44 completed, 7 recruiting, 2 terminated, 2 unknown. 42 Not applicable, 5 Phase 4, 2 Early Phase 1, 2 Phase 3, 1 Phase 2.
Follow Pre-exposure Prophylaxis: new trials by email Literature Review of Pre-exposure Prophylaxis trials Research Report on Pre-exposure Prophylaxis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intervention to Reduce Implicit Bias in Pharmacies The adapted PHBI, The NIH Implicit Bias course - Bias, Implicit, HIV | Not applicable | Not yet recruiting | Massachusetts General Hospital | 70 | 2027-07-01 | 2025-11-12 |
| Universal Test and Connect for HIV Service Delivery in South Africa HIV testing, In-depth interview - Human Immunodeficiency Virus, Pre-Exposure Prophylaxis | Recruiting | Johns Hopkins University | 2000 | 2026-01-19 | 2026-01-30 | |
| Gathering Online for Dialogue and Discussion to Enhance Social Support mHealth-Women's CoOp, Virtual Group - Alcohol Misuse, HIV | Not applicable | Recruiting | RTI International | 500 | 2025-04-07 | 2026-05-19 |
| Thailand HIV and Stigma Reduction Study Mobile Healthy Choices (mHC), Finding Respect and Ending Stigma around HIV (FRESH), Standard PrEP Counseling - Pre-Exposure Prophylaxis | Not applicable | Recruiting | University of Massachusetts, Worcester | 154 | 2025-02-20 | 2026-08-31 |
| Centering Those Engaged in Transactional Sex: A PrEP Innovation for Getting To Zero C-PrEP+ - Sex Work, Pre-Exposure Prophylaxis | Early Phase 1 | Active not recruiting | University of Illinois at Chicago | 24 | 2024-12-12 | 2025-09-22 |
| Zambia Healthy Choices Project for Emerging Adults Living With HIV Mobile Healthy Choices (mHC), Motivational Text Messaging (MTM), Standard ART Counseling - Pre-Exposure Prophylaxis | Not applicable | Completed | University of Massachusetts, Worcester | 164 | 2024-04-20 | 2026-08-31 |
| UNCPM 22314 - Pregnancy, Infant and Maternal Health Outcomes Study Initiating daily oral PrEP during pregnancy, Already using daily oral PrEP at the time of pregnancy diagnosis, Initiating injectable PrEP during pregnancy - Pre-exposure Prophylaxis, HIV Prevention | Phase 4 | Recruiting | University of North Carolina, Chapel Hill | 621 | 2024-04-17 | 2026-05-05 |
| Project Phakama: Testing Support Strategies to Empower Young Women on PrEP in South Africa Case management, Food vouchers, PrEP support buddy - Pre-exposure Prophylaxis, HIV Infections | Not applicable | Completed | Johns Hopkins Bloomberg School of Public Health | 304 | 2024-04-16 | 2026-06-18 |
| Improving HIV Prevention Among Heterosexual Men Seeking STI Services in Malawi PrEP eligibility assessment, Rapid HIV antibody testing prior to provision and/or refill of PrEP, PrEP follow-up with a PrEP nurse in accordance with contemporary PrEP guidelines - HIV Infection, Sexually Transmitted Infections | Not applicable | Completed | HIV Prevention Trials Network | 199 | 2024-04-02 | 2025-12-12 |
| Screening Anal HPV Colonization in Men Sex Men Using Pre-exposure Prophylaxis for HIV (ANAPreP'HPV) A prelevement for HPV genotyping and anal cytology will be carried out in addition to the anal swabs taken quarterly to screen for other sexually transmitted infections. - Pre-Exposure Prophylaxis | Not applicable | Unknown | Centre Hospitalier Universitaire de Besancon | 100 | 2024-03-04 | 2024-03-08 |
| Enhancing Communication on Relationship Preservation, Safer Conception and PrEP to Promote HIV Testing in Uganda HOPE Clinical Communication Campaign - HIV, Antenatal Care | Not applicable | Completed | Children's Mercy Hospital Kansas City | 22359 | 2023-09-15 | 2026-10-14 |
| Predictors of Health Service Utilizations Among Key Population in Washington DC Pre-exposure Prophylaxis, HIV | Recruiting | Us Helping Us, People Into Living, Inc. | 100 | 2023-08-25 | 2025-03-10 | |
| Information Seeking About Pre-exposure Prophylaxis Injectable PrEP information, Oral PrEP information - Pre-exposure Prophylaxis | Not applicable | Completed | Penn State University | 314 | 2023-05-30 | 2026-02-09 |
| Development and Evaluation of a PrEP Decision Aid for Women Seeking Domestic Violence Services in Baltimore Individual PrEP Decision Aid, CDC PrEP Video, Shared PrEP Decision Aid - HIV, Violence, Gender-Based | Not applicable | Completed | Johns Hopkins Bloomberg School of Public Health | 53 | 2023-05-10 | 2025-08-22 |
| Pilot Mobile Medical Unit Study for I'm Fully Empowered4Her I'm Fully Empowered for Her (IFE4Her) - HIV Prevention, Pre-exposure Prophylaxis | Not applicable | Completed | University of North Carolina, Chapel Hill | 35 | 2023-04-18 | 2025-08-15 |
| HIV Pre-Exposure Prophylaxis Among an Unrecognized Sexual Minority Population video informational/educational intervention - Pre-Exposure Prophylaxis | Not applicable | Terminated | The Alternative Sexualities Health Research Alliance | 57 | 2023-04-11 | 2025-02-25 |
| Friendship Bench Mental Health Intervention for Adolescent Girls and Young Women in South African PrEP Delivery Settings Youth Friendship Bench SA - Depression, Pre-Exposure Prophylaxis | Not applicable | Completed | University of California, San Francisco | 116 | 2023-04-03 | 2026-06-26 |
| Next Generation Ingestible Sensors for Medication Adherence Measurement Next-generation Reader and ID-Cap System, Truvada for pre-exposure prophylaxis (PrEP), Biktarvy for antiretroviral therapy (ART) - HIV Infection, Adherence, Medication | Phase 3 | Completed | Brigham and Women's Hospital | 15 | 2023-02-06 | 2024-09-25 |
| Le Kip Kip: A Campaign to Change Social Norms and Build Sustainable Demand for PrEP Among Women in South Africa Social Media Campaign, PrEP Champions, Community Mobilization - Pre-exposure Prophylaxis, HIV Infections | Not applicable | Completed | Johns Hopkins Bloomberg School of Public Health | 601 | 2022-10-01 | 2025-07-30 |
| Case Management Dyad Dyadic Case Management - HIV, Pre-exposure Prophylaxis | Not applicable | Recruiting | University of Chicago | 220 | 2022-09-09 | 2026-10-02 |
Showing 20 of 58. Sign in to see all of them.
