1 active not recruiting, 1 completed, 1 terminated. 2 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 1, Terminated 1 |
| Phase 2 | 1 | Active not recruiting 1 |
Follow Refractory Neoplasm: new trials by email Literature Review of Refractory Neoplasm trials Research Report on Refractory Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| 9-ING-41 in Pediatric Patients With Refractory Malignancies. 9-ING-41, Irinotecan, Temozolomide - Refractory Cancer, Refractory Neoplasm | Phase 1 | Terminated | Actuate Therapeutics Inc. | 40 | 2020-06-05 | 2025-07-17 |
| 9-ING-41 in Patients With Advanced Cancers 9-ING-41, Gemcitabine - 21 day cycle, Doxorubicin. - Cancer, Pancreatic Cancer | Phase 2 | Active not recruiting | Actuate Therapeutics Inc. | 350 | 2019-01-04 | 2026-04-03 |
| Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers Laboratory Biomarker Analysis, Metformin, Pharmacological Study - Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm | Phase 1 | Completed | M.D. Anderson Cancer Center | 31 | 2018-03-12 | 2023-10-04 |
Neoplasms (3) · Neoplasm Metastasis (2) · Bone Neoplasms (1) · Breast Neoplasms (1) · Colorectal Neoplasms (1) · Diffuse Intrinsic Pontine Glioma (1) · Glioma (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Kidney Neoplasms (1) · Leukemia-Lymphoma, Adult T-Cell (1) · Lung Neoplasms (1) · Lymphoma, Non-Hodgkin (1) · Meningioma (1) · Neuroblastoma (1) · Pancreatic Neoplasms (1)
Neoplasms by Histologic Type (2) · Neoplasms by Site (2) · Neoplasms, Germ Cell and Embryonal (2) · Neoplasms, Glandular and Epithelial (2) · Neoplasms, Nerve Tissue (2) · Neoplasms, Neuroepithelial (2) · Neoplastic Processes (2) · Nervous System Diseases (2) · Neuroectodermal Tumors (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Bone Diseases (1) · Brain Diseases (1) · Brain Neoplasms (1) · Brain Stem Neoplasms (1)
3-(5-fluorobenzofuran-3-yl)-4-(5-methyl-5H-(1,3)dioxolo(4,5-f)indol-7-yl)-pyrrole-2,5-dione (2) · Irinotecan (2) · Albumin-Bound Paclitaxel (1) · Carboplatin (1) · Cyclophosphamide (1) · Doxorubicin (1) · Gemcitabine (1) · Lomustine (1) · Metformin (1) · Paclitaxel (1) · Taxes (1) · Temozolomide (1) · Topotecan (1) · liposomal doxorubicin (1) · sapanisertib (1)
Actuate Therapeutics Inc. (2) · M.D. Anderson Cancer Center (1)
United States (3) · Belgium (1) · Canada (1) · France (1) · Netherlands (1) · Portugal (1) · Spain (1)
Vivek Subbiah (1)
PMID 24327518, PMID 27424289, PMID 28053024, PMID 28672195, PMID 29383130, PMID 29846250, PMID 31101621, PMID 31533931, PMID 31831767, PMID 31882719, PMID 30405781, PMID 30975030, PMID 31401903, PMID 31894292, PMID 35815408, PMID 38126764, PMID 41981308
P30CA016672 (1)