7 completed, 3 unknown, 2 not yet recruiting. 12 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Completed 7, Unknown 3, Not yet recruiting 2 |
Follow Severe Pneumonia: new trials by email Literature Review of Severe Pneumonia trials Research Report on Severe Pneumonia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Feasibility and Preliminary Efficacy of a Child Life-Based Breathing Exercise Program for Children Recovering From Severe Pneumonia: A Pilot Randomized Controlled Trial routine health education + a Child Life-Based Breathing Exercise Program, routine health education - Severe Pneumonia | Not applicable | Not yet recruiting | Children's Hospital of Fudan University | 30 | 2026-06-01 | 2026-05-18 |
| Enhancing Pediatric Acute Care Through Adaptive E-Learning and In-Person Skills Practice in Tanzania Rhapsode Capable™ Platform (Intervention Group), Paper-based ISP (Control Group) - Newborn Resuscitation, Severe Malnutrition | Not applicable | Not yet recruiting | Stanford University | 100 | 2025-01-06 | 2024-10-10 |
| Species-specific Bacterial Detector for Fast Pathogen Diagnosis of Severe Pneumonia results of SSBD are used to guide antibiotics adjustment - Severe Pneumonia | Not applicable | Unknown | Chinese Medical Association | 256 | 2024-11-01 | 2024-10-26 |
| Fiberoptic Bronchoscopy in Severe Ventilator-associated Pneumonia Other (Conventional Therapy), Fiberoptic Bronchoscopy - Ventilator-Associated Pneumonia, Severe Pneumonia | Not applicable | Completed | Benha University | 100 | 2023-12-15 | 2025-09-02 |
| Treatment of COVID-19 Positive/Negative Bangladeshi Adults With Severe Respiratory Complaints by a Locally Made bCPAP: Feasibility Study Adult bubble CPAP oxygen therapy device - Severe Pneumonia, Acute Respiratory Distress Syndrome | Not applicable | Completed | International Centre for Diarrhoeal Disease Research, Bangladesh | 20 | 2021-10-08 | 2022-08-25 |
| Early Identification and Severity Prediction of Acute Respiratory Infectious Disease mNGS, Multiplex PCR - Acute Respiratory Infection, Severe Pneumonia | Not applicable | Unknown | Huashan Hospital | 440 | 2021-04-04 | 2022-05-12 |
| Feasibility and Acceptability Followed by Effectiveness of bCPAP for Treatment of Children Aged 1-59 Months With Severe Pneumonia in Ethiopia Bubble CPAP, Low flow oxygen - Severe Pneumonia | Not applicable | Completed | International Centre for Diarrhoeal Disease Research, Bangladesh | 1240 | 2019-09-02 | 2023-08-07 |
| Impact of Pulse Oximetry on Hospital Referral Acceptance in Children Under 5 With Severe Pneumonia Pulse Oximetry - Severe Pneumonia, Hypoxemia | Not applicable | Completed | Aga Khan University | 543 | 2019-08-01 | 2022-03-31 |
| The Effect of Prone Position Drainage on the Efficacy of Severe Pneumonia，a Multicenter Randomized Controlled Trial Placed in prone position for at least 16 consecutive hours a day. - Severe Pneumonia | Not applicable | Unknown | Xiangya Hospital of Central South University | 500 | 2019-04-01 | 2019-03-26 |
| Impact of Systematic Early Tuberculosis Detection Using Xpert MTB/RIF Ultra in Children With Severe Pneumonia in High Tuberculosis Burden Countries (TB-Speed Pneumonia) Xpert MTB/RIF Ultra (Ultra) - Tuberculosis, Severe Pneumonia | Not applicable | Completed | Institut National de la Santé Et de la Recherche Médicale, France | 2570 | 2019-03-20 | 2025-12-04 |
| Community Case Management of the Severe Pneumonia With Oral Amoxicillin in Children 2-59 Months of Age Amoxicillin, Referral to Health facility - Severe Pneumonia | Not applicable | Completed | Aga Khan University | 4070 | 2008-02-01 | 2017-05-22 |
| Randomized Controlled Trial (RCT) in Children With Severe Pneumonia Day-care treatment vs. hospital care - Severe Pneumonia | Not applicable | Completed | International Centre for Diarrhoeal Disease Research, Bangladesh | 368 | 2005-12-01 | 2011-07-12 |
Pneumonia (12) · COVID-19 (2) · Hypoxia (2) · Cephalopelvic Disproportion (1) · Child Nutrition Disorders (1) · Critical Illness (1) · Dehydration (1) · Disease (1) · Malaria (1) · Malnutrition (1) · Pneumonia, Ventilator-Associated (1) · Respiratory Aspiration (1) · Respiratory Distress Syndrome (1) · Respiratory Tract Infections (1) · Tuberculosis (1)
Infections (12) · Lung Diseases (12) · Respiratory Tract Diseases (12) · Respiratory Tract Infections (11) · Pathological Conditions, Signs and Symptoms (6) · Pathologic Processes (4) · Coronaviridae Infections (2) · Coronavirus Infections (2) · Nidovirales Infections (2) · Pneumonia, Viral (2) · RNA Virus Infections (2) · Respiration Disorders (2) · Signs and Symptoms (2) · Signs and Symptoms, Respiratory (2) · Virus Diseases (2)
Amoxicillin (1) · Control Groups (1) · Oximetry (1) · Prone Position (1)
International Centre for Diarrhoeal Disease Research, Bangladesh (3) · Aga Khan University (2) · Benha University (1) · Children's Hospital of Fudan University (1) · Chinese Medical Association (1) · Huashan Hospital (1) · Institut National de la Santé Et de la Recherche Médicale, France (1) · Stanford University (1) · Xiangya Hospital of Central South University (1)
Bangladesh (3) · China (3) · Pakistan (2) · Cambodia (1) · Cameroon (1) · Côte d’Ivoire (1) · Egypt (1) · Mozambique (1) · Tanzania (1) · Uganda (1) · Zambia (1)
Adolfine Hokororo, MD (1) · Eric Wobudeya, MD, PhD (1) · Fatima Mir, FCPS (1) · Hasan Ashraf, MD (1) · Maryline Bonnet, MD, PhD (1) · Mohammod J Chisti (1) · Mohammod Jobayer Chisti, PhD (1) · Olivier Marcy, MD, PhD (1) · Peter A Meaney, MD MPH (1) · Pinhua Pan, Doctor (1) · Wenhong Zhang, Prof (1) · Wenkui Yu, MD (1) · Zulfiqar ZB Bhutta, MBBS, PhD (1)
PMID 20855397, PMID 22285055, PMID 22842561, PMID 26296950, PMID 32853411, PMID 33743621, PMID 34535473, PMID 35858876, PMID 36395782, PMID 36579494, PMID 38522443
R21TW012612 (1)