6 completed, 1 not yet recruiting, 1 suspended, 1 unknown. 9 Phase 1, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 9 | Completed 6, Not yet recruiting 1, Suspended 1, Unknown 1 |
| Phase 2 | 7 | Completed 4, Not yet recruiting 1, Suspended 1, Unknown 1 |
Follow Sensorineural Hearing Loss: new trials by email Literature Review of Sensorineural Hearing Loss trials Research Report on Sensorineural Hearing Loss
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| First In Human Randomised Trial of Rincell-1 in Adults With a Cochlear Implant Otic neural progenitors, cochlear implantation - Sensorineural Hearing Loss, Presbyacusis | Phase 1 / Phase 2 | Not yet recruiting | Rinri Therapeutics | 20 | 2027-09-01 | 2026-10-01 |
| Phase I/IIa Study Evaluating Safety and Efficacy of an Intratympanic Dose of PIPE-505 in Subjects With Hearing Loss PIPE-505, Placebo - Sensorineural Hearing Loss | Phase 1 / Phase 2 | Completed | Contineum Therapeutics | 28 | 2020-10-15 | 2025-04-01 |
| OTO-413 in Subjects With Speech-in-Noise Hearing Impairment OTO-413, Placebo - Sensorineural Hearing Loss | Phase 1 / Phase 2 | Completed | Otonomy, Inc. | 110 | 2019-10-01 | 2022-10-27 |
| FX-322 in Sensorineural Hearing Loss FX-322, Placebo - Sensorineural Hearing Loss | Phase 1 / Phase 2 | Completed | Frequency Therapeutics | 23 | 2018-07-03 | 2022-11-14 |
| Autologous Bone Marrow Harvest and Transplant for Sensorineural Hearing Loss Autologous Bone Marrow Infusion - Sensorineural Hearing Loss | Phase 1 / Phase 2 | Suspended | James Baumgartner, MD | 10 | 2015-10-01 | 2022-03-18 |
| Study to Determine the Safety, Tolerability, and Pharmacokinetic Profile of HPN-07 and HPN-07 Plus NAC HPN-07, NAC, Placebo - Hearing Loss, Sensorineural Hearing Loss | Phase 1 | Completed | Otologic Pharmaceutics, Inc. | 32 | 2014-10-01 | 2015-05-01 |
| Safety of Autologous Stem Cell Infusion for Children With Acquired Hearing Loss Autologous Stem Cells - Sensorineural Hearing Loss | Phase 1 | Completed | James Baumgartner, MD | 11 | 2013-01-01 | 2026-07-09 |
| Effectiveness of P02 Digital Hearing Aids Hearing Aids Evaluation - Hearing Loss, Bilateral, Sensorineural Hearing Loss | Phase 1 / Phase 2 | Unknown | Khon Kaen University | 100 | 2012-10-01 | 2014-04-21 |
| A Clinical Trial of Anakinra for Steroid-Resistant Autoimmune Inner Ear Disease Anakinra - Sensorineural Hearing Loss, Autoimmune Inner Ear Disease | Phase 1 / Phase 2 | Completed | Andrea Vambutas | 13 | 2011-06-01 | 2018-01-10 |
Hearing Loss, Sensorineural (9) · Hearing Loss (3) · Hearing Loss, Hidden (2) · Auditory neuropathy (1) · Deafness (1) · Hearing Loss, Bilateral (1) · Hearing Loss, Noise-Induced (1) · Hearing Loss, Sudden (1) · Meniere Disease (1) · Presbycusis (1) · Retrocochlear Diseases (1)
Ear Diseases (9) · Hearing Disorders (9) · Nervous System Diseases (9) · Neurologic Manifestations (9) · Otorhinolaryngologic Diseases (9) · Pathological Conditions, Signs and Symptoms (9) · Sensation Disorders (9) · Signs and Symptoms (9) · Hearing Loss (6) · Endolymphatic Hydrops (1) · Labyrinth Diseases (1)
Cell- and Tissue-Based Therapy (2) · Acetylcysteine (1) · Cochlear Implantation (1) · Interleukin 1 Receptor Antagonist Protein (1) · disufenton sodium (1)
James Baumgartner, MD (2) · Andrea Vambutas (1) · Contineum Therapeutics (1) · Frequency Therapeutics (1) · Khon Kaen University (1) · Otologic Pharmaceutics, Inc. (1) · Otonomy, Inc. (1) · Rinri Therapeutics (1)
United States (7) · Thailand (1) · United Kingdom (1)
James Baumgartner, MD (2) · Andrea Vambutas, MD (1) · Douglas Hartley (1) · George Atiee, MD (1) · Kwanchanok Yimtae, MD (1) · Stephen Huhn, MD (1) · Treva Tyson, MD (1)
PMID 25133431, PMID 34301203, PMID 42479273
R33DC011827 (1)