HIV Infections (9) · Sexually Transmitted Diseases (9) · Acquired Immunodeficiency Syndrome (5) · Medication Adherence (5) · Risk Reduction Behavior (4) · Risk-Taking (2) · Bias, Implicit (1) · Breast Feeding (1) · COVID-19 (1) · Coitus (1) · Contraception Behavior (1) · Coronavirus Infections (1) · Depression (1) · Emergencies (1) · Encephalitis, Japanese (1)
Infections (23) · Communicable Diseases (21) · Genital Diseases (21) · Urogenital Diseases (21) · Behavior (19) · RNA Virus Infections (16) · Virus Diseases (16) · Blood-Borne Infections (14) · Immune System Diseases (14) · Immunologic Deficiency Syndromes (14) · Lentivirus Infections (14) · Retroviridae Infections (14) · Sexually Transmitted Diseases, Viral (14) · Sexually Transmitted Diseases (12) · Disease Attributes (11)
Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (5) · Emtricitabine (2) · Tenofovir (2) · Case Management (1) · Drug Delivery Systems (1) · HIV Testing (1) · Hormonal Contraception (1) · Hydroxychloroquine (1) · Injections (1) · Lamivudine (1) · Motivational Interviewing (1) · Pre-Exposure Prophylaxis (1) · Probenecid (1) · Racivir (1) · SDM (1)
Public Health Foundation Enterprises, Inc. (6) · University of Massachusetts, Worcester (4) · University of Washington (4) · Fenway Community Health (3) · Johns Hopkins Bloomberg School of Public Health (3) · University of North Carolina, Chapel Hill (3) · Emory University (2) · Massachusetts General Hospital (2) · Beth Israel Deaconess Medical Center (1) · Brigham and Women's Hospital (1) · Centre Hospitalier Annecy Genevois (1) · Centre Hospitalier Universitaire de Besancon (1) · Children's Mercy Hospital Kansas City (1) · Columbia University (1) · Duke University (1)
United States (34) · South Africa (5) · Thailand (5) · France (3) · China (2) · Kenya (2) · Malawi (2) · Uganda (2) · Canada (1) · Taiwan (1) · Zambia (1)
Bo Wang, PhD (3) · Susan Buchbinder, MD (3) · Aaron Siegler, PhD (2) · Albert Y Liu, MD, MPH (2) · Douglas Krakower, MD (2) · Katie B Biello, PhD, MPH (2) · Adam W Carrico, PhD (1) · Albert Liu, M.D., MPH (1) · Anjuli Wagner, PhD (1) · Bhakti Hansoti, MD (1) · Bo Wang (1) · Brandon T Gufford, PharmD, PhD (1) · Brianna Norton, DO, MPH (1) · Carol Golin, MD (1) · Carol Strong, PhD (1)
PMID 30681964, PMID 31199326, PMID 33044687, PMID 33258793, PMID 33759792, PMID 34734828, PMID 35537794, PMID 35587370, PMID 37101251, PMID 37131755, PMID 37665622, PMID 37713244, PMID 37713289, PMID 37831485, PMID 37956177, PMID 38045529, PMID 38133600, PMID 38219741, PMID 38412047, PMID 38574278, PMID 39222964, PMID 39312771, PMID 39334032, PMID 39630076, PMID 39806604, PMID 39908084, PMID 39922997, PMID 39992777, PMID 40192662, PMID 40440084, PMID 40531570, PMID 40989241, PMID 41021915, PMID 42098649, PMID 42247072, PMID 42470201
U19HD089881 (4), R01MH109320 (2), R01MH121161 (2), K01MH121124 (1), K23MH098795 (1), K23NR020445 (1), K24AI141036 (1), P01HD112215 (1), P30AI117970 (1), R00MH123369 (1), R01AA030452 (1), R01AI104309 (1), R01AI114310 (1), R01AI125498 (1), R01AI143875 (1)