7 completed, 2 unknown, 2 withdrawn, 1 not yet recruiting. 3 Not applicable, 3 Phase 3, 3 Phase 4, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 2, Recruiting 1 |
| Phase 3 | 3 | Not yet recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 4 | 3 | Completed 2, Terminated 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Post-thrombotic Syndrome: new trials by email Literature Review of Post-thrombotic Syndrome trials Research Report on Post-thrombotic Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Design and Rationale of the COLT Study Colchicine 0.5 MG Oral Tablet, Placebo - Venous Thrombosis Deep (Limbs), Post-thrombotic Syndrome | Phase 3 | Not yet recruiting | Azienda Sanitaria Locale ASL 6, Livorno | 940 | 2026-06-01 | 2026-02-25 |
| DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis ClotTriever System, Commercially available/market approved anticoagulation medication including but not limited to: Heparin Sodium, Coumadin, Rivaroxaban, Apixaban, etc. - Venous Thromboembolism, Deep Venous Thrombosis | Not applicable | Recruiting | Inari Medical | 300 | 2023-01-06 | 2026-11-03 |
| The MUFFIN-PTS Trial Micronized Purified Flavonoid Fraction, Placebo - Post-Thrombotic Syndrome | Phase 3 | Unknown | Sir Mortimer B. Davis - Jewish General Hospital | 88 | 2022-02-04 | 2023-11-30 |
| Mechanisms of Deep Vein Thrombosis (DVT) and Vein Wall Fibrosis Rosuvastatin - Post-thrombotic Syndrome, Deep Vein Thrombosis Leg | Phase 1 / Phase 2 | Unknown | Khanh Nguyen | 30 | 2021-06-01 | 2021-10-15 |
| Pediatric High-Risk Deep Venous Thrombosis Lytic Outcomes Trial Recombinant tissue plasminogen activator (rt-PA), Standard Anticoagulation Therapy - Deep Vein Thrombosis, Post-Thrombotic Syndrome | Phase 3 | Withdrawn | University of Colorado, Denver | 2018-07-01 | 2018-08-10 | |
| Novel PET/CT and Treatment Strategies to Reduce PTS Following DVT PET/CT - Deep Venous Thrombosis, Post-thrombotic Syndrome | Not applicable | Completed | Massachusetts General Hospital | 50 | 2017-12-20 | 2026-08-18 |
| Treatment of the Postthrombotic Syndrome With the Oblique Stent - TOPOS Study sinus-Obliquus Stent System - Post-thrombotic Syndrome, Iliac Vein Compression Syndrome | Completed | Optimed Medizinische Instrumente GmbH | 60 | 2016-12-01 | 2021-01-12 | |
| Prospective Evaluation of the QoL of Patients With PTS Who Receive Compression Therapy and Sulodexide Sulodexide, Compression therapy - Post-thrombotic Syndrome | Phase 4 | Terminated | Bama GeVe, S.L.U. | 13 | 2015-09-01 | 2017-08-31 |
| Bern Venous Stent Registry CE-certified dedicated venous stents - Post-thrombotic Syndrome | Completed | University of Zurich | 548 | 2015-01-01 | 2023-10-12 | |
| Treatment of Chronic Deep Vein Thrombosis (DVT) and Post-Thrombotic Syndrome (PTS) With the EkoSonic® Endovascular System EkoSonic® Endovascular System, Alteplase - Deep Vein Thrombosis, Post-thrombotic Syndrome | Phase 4 | Completed | Boston Scientific Corporation | 81 | 2014-07-10 | 2021-07-19 |
| Treadmill Pilot Study (Invasive Pressure Measurements in PTS) PTA & stenting - Post-thrombotic Syndrome, May-Thurner Syndrome | Completed | Maastricht University Medical Center | 24 | 2013-12-01 | 2015-10-21 | |
| Elastic Compression Stockings for Prevention of Post-thrombotic Syndrome 25mmHg ECS, 35 mmHg ECS - Deep Vein Thrombosis, Post-thrombotic Syndrome | Not applicable | Completed | Laboratoires Innothera | 350 | 2012-06-29 | 2020-01-22 |
| Practicability of Gliding Aids for Medical Compression Stockings Gliding aids for medical compression stockings - Chronic Venous Insufficiency, Post-thrombotic Syndrome | Phase 4 | Completed | University of Zurich | 40 | 2010-11-01 | 2013-06-24 |
| The 36-month Extension to Follow up Sub Study Postphlebitic Syndrome, Post-Thrombotic Syndrome | Withdrawn | Sir Mortimer B. Davis - Jewish General Hospital | 2004-06-01 | 2018-04-18 |
Postthrombotic Syndrome (14) · Venous Thrombosis (10) · May-Thurner Syndrome (3) · Venous Thromboembolism (2) · Inflammation (1) · Patient Compliance (1) · Postphlebitic Syndrome (1) · Thrombosis (1) · Treatment Adherence and Compliance (1) · Venous Insufficiency (1)
Cardiovascular Diseases (14) · Embolism and Thrombosis (14) · Vascular Diseases (14) · Thrombosis (13) · Venous Insufficiency (13) · Peripheral Vascular Diseases (4) · Venous Thrombosis (4) · Cardiovascular Abnormalities (3) · Congenital Abnormalities (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Vascular Malformations (3) · Behavior (2) · Health Behavior (2) · Thromboembolism (2) · Pathologic Processes (1)
Tissue Plasminogen Activator (2) · Colchicine (1) · Positron Emission Tomography Computed Tomography (1) · Rivaroxaban (1) · Rosuvastatin Calcium (1) · Stents (1) · Tablets (1) · Warfarin (1) · apixaban (1) · glucuronyl glucosamine glycan sulfate (1)
Sir Mortimer B. Davis - Jewish General Hospital (2) · University of Zurich (2) · Azienda Sanitaria Locale ASL 6, Livorno (1) · Bama GeVe, S.L.U. (1) · Boston Scientific Corporation (1) · Inari Medical (1) · Khanh Nguyen (1) · Laboratoires Innothera (1) · Maastricht University Medical Center (1) · Massachusetts General Hospital (1) · Optimed Medizinische Instrumente GmbH (1) · University of Colorado, Denver (1)
Switzerland (4) · United States (4) · Austria (2) · Canada (2) · Germany (2) · Netherlands (2) · Finland (1) · France (1) · Spain (1) · United Kingdom (1)
Nils Kucher, Prof. Dr. med. (2) · Cees Wittens, MD, PhD (1) · Jean-Philippe Galanaud, MD, PhD (1) · Josep Marinel.lo (1) · Khanh P Nguyen, MD (1) · Marilyn J Manco-Johnson, MD (1) · Mark Garcia, MD (1) · Stephen Black, MD (1) · Steven Abramowitz, MD (1) · Susan R Kahn, MD, MSc (1) · Susan R. Kahn, M.D., M.Sc. (1) · Xhorlina Marko, MD (1)
PMID 25579875, PMID 27061685, PMID 29550177, PMID 30391776, PMID 30667348, PMID 31659739, PMID 31983322, PMID 33272030, PMID 33840477, PMID 34518263, PMID 36455606, PMID 39491572, PMID 39968829
R01HL137913 (1)