 27079291, PMID 27397946, PMID 32269026, PMID 34011583, PMID 34351867, PMID 35461085, PMID 35522470, PMID 35610666, PMID 36151975, PMID 36962830, PMID 37022682, PMID 37080628, PMID 39324693, PMID 41085955, PMID 41240948
UM1AI068619 (2), 1IK2CX002822-01A1 (1), K01MH136935 (1), R01AI149339 (1), R01DA019180 (1), R01DA044522 (1), R01HD093611 (1), R01MD020754 (1), R01MH089129 (1), R01MH109337 (1), R01MH126880 (1), R34MH094163 (1)