7 completed, 3 terminated, 1 not yet recruiting, 1 recruiting. 4 Phase 3, 2 Not applicable, 2 Phase 2, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Completed 3, Recruiting 1 |
| Not applicable | 2 | Completed 1, Terminated 1 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
| Phase 4 | 2 | Terminated 1, Withdrawn 1 |
Follow Pediatric Crohn's disease: new trials by email Literature Review of Pediatric Crohn's disease trials Research Report on Pediatric Crohn's disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Modulen IBD for Induction and Maintenance of Remission in Pediatric Crohn's Disease Crohn Disease, Inflammatory Bowel Diseases | Not yet recruiting | Assiut University | 40 | 2026-09-10 | 2026-09-16 | |
| Real World Evidence Study With Restrictive Diet and Otral Nutritional Supplementation on Pediatric Patients With Active Chron Disease Crohn Disease | Completed | Outcomes'10 | 58 | 2024-02-01 | 2025-10-08 | |
| A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON) Mirikizumab - Ulcerative Colitis, Ulcerative Colitis Chronic | Phase 3 | Recruiting | Eli Lilly and Company | 150 | 2021-05-26 | 2026-10-07 |
| Trial of Enhanced Pre-Consent Discussion Enhanced Pre-Consent Discussion, Standard Pre-consent Discussion - Pediatric Crohn's Disease | Not applicable | Completed | Children's Hospital Medical Center, Cincinnati | 241 | 2016-10-01 | 2020-01-18 |
| Low Dose Oral Methotrexate in Pediatric Crohn's Disease Patients Initiating Anti-Tumor Necrosis Factor (Anti-TNF) Therapy Methotrexate, Sugar pill (placebo) - Pediatric Crohn's Disease | Phase 3 | Completed | University of North Carolina, Chapel Hill | 306 | 2016-10-01 | 2023-04-12 |
| An Efficacy and Safety Study of Infliximab Dose Escalation in Pediatric Participants With Inflammatory Bowel Disease Infliximab - Inflammatory Bowel Diseases | Phase 4 | Terminated | Janssen Scientific Affairs, LLC | 53 | 2016-04-01 | 2025-02-04 |
| Mission is Remission®: How Can a Disease Self-management Website Change Care? Mission is Remission® - Pediatric Crohn's Disease, Pediatric Ulcerative Colitis | Not applicable | Terminated | IWK Health Centre | 39 | 2016-04-01 | 2019-03-01 |
| Post-Marketing Surveillance of Humira in Korean Pediatric Crohn's Disease (CD) Patients Under the "New-Drug Re-examination" Pediatric Crohn's Disease | Completed | AbbVie | 143 | 2015-09-24 | 2018-12-19 | |
| Efficacy and Safety of Top-down Therapy in Pediatric Crohn's Disease Top-down, Step-up - Pediatric Crohn's Disease | Phase 4 | Withdrawn | University of Roma La Sapienza | 2012-12-01 | 2013-03-06 | |
| Clinical Study of TA-650 in Pediatric Patients With Crohn's Disease TA-650 - Pediatric Crohn's Disease | Phase 3 | Completed | Tanabe Pharma Corporation | 14 | 2012-03-01 | 2026-01-07 |
| High Dose Oral 4-Aminosalicylic Acid (PASER®) to Control Acute Flares of Mild to Moderate Crohn's Disease in Children 4-Aminosalicylic acid extended release granules - Crohn's Disease | Phase 2 | Terminated | Jacobus Pharmaceutical | 2 | 2007-06-01 | 2017-09-21 |
| Trial of Growth Hormone Therapy in Pediatric Crohn's Disease growth hormone, cortecosteroid - Crohn's Disease | Phase 2 | Completed | Children's Hospital Medical Center, Cincinnati | 22 | 2005-04-01 | 2020-10-30 |
| A Study of the Safety and Efficacy of Infliximab (Remicade) in Pediatric Patients With Crohn's Disease infliximab - Crohn Disease | Phase 3 | Completed | Centocor, Inc. | 112 | 2003-02-01 | 2011-05-17 |
Crohn Disease (7) · Inflammatory Bowel Diseases (4) · Pediatric ulcerative colitis (3) · Colitis, Ulcerative (2)
Digestive System Diseases (8) · Gastroenteritis (8) · Gastrointestinal Diseases (8) · Intestinal Diseases (8) · Inflammatory Bowel Diseases (4) · Colitis (2) · Colonic Diseases (2)
Infliximab (4) · Aminosalicylic Acid (1) · Azathioprine (1) · Budesonide (1) · Growth Hormone (1) · Methotrexate (1) · Methylprednisolone (1) · Prednisone (1) · Sugars (1) · mirikizumab (1)
Children's Hospital Medical Center, Cincinnati (2) · AbbVie (1) · Assiut University (1) · Centocor, Inc. (1) · Eli Lilly and Company (1) · IWK Health Centre (1) · Jacobus Pharmaceutical (1) · Janssen Scientific Affairs, LLC (1) · Outcomes'10 (1) · Tanabe Pharma Corporation (1) · University of North Carolina, Chapel Hill (1) · University of Roma La Sapienza (1)
United States (6) · Canada (2) · Italy (2) · Japan (2) · Spain (2) · Austria (1) · Belgium (1) · Brazil (1) · Germany (1) · Israel (1) · Netherlands (1) · Norway (1) · Poland (1) · Portugal (1) · South Korea (1)
Anthony R Otley, MD MSc (1) · David P Jacobus, MD (1) · Ellen Lipstein, MD, MPH (1) · Eunjung Gu, MS (1) · George D Ferry, MD (1) · Joel R Rosh, MD (1) · Kathy L Ales, MD (1) · Kazuoki Kondo, MD (1) · Lee Denson, M.D. (1) · Marina Aloi, Investigator (1) · Marla C Dubinsky, MD (1) · Melvin B. Heyman, M.D., M.P.H. (1)
PMID 17324398, PMID 19081527, PMID 30114224, PMID 37004887, PMID 40243391
2015 (1), U19AR069525 (1)