2 unknown, 1 not yet recruiting, 1 recruiting, 1 terminated. 5 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Unknown 2, Not yet recruiting 1, Recruiting 1, Terminated 1 |
| Phase 1 | 1 | Terminated 1 |
| Phase 3 | 1 | Not yet recruiting 1 |
Follow Progressive Multifocal Leukoencephalopathy: new trials by email Literature Review of Progressive Multifocal Leukoencephalopathy trials Research Report on Progressive Multifocal Leukoencephalopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intravenous Brincidofovir as an Antiviral for Treatment of Progressive Multifocal Leukoencephalopathy: A Pilot Study Brincidofovir - Progressive Multifocal Leukoencephalopathy | Phase 2 | Recruiting | National Institute of Neurological Disorders and Stroke (NINDS) | 24 | 2026-06-05 | 2026-07-22 |
| Pembrolizumab in Progressive Multifocal Leukoencephalopathy (PML) in Immunocompromised Patients Without HIV Infection Pembrolizumab, 25 mg/ml solution for intravenous (IV) injection - Progressive Multifocal Leukoencephalopathy | Phase 2 / Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 33 | 2024-04-01 | 2024-02-26 |
| A Phase 2 Study Evaluating JCPyV-specific T Cell Therapy for PML CE-VST01-JC - Progressive Multifocal Leukoencephalopathy | Phase 2 | Unknown | Cellevolve Bio Inc | 60 | 2023-02-01 | 2022-09-16 |
| Treatment of PD-1 Inhibitor in AIDS-associated PML Pembrolizumab - Progressive Multifocal Leukoencephalopathy, AIDS | Phase 2 | Unknown | First Affiliated Hospital of Zhejiang University | 10 | 2019-08-20 | 2019-09-20 |
| Study to Explore the Effect of Mefloquine in Participants With Progressive Multifocal Leukoencephalopathy (PML) mefloquine - Progressive Multifocal Leukoencephalopathy | Phase 1 / Phase 2 | Terminated | Biogen | 37 | 2009-01-01 | 2014-07-31 |
Leukoencephalopathy, Progressive Multifocal (5) · Acquired Immunodeficiency Syndrome (1) · Central Nervous System Diseases (1)
Brain Diseases (5) · Central Nervous System Infections (5) · Central Nervous System Viral Diseases (5) · DNA Virus Infections (5) · Demyelinating Diseases (5) · Encephalitis (5) · Encephalitis, Viral (5) · Infections (5) · Infectious Encephalitis (5) · Leukoencephalopathies (5) · Nervous System Diseases (5) · Neuroinflammatory Diseases (5) · Polyomavirus Infections (5) · Slow Virus Diseases (5) · Virus Diseases (5)
pembrolizumab (2) · Immune Checkpoint Inhibitors (1) · Injections (1) · Mefloquine (1) · Solutions (1) · brincidofovir (1)
Assistance Publique - Hôpitaux de Paris (1) · Biogen (1) · Cellevolve Bio Inc (1) · First Affiliated Hospital of Zhejiang University (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1)
United States (2) · Brazil (1) · China (1) · France (1) · Germany (1) · Italy (1) · Spain (1)
Biao Zhu, PhD (1) · Irene CM Cortese, M.D. (1)
2023 (1)