8 completed, 4 recruiting, 1 unknown. 8 Not applicable, 3 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 5, Recruiting 2, Unknown 1 |
| Phase 4 | 3 | Recruiting 2, Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Pre-Exposure Prophylaxis: new trials by email Literature Review of Pre-Exposure Prophylaxis trials Research Report on Pre-Exposure Prophylaxis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HIV Pre-Exposure Prophylaxis (PrEP) Linkage With Immediate Medications in the Emergency Department Study PrEP Uptake with Rapid Start, Pre-Exposure Prophylaxis (PrEP) Persistence - HIV Pre-exposure Prophylaxis, PrEP | Not applicable | Recruiting | University of Texas Southwestern Medical Center | 250 | 2026-04-08 | 2026-06-02 |
| MAPS PrEP Van Study Pre-Exposure Prophylaxis (PrEP) - HIV Infection | Phase 4 | Completed | Duke University | 7 | 2025-09-17 | 2026-07-24 |
| Improving Access to PrEP (HIV Prevention Medication) for People in Underserved Areas of Rio de Janeiro Oral Pre-Exposure Prophylaxis (PrEP) (Tenofovir Disoproxil Fumarate/Emtricitabine), Community-Based PrEP Delivery Model, Telehealth and mHealth Support - HIV Infections | Not applicable | Recruiting | Oswaldo Cruz Foundation | 400 | 2025-09-01 | 2026-05-13 |
| PrEP4Her: Developing a Novel Strategy to Implement PrEP Into Women's Healthcare PrEP acronym (pre-exposure prophylaxis) - PrEP Precriptions for Reproductive Aged Women | Completed | University of Alabama at Birmingham | 1377 | 2023-09-22 | 2026-01-26 | |
| Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP community-friendly health recovery program, Pre-Exposure Prophylaxis and Post-Exposure Prophylaxis - Hiv, Opioid Use Disorder | Phase 4 | Recruiting | University of Connecticut | 256 | 2023-03-01 | 2026-06-15 |
| Next Generation Ingestible Sensors for Medication Adherence Measurement Next-generation Reader and ID-Cap System, Truvada for pre-exposure prophylaxis (PrEP), Biktarvy for antiretroviral therapy (ART) - HIV Infection, Adherence, Medication | Phase 3 | Completed | Brigham and Women's Hospital | 15 | 2023-02-06 | 2024-09-25 |
| Providing PrEP, Hepatitis C Treatment, and MOUD Through Telemedicine at Greensboro SSP Suboxone, Truvada, Mavyret - Opioid Use, Opioid Use Disorder | Not applicable | Completed | Duke University | 17 | 2022-02-17 | 2023-04-27 |
| ANCHORS Alcohol & Sexual Health Study: UH3 Project PrEP acronym (pre-exposure prophylaxis), Initial Web Survey, Interactive Voice Response (IVR) monitoring - Alcohol Use, Unspecified, Substance Use | Phase 4 | Recruiting | University of Florida | 88 | 2021-01-12 | 2025-07-10 |
| Providing Suboxone and PrEP Using Telemedicine Suboxone, PrEP - Opioid Use, Opioid-use Disorder | Not applicable | Completed | Duke University | 17 | 2020-11-09 | 2023-06-09 |
| CRUSH-PrEP for Women Project Pre Exposure Prophylaxis, Characteristics of women who enroll, referral sources of women who enroll - Sexually Transmitted Diseases, HIV | Not applicable | Completed | University of California, San Francisco | 30 | 2016-05-01 | 2019-09-11 |
| Introducing PrEP Into HIV Combination Prevention - Kenya Truvada - HIV | Not applicable | Unknown | LVCT Health | 2100 | 2015-08-01 | 2016-04-28 |
| Comprehensive HIV Prevention Package for MSM in Southern Africa: Pilot Study (Sibanye Health Project) Condom choices, Condom-compatible lubricant choices, Couples HIV counseling and testing (CVCT) - HIV | Not applicable | Completed | Emory University | 100 | 2015-02-01 | 2018-09-17 |
| Gender-Specific Combination HIV Prevention for Youth in High Burden Settings (MP3-Youth) Male-Specific Intervention Package, Female-Specific Intervention Package, Pre-Exposure Prophylaxis (Females) - HIV, Adolescent Behavior | Not applicable | Completed | New York University | 1215 | 2014-11-01 | 2022-02-18 |
Acquired Immunodeficiency Syndrome (3) · HIV Infections (3) · Opioid-Related Disorders (3) · Risk Reduction Behavior (2) · Adolescent Behavior (1) · Alcohol Drinking (1) · Cognitive Dysfunction (1) · Coitus (1) · Emergencies (1) · Hepatitis C (1) · Homosexuality (1) · Medication Adherence (1) · Sexual Behavior (1) · Sexually Transmitted Diseases (1) · Substance-Related Disorders (1)
Duke University (3) · Brigham and Women's Hospital (1) · Emory University (1) · LVCT Health (1) · New York University (1) · Oswaldo Cruz Foundation (1) · University of Alabama at Birmingham (1) · University of California, San Francisco (1) · University of Connecticut (1) · University of Florida (1) · University of Texas Southwestern Medical Center (1)
United States (11) · Kenya (2) · Brazil (1) · South Africa (1)
Mehri McKellar, MD (3) · A.D. McNaghten, PhD, MHSA (1) · Ann Kurth, PhD, CNM (1) · Chris Beyrer, MD, MPH (1) · Helgar K Musyoki, MPH (1) · Irene Inwani, MD, MPH (1) · Jacqueline Hodges, MD, MPH (1) · Janet Myers, PhD (1) · Jasmine Buttolph, MPH (1) · Kimberly A Koester, MA (1) · Lawrence J Gelmon, MD.MPH (1) · Linda-Gail Bekker, MBChB, PhD (1) · Mi-Suk Kang Dufour, PhD (1) · Michael Copenhaver, PhD (1) · Michael Mugavero, MD (1)
PMID 25325296, PMID 25513954, PMID 28274904, PMID 36463214, PMID 37399447, PMID 38532395
P30AI064518 (2), F31AA028751 (1), R01AI094607 (1), R34MH128002 (1), UH3AA026214 (1)