3 completed, 1 active not recruiting, 1 withdrawn. 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 1 | Completed 1 |
Follow Pyridoxine-dependent epilepsy: new trials by email Literature Review of Pyridoxine-dependent epilepsy trials Research Report on Pyridoxine-dependent epilepsy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation by a Vineland II Scale of Long-term Development of Children With Pyridoxine Dependent Epilepsy VINELAND II - Pyridoxine-Dependent Epilepsy | Completed | University Hospital, Angers | 30 | 2023-12-29 | 2026-08-10 | |
| Baby Detect : Genomic Newborn Screening Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1 | Completed | Centre Hospitalier Universitaire de Liege | 6824 | 2022-09-01 | 2025-08-12 | |
| Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer Pembrolizumab, Tadalafil - Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma | Phase 2 | Completed | University of California, San Diego | 7 | 2020-04-07 | 2026-02-12 |
| Early Check: Expanded Screening in Newborns Confirmatory Testing - Spinal Muscular Atrophy, Fragile X Syndrome | Active not recruiting | RTI International | 30000 | 2018-10-15 | 2026-07-01 | |
| Neurodevelopmental Outcome of Early Dietary Lysine Restriction in Pyridoxine Dependent Epilepsy Patients Lysine Restricted Diet, Pyridoxine - Pyridoxine Dependant Epilepsy | Withdrawn | University of British Columbia | 2013-04-01 | 2014-09-30 |
3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency (2) · Acidemia, isovaleric (2) · Anemia, Sickle Cell (2) · Argininosuccinic Aciduria (2) · Ataxia with vitamin E deficiency (2) · Basal ganglia disease, biotin-responsive (2) · Beta ketothiolase deficiency (2) · Biotinidase Deficiency (2) · Brown-Vialetto-Van Laere syndrome (2) · Carbamoyl-Phosphate Synthase I Deficiency Disease (2) · Carnitine palmitoyl transferase 1A deficiency (2) · Carnitine palmitoyl transferase 2 deficiency (2) · Carnitine-Acylcarnitine Translocase Deficiency (2) · Citrullinemia (2)
Digestive System Diseases (3) · Neoplasms by Histologic Type (3) · Neoplasms by Site (3) · Neoplasms, Glandular and Epithelial (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Abnormalities, Multiple (2) · Albinism (2) · Amino Acid Metabolism, Inborn Errors (2) · Anemia (2) · Anemia, Hemolytic (2) · Anemia, Hemolytic, Congenital (2) · Arrhythmias, Cardiac (2) · Avitaminosis (2) · Basal Ganglia Diseases (2)
Pyridoxine (1) · Tadalafil (1) · pembrolizumab (1)
Centre Hospitalier Universitaire de Liege (1) · RTI International (1) · University Hospital, Angers (1) · University of British Columbia (1) · University of California, San Diego (1)
United States (3) · Belgium (1) · Canada (1) · France (1) · Germany (1) · Netherlands (1) · Switzerland (1) · United Kingdom (1)
Clara van Karnebeek (1) · Curt Scharfe, MD, PhD (1) · Joseph Califano (1) · Laurent Servais (1) · Sylvia Stockler (1)
PMID 10519720, PMID 18762976, PMID 30043187, PMID 30671974, PMID 31315600, PMID 33200442, PMID 33748042, PMID 35142618