3 active not recruiting, 2 recruiting, 1 completed. 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Active not recruiting 3, Recruiting 2, Completed 1 |
Follow Recurrent Kidney Wilms Tumor: new trials by email Literature Review of Recurrent Kidney Wilms Tumor trials Research Report on Recurrent Kidney Wilms Tumor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor Biospecimen Collection, Computed Tomography, Echocardiography Test - Desmoplastic Small Round Cell Tumor, Osteosarcoma | Phase 2 | Recruiting | National Cancer Institute (NCI) | 55 | 2021-03-08 | 2026-10-28 |
| A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT Biopsy Procedure, Biospecimen Collection, Bone Scan - Anaplastic Kidney Wilms Tumor, Recurrent Kidney Wilms Tumor | Phase 2 | Recruiting | Children's Oncology Group | 256 | 2020-10-19 | 2026-08-25 |
| Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial Tipifarnib - Malignant Solid Neoplasm, Recurrent Adrenal Gland Pheochromocytoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 5 | 2020-10-13 | 2026-10-16 |
| Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial) Laboratory Biomarker Analysis, Palbociclib, Pharmacological Study - Advanced Malignant Solid Neoplasm, Recurrent Childhood Ependymoma | Phase 2 | Completed | National Cancer Institute (NCI) | 23 | 2018-08-13 | 2026-04-03 |
| Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial) Biospecimen Collection, Bone Marrow Aspiration and Biopsy, Bone Scan - Advanced Malignant Solid Neoplasm, Recurrent Ependymoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 9 | 2017-08-23 | 2026-06-17 |
| Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors Cabozantinib, Cabozantinib S-malate, Pharmacological Study - Adrenal Cortical Carcinoma, Alveolar Soft Part Sarcoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 109 | 2017-05-18 | 2026-08-28 |
Wilms Tumor (6) · Osteosarcoma (5) · Hepatoblastoma (4) · Rhabdomyosarcoma (4) · Sarcoma (4) · Ependymoma (3) · Glioma (3) · Histiocytosis, Langerhans-Cell (3) · Lymphoma, Non-Hodgkin (3) · Medulloblastoma (3) · Neuroblastoma (3) · Neuroectodermal Tumors, Primitive, Peripheral (3) · Rhabdoid Tumor (3) · Sarcoma, Ewing (3) · Central Nervous System Neoplasms (2)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Female Urogenital Diseases (6) · Female Urogenital Diseases and Pregnancy Complications (6) · Genetic Diseases, Inborn (6) · Kidney Diseases (6) · Kidney Neoplasms (6) · Male Urogenital Diseases (6) · Neoplasms (6) · Neoplasms by Histologic Type (6) · Neoplasms by Site (6) · Neoplasms, Complex and Mixed (6) · Neoplastic Syndromes, Hereditary (6) · Urogenital Diseases (6) · Urogenital Neoplasms (6) · Urologic Diseases (6)
Magnetic Resonance Spectroscopy (3) · Specimen Handling (3) · Biopsy (2) · Phantoms, Imaging (2) · X-Rays (2) · Carboplatin (1) · Cyclophosphamide (1) · Doxorubicin (1) · Etoposide (1) · Ifosfamide (1) · Irinotecan (1) · Nuclear Medicine Department, Hospital (1) · Radiation (1) · Radiotherapy (1) · Surgical Procedures, Operative (1)
National Cancer Institute (NCI) (5) · Children's Oncology Group (1)
United States (6) · Puerto Rico (4) · Australia (1) · Canada (1) · New Zealand (1) · Saudi Arabia (1)
Christine A Pratilas (1) · Damon R Reed (1) · James I Geller (1) · Katherine A Janeway (1) · Rajen Mody (1) · Srivandana Akshintala (1)
PMID 31401903, PMID 39298716, PMID 42131734, PMID 42853672
U10CA180886 (5), UM1CA228823 (1)