11 completed. 11 Phase 2, 6 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 11 | Completed 11 |
| Phase 1 | 6 | Completed 6 |
Follow Primary Ovarian Insufficiency: new trials by email Literature Review of Primary Ovarian Insufficiency trials Research Report on Primary Ovarian Insufficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Impact of Granulocyte Colony Stimulating Factor on Premature Ovarian Insufficiency Neupogen - Primary Ovarian Insufficiency, Premature Ovarian Failure | Phase 2 | Completed | Trio Fertility | 11 | 2023-10-13 | 2026-08-20 |
| Intra-ovarian Injection of MSC-EVs in Idiopathic Premature Ovarian Failure Intra-ovarian injection of bone marrow mesenchymal stromal cells-derived extracellular vesicles - Premature Ovarian Failure | Phase 1 / Phase 2 | Completed | Royan Institute | 10 | 2023-02-20 | 2026-07-15 |
| Efficacy of Pentoxifylline and Alpha Lipoic Acid in PCOS Resistant to Clomiphene Citrate Alpha lipoic acid (ALA), Pentoxifylline (PTX), Clomiphene Citrate - Clomiphene Citrate, Resistant Ovary Syndrome | Phase 2 | Completed | Ain Shams University | 120 | 2022-06-05 | 2023-07-20 |
| Immunomodulatory Therapy in Women With Autoimmune Premature Ovarian Insufficiency Rituximab - Autoimmune Diseases, Premature Ovarian Insufficiency | Phase 2 | Completed | Angelica Lindén Hirschberg | 15 | 2019-04-29 | 2024-12-18 |
| Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Female Infertility Human Chorionic Gonadotropin (hCG), Gonadotropins, GNRH-A Triptorelin - Female Infertility, Female Infertility Due to Ovulatory Disorder | Phase 1 / Phase 2 | Completed | Lebanese University | 200 | 2018-02-01 | 2023-05-09 |
| Chinese Medicine(Hu Yang Yang Kun Formula) for Primary Ovarian Insufficiency Chinese medicine granules (HuYang Yang Kun Formula), dehydroepiandrosterone - Primary Ovarian Insufficiency | Phase 1 / Phase 2 | Completed | Guangzhou University of Traditional Chinese Medicine | 48 | 2016-04-01 | 2018-04-10 |
| Transplantation of HUC-MSCs With Injectable Collagen Scaffold for POF HUC-MSCs Transplantation, HUC-MSCs with Injectable Collagen Scaffold Transplantation - Premature Ovarian Failure | Phase 1 / Phase 2 | Completed | Chinese Academy of Sciences | 23 | 2015-10-01 | 2020-01-13 |
| Pregnancy After Stem Cell Transplantation in Premature Ovarian Failure Stem Cell - Premature Ovarian Failure | Phase 1 / Phase 2 | Completed | Al-Azhar University | 10 | 2012-03-01 | 2014-06-02 |
| "It is a Real" The First Baby Of Autologous Stem Cell Therapy in Premature Ovarian Failure Stem cell - Premature Ovarian Failure | Phase 1 / Phase 2 | Completed | Al-Azhar University | 112 | 2012-03-01 | 2015-02-26 |
| GnRH Analogue for Ovarian Function Preservation in Hematopoietic Stem Cell Transplantation Patients Leuprolide Acetate, Questionnaire, Hematopoietic Stem Cell Transplantation - Amenorrhea, Premature Ovarian Failure | Phase 2 | Completed | M.D. Anderson Cancer Center | 60 | 2002-11-01 | 2013-07-09 |
| Hormone Replacement in Young Women With Premature Ovarian Failure TMTDS - Healthy, Osteoporosis | Phase 2 | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 250 | 1999-12-01 | 2007-02-27 |
Polycystic Ovary Syndrome (2) · Amenorrhea (1) · Autoimmune Diseases (1) · Endometriosis (1) · Endometritis (1) · Infertility (1) · Infertility, Female (1) · Leiomyoma (1) · Osteoporosis (1) · Pregnancy, Ectopic (1) · Salpingitis (1) · Uterine Anomalies (1)
Adnexal Diseases (11) · Endocrine System Diseases (11) · Female Urogenital Diseases (11) · Female Urogenital Diseases and Pregnancy Complications (11) · Genital Diseases (11) · Genital Diseases, Female (11) · Gonadal Disorders (11) · Ovarian Diseases (11) · Urogenital Diseases (11) · Cysts (2) · Neoplasms (2) · Ovarian Cysts (2) · Bone Diseases (1) · Bone Diseases, Metabolic (1) · Fallopian Tube Diseases (1)
Chorionic Gonadotropin (1) · Clomiphene (1) · Dehydroepiandrosterone (1) · Filgrastim (1) · Gonadotropins (1) · Hematopoietic Stem Cell Transplantation (1) · LHRH, Ac-Nal(1)-Cpa(2)-Trp(3)-Arg(6)-Ala(10)- (1) · Leuprolide (1) · Menotropins (1) · Pentoxifylline (1) · Rituximab (1) · Stem Cell Transplantation (1) · Surveys and Questionnaires (1) · Thioctic Acid (1) · Triptorelin Pamoate (1)
Al-Azhar University (2) · Ain Shams University (1) · Angelica Lindén Hirschberg (1) · Chinese Academy of Sciences (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Guangzhou University of Traditional Chinese Medicine (1) · Lebanese University (1) · M.D. Anderson Cancer Center (1) · Royan Institute (1) · Trio Fertility (1)
Egypt (3) · China (2) · United States (2) · Canada (1) · Iran (1) · Lebanon (1) · Sweden (1)
Hala N Hosni, Professor (2) · Mahmoud Edessy, Professor (2) · Medhat Kamel, Msc (2) · Faezeh Shekari, Ph.D (1) · Hongyan Yang, professor (1) · Jianwu Dai, Ph.D (1) · Nagwa Al Sabri, Phd (1) · Naoto Ueno, MD, PhD (1) · Nehman Makdissy, Professor (1) · Robert F. Casper, Dr. (1) · Samar El Hamoui, Dr (1) · Sayed Bakri, MD (1) · Syed Bkry, MD (1) · Yehia Wafa, Professor (1)
PMID 11498213, PMID 11821109, PMID 22282904, PMID 24473536, PMID 24905063, PMID 40393653, PMID 41495818, PMID 42334299