15 completed, 8 recruiting, 5 unknown, 4 not yet recruiting. 31 Not applicable, 2 Phase 1, 1 Early Phase 1, 1 Phase 2, 1 Phase 3.
Follow Prolonged Grief Disorder: new trials by email Literature Review of Prolonged Grief Disorder trials Research Report on Prolonged Grief Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mechanisms Underlying Late-Life Prolonged Grief Disorder Iyengar Yoga, Health Education Control, Waitlist Control to Crossover - Prolonged Grief Disorder | Not applicable | Not yet recruiting | Medical College of Wisconsin | 126 | 2027-01-01 | 2026-10-09 |
| Perioperative Dexmedetomidine to Reduce Post-procedure Grief Following Second-trimester Dilation and Evacuation Dexmedetomidine (IV) 0.5 mcg/kg, Placebo - Abortion, Stillbirth | Phase 2 / Phase 3 | Withdrawn | Stanford University | 2026-07-01 | 2026-07-17 | |
| Emotion-Focused Therapy in the Treatment of Prolonged Grief Disorder Emotion-Focused Therapy for Grief, Self-help intervention based on EFT - Prolonged Grief Disorder (PGD) | Not applicable | Recruiting | Universidad Pontificia Comillas | 128 | 2026-04-06 | 2026-09-02 |
| Prolonged Grief Disorder (PGD) Diagnosis in Older Adults: Physicians' Knowledge and Practice PGD Informational Video, Bereavement Educational Video - Physicians' Knowledge and Diagnostic Practices for PGD in Older Adults, Effect of Brief Training on PGD Diagnosis | Not applicable | Not yet recruiting | Ruppin Acdemic Center | 198 | 2026-03-31 | 2026-03-23 |
| Psilocybin for Prolonged Grief Disorder Psilocybin 25 mg, Functional Magnetic Resonance Imaging (fMRI) - Prolonged Grief Disorder | Early Phase 1 | Recruiting | University of Virginia | 12 | 2026-03-24 | 2026-06-23 |
| Understanding and Responding to Grief-Related Needs: A Differentiated Community Approach IGLiteracy, Arm 2 - Individual Self-Help Program (ISelfHP), Arm 3 - Moderated Self-Help Groups (MSHGroups) - Prolonged Grief Disorder (PGD) | Not applicable | Not yet recruiting | ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida | 246 | 2026-03-01 | 2026-02-25 |
| F-PGT - Prolonged Grief Treatment for Families Affected by Suicide F-PGT - Prolonged Grief Disorder (PGD) | Not applicable | Enrolling by invitation | University of Pittsburgh | 30 | 2025-12-17 | 2026-07-15 |
| Transcranial Magnetic Stimulation to Treat Prolonged Grief Disorder Repetitive Transcranial Magnetic Stimulation (rTMS) - Prolonged Grief Disorder, Complicated Grief | Not applicable | Recruiting | Bruyère Health Research Institute. | 15 | 2025-11-28 | 2026-07-10 |
| Technology-supported Interventions for Prolonged Grief Disorder (PGD) Internet-based treatment (GROw) combined with face-to-face videoconferencing sessions with a therapist in BF-GROw group, Internet-based treatment (GROw) supported by the App developed which contains the EMA and EMI tools in iGROw group. - Prolonged Grief Disorder (PGD) | Not applicable | Recruiting | Universitat Jaume I | 141 | 2025-11-10 | 2026-10-20 |
| Adolescent Suicide Loss Survivors Grief Intervention Group Adolescent Grief Group - Grief | Not applicable | Not yet recruiting | Nova Southeastern University | 20 | 2025-09-01 | 2025-09-03 |
| Families Left Behind RIVER, Enhanced care as usual - Grief, Grief Disorder, Prolonged | Not applicable | Recruiting | RAND | 340 | 2025-06-13 | 2025-08-21 |
| A Multifaceted Intervention Strategy for Relatives of End-of-life Patients in the Emergency Department Multi-faceted Intervention - Grief Disorder, Prolonged | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 924 | 2025-06-04 | 2026-07-17 |
| A Swedish Internet CBT for Prolonged Grief Disorder: a Three-armed RCT iCBT for prolonged grief, Active control - Prolonged Grief Disorder | Not applicable | Recruiting | Uppsala University | 270 | 2025-04-23 | 2025-04-29 |
| P-CRP for Recent-Onset Severe Trauma Psychological-cognitive reprocessing procedure (P-CRP)., Expressive Narrative and Symbolic Drawing (ENSD) - Trauma and Stress Related Disorders, Grief (Traumatic Grief and Existential Grief) | Not applicable | Completed | Zahide Betül Baydar | 43 | 2025-03-05 | 2026-07-14 |
| EMDR Grief Protocol for Traumatic Grief After Earthquake-Related Loss EMDR Grief Protocol - Traumatic Grief, Post Traumatic Stress Disorder PTSD | Not applicable | Completed | Istanbul Bilgi University | 78 | 2025-02-23 | 2026-08-20 |
| Feasibility and Efficacy of Individual SH+ Intervention Feasibility and Efficacy of Individual SH+ Intervention - Grief Disorder, Prolonged | Not applicable | Completed | Koç University | 37 | 2024-10-01 | 2025-02-25 |
| Effects of the Integrated Grief Therapy on Psychological Resilience, Post-Traumatic Growth, Traumatic Stress, and Grief Processes in Earthquake Survivors Integrated Grief Therapy (IGT) - Post-traumatic Stress Disorder (PTSD), Grief (Traumatic Grief and Existential Grief) | Not applicable | Active not recruiting | Sakarya University | 190 | 2024-04-12 | 2026-06-11 |
| Empower-Grief: A Study on a Selective Intervention to Prevent Prolonged Grief Disorder EMPOWER, Treatment as usual (TAU) - Grief Disorder, Prolonged | Not applicable | Unknown | ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida | 44 | 2023-08-07 | 2024-02-21 |
| Coping After Loss Through Mindfulness in Adults With Prolonged Grief Disorder Meditation Training, Waitlist - Prolonged Grief Disorder | Not applicable | Recruiting | University Hospital, Caen | 30 | 2023-08-01 | 2025-07-24 |
| Web Based Patient Tutorial on Prolonged Grief Web Based Patient Tutorial on Prolonged Grief Disorder Therapy - Prolonged Grief Disorder | Not applicable | Completed | Columbia University | 34 | 2022-10-01 | 2024-04-04 |
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R41MH118126 (2)