5 terminated. 5 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Terminated 5 |
| Phase 1 | 1 | Terminated 1 |
Follow Severe Aplastic Anemia: new trials by email Literature Review of Severe Aplastic Anemia trials Research Report on Severe Aplastic Anemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Reduced Dose of Cyclophosphamide Combined With Standard Immunosuppressive Therapy to Treat Severe Aplastic Anemia Reduced dose of cyclophosphamide combined with standard immunosuppressive therapy - Severe Aplastic Anemia, Cyclophosphamide Reduced-dose | Phase 2 | Terminated | Institute of Hematology & Blood Diseases Hospital, China | 14 | 2024-11-01 | 2026-11-04 |
| Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer Cyclophosphamide, Fludarabine Phosphate, Laboratory Biomarker Analysis - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Leukemia in Remission | Phase 2 | Terminated | Roswell Park Cancer Institute | 31 | 2017-12-07 | 2025-07-04 |
| Bone Marrow Transplant Trial for Patients With Refractory Severe Aplastic Anemia Bone Marrow Transplant - Severe Aplastic Anemia | Phase 2 | Terminated | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 4 | 2011-06-01 | 2016-10-13 |
| Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerous Inherited Disorders Allogeneic Bone Marrow Transplantation, Cyclophosphamide, Fludarabine Phosphate - Immunodeficiency Syndrome, Severe Aplastic Anemia | Phase 2 | Terminated | Fred Hutchinson Cancer Center | 14 | 2006-05-24 | 2021-01-26 |
| Antibody Conditioning Regimen For Allogeneic Donor Stem Cell Transplantation Of Patients With Fanconi Anemia CAMPATH-1H, Anti-CD45, Fludarabine - Fanconi Anemia, Severe Aplastic Anemia | Phase 1 / Phase 2 | Terminated | Baylor College of Medicine | 5 | 2001-07-01 | 2018-05-24 |
Anemia, Aplastic (5) · Immunologic Deficiency Syndromes (2) · Anemia, Diamond-Blackfan (1) · Anemia, Sickle Cell (1) · Congenital amegakaryocytic thrombocytopenia (1) · Fanconi Anemia (1) · Genetic Diseases, Inborn (1) · Granulomatous Disease, Chronic (1) · Hemoglobinuria, Paroxysmal (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Leukemia, Myeloid, Accelerated Phase (1) · Leukemia, Myeloid, Acute (1) · Leukemia, Myeloid, Chronic-Phase (1) · Leukemia, Myelomonocytic, Chronic (1)
Anemia (5) · Bone Marrow Diseases (5) · Bone Marrow Failure Disorders (5) · Hematologic Diseases (5) · Hemic and Lymphatic Diseases (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Anemia, Hypoplastic, Congenital (2) · Congenital Bone Marrow Failure Syndromes (2) · Genetic Diseases, Inborn (2) · Immune System Diseases (2) · Metabolic Diseases (2) · Nutritional and Metabolic Diseases (2) · Anemia, Hemolytic (1) · Anemia, Hemolytic, Congenital (1) · Blood Coagulation Disorders (1)
Cyclophosphamide (2) · Whole-Body Irradiation (2) · fludarabine phosphate (2) · Alemtuzumab (1) · Bone Marrow Transplantation (1) · Mycophenolic Acid (1) · Peripheral Blood Stem Cell Transplantation (1) · Sirolimus (1) · Tacrolimus (1) · fludarabine (1)
Baylor College of Medicine (1) · Fred Hutchinson Cancer Center (1) · Institute of Hematology & Blood Diseases Hospital, China (1) · Roswell Park Cancer Institute (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1)
United States (4) · China (1)
Amy Dezern, MD (1) · Kanwaldeep Mallhi (1) · Malcolm Brenner, M.B., Ph.D., (1) · Philip McCarthy, MD (1) · Robert A Brodsky, MD (1)
P01HL122173 (1), P30CA015704 (1)