18 completed, 12 unknown, 3 recruiting, 3 terminated. 40 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 40 | Completed 18, Unknown 12, Recruiting 3, Terminated 3, Active not recruiting 2, Withdrawn 2 |
Follow Primary Immunodeficiency Diseases: new trials by email Literature Review of Primary Immunodeficiency Diseases trials Research Report on Primary Immunodeficiency Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Exercise Intervention and Immunodeficiency App-based exercise intervention - Primary Antibody Deficiency Disorders | Not applicable | Recruiting | Yale University | 20 | 2026-07-17 | 2026-07-23 |
| A Study to Learn About the C1-Inhibitor Function as Diagnosis for Hereditary Angioedema Technochrom C1-INH Kit - Hereditary Angioedema (HAE) | Not applicable | Recruiting | Takeda | 514 | 2026-05-12 | 2026-05-19 |
| Ex Vivo Evaluation of JAK-inhibitor and Gene Therapeutical Approach in JAK-STAT Related Disorders blood sampling - Primary Immunodeficiency Diseases (PID) | Not applicable | Recruiting | prof. dr. Rik Schrijvers | 20 | 2024-11-21 | 2025-12-03 |
| Virtual Reality on Pain and Fear Levels of Children With Primary Immunodeficiency Virtual reality video watching, Tablet video watching - Primary Immunodeficiency Diseases (PID) | Not applicable | Completed | Dr. Hatice Dönmez | 31 | 2024-09-15 | 2026-06-09 |
| Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside Nicotinamide riboside - Ataxia Telangiectasia | Not applicable | Unknown | The University of Queensland | 10 | 2024-05-01 | 2024-04-18 |
| Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion CliniMACS - Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia in Remission | Not applicable | Active not recruiting | Baylor College of Medicine | 3 | 2023-12-06 | 2026-10-08 |
| Investigation of the Effects of Pulmonary Rehabilitation in Children With Primary Immunodeficiency Inspiratory muscle training, Upper extremity aerobic exercise training, Lower extremity aerobic exercise training - Primary Immunodeficiency | Not applicable | Unknown | Gazi University | 40 | 2023-11-01 | 2023-12-05 |
| Home-based Complex Intervention for Children With Ataxia Telangiectasia Whole-body exercise and respiratory exercise - Ataxia Telangiectasia in Children, Ataxia Telangiectasia | Not applicable | Unknown | University of Plymouth | 40 | 2023-06-01 | 2023-11-29 |
| Evaluating Bronchodilator Response in Patients With Bronchiectasis spirometry, Salbutamol, placebo - Bronchiectasis, Cystic Fibrosis | Not applicable | Unknown | Rambam Health Care Campus | 96 | 2023-05-20 | 2023-07-06 |
| Bronchiectasis Prevalence in Patients With Primary Humoral Immunodefiency in Champagne-Ardenne Region, France Blood test, chest CT scan - Primary Immunodeficiency, Common Variable Immunodeficiency | Not applicable | Completed | CHU de Reims | 46 | 2022-11-28 | 2025-12-18 |
| Feasibility Study to Assess an Adapted Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Transplantation Physical activity program - Haematological Malignancy, Acute Leukemia | Not applicable | Completed | Centre Leon Berard | 15 | 2022-05-25 | 2024-08-21 |
| A Prospective Monocentric Study to Assess the Concordance of Lung MRI Compared to Chest CT Scan to Assess the Extent and Severity of Bronchial and Parenchymal Pulmonary Lesions in Adult Patients With Primary Immune Deficiency (PID) . MRI procedure - Primary Immune Deficiency | Not applicable | Unknown | Hopital Foch | 50 | 2021-11-03 | 2022-07-27 |
| Study of Efficacy and Safety of the Plasmapheresis Method With Albumin Compensation Compared With the Plasmapheresis Method Without Albumin Compensation for Aging Biomarkers Correction in Men and Women Aged 40 to 55 Years Old plasma exchange with albumin, plasma exchange without albumin - Hypercholesterolemia, Hyperbilirubinemia | Not applicable | Unknown | National Medical Research Center for Rehabilitation and Balneology | 80 | 2021-05-12 | 2021-05-21 |
| THC Crossover Study Smoked Cannabis, Vaped Cannabis, Tobacco Cigarette - THC, Cannabis | Not applicable | Completed | University of California, San Francisco | 14 | 2020-10-30 | 2024-07-01 |
| Gene Therapy for X Linked Severe Combined Immunodeficiency Lentiviral Vector Gene Therapy - Gene Therapy | Not applicable | Unknown | Children's Hospital of Chongqing Medical University | 10 | 2020-05-01 | 2020-03-27 |
| Minipooled-IVIG in Primary Immunodeficiency Disease minipooled- Intravenous immunoglobulin(MP-IVIG) - Primary Immunodeficiency | Not applicable | Completed | Assiut University | 15 | 2020-01-01 | 2020-05-12 |
| A Study to Assess a Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Allografts Physical activity program - Haematological Malignancy, Acute Leukemia | Not applicable | Withdrawn | Centre Leon Berard | 2018-12-08 | 2022-02-28 | |
| Severe PID With Lymphoproliferation and Neutropenia FACS analyses, Target Sequencing by NGS ( Next-generation sequencing), Whole Exome Sequencing - Primary Immune-Deficiency (PID) Common Variable Immune Deficiency (CVID) | Not applicable | Completed | University Hospital, Strasbourg, France | 27 | 2018-03-13 | 2026-01-08 |
| The Impact of Exercise on Stress, Fatigue, and Quality of Life in Individuals With Primary Immunodeficiency Disease Exercise Program - Primary Immune Deficiency Disorder, Common Variable Immunodeficiency | Not applicable | Completed | Stockton University | 36 | 2017-06-27 | 2018-09-06 |
| Investigation of Dental Health in Children With Neutrophil Defects: A Clinical Study Oral hygiene advice, non surgical periodontal treatment - Primary Immune Deficiency Disorder, Periodontitis | Not applicable | Completed | Queen Mary University of London | 50 | 2016-12-01 | 2022-11-14 |
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Ataxia Telangiectasia (9) · Common Variable Immunodeficiency (7) · Immunologic Deficiency Syndromes (6) · Severe Combined Immunodeficiency (5) · Anemia, Aplastic (4) · Chediak-Higashi Syndrome (4) · Genetic Diseases, Inborn (4) · Immune System Diseases (4) · Lymphohistiocytosis, Hemophagocytic (4) · Rare Diseases (4) · Wiskott-Aldrich Syndrome (4) · Angioedemas, Hereditary (3) · Ataxia (3) · Communicable Diseases (3)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (40) · Genetic Diseases, Inborn (36) · Immune System Diseases (36) · Immunologic Deficiency Syndromes (34) · Nutritional and Metabolic Diseases (16) · Metabolic Diseases (15) · Pathological Conditions, Signs and Symptoms (15) · DNA Repair-Deficiency Disorders (14) · Hemic and Lymphatic Diseases (13) · Cardiovascular Diseases (11) · Hematologic Diseases (11) · Pathologic Processes (11) · Vascular Diseases (11) · Central Nervous System Diseases (9)
Blood Specimen Collection (4) · Cyclophosphamide (4) · Busulfan (3) · Etoposide (3) · Methotrexate (3) · Antilymphocyte Serum (2) · Cyclosporine (2) · Prednisone (2) · Albumins (1) · Albuterol (1) · Alefacept (1) · Alemtuzumab (1) · Asparaginase (1) · Breathing Exercises (1) · Bronchodilator Agents (1)
Johann Wolfgang Goethe University Hospital (4) · Centre Leon Berard (2) · Fairview University Medical Center (2) · University of South Florida (2) · Assiut University (1) · Baylor College of Medicine (1) · CHU de Reims (1) · Children's Hospital of Chongqing Medical University (1) · Dr. Hatice Dönmez (1) · Emory University (1) · Federal University of São Paulo (1) · Gazi University (1) · Great Ormond Street Hospital for Children NHS Foundation Trust (1) · Hopital Foch (1) · Icahn School of Medicine at Mount Sinai (1)
United States (13) · France (7) · United Kingdom (3) · Germany (2) · Turkey (Türkiye) (2) · Algeria (1) · Australia (1) · Belgium (1) · Brazil (1) · China (1) · Egypt (1) · Israel (1) · Netherlands (1) · Russia (1)
Stefan Zielen, Prof. Dr. (3) · K. Scott Baker (2) · Albertina RB Pizzamiglio, md MSc (1) · Aparecida T Nagao-Dias (1) · Beatriz T Costa Carvalho, md PhD (1) · Caner Aytekin, Assoc. Prof. (1) · Charles K Naspitz, md MSc (1) · Charlotte Cunningham-Rundles (1) · David Coman, MBBS FRACP (1) · Erin Morales, MD (1) · Gideon St. Helen, PhD (1)
PMID 34477998, PMID 25295500, PMID 26095669, PMID 26645295, PMID 28842786, PMID 30251145, PMID 30261899, PMID 30946917, PMID 36285530, PMID 40739200