10 completed, 1 unknown, 1 withdrawn. 12 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 12 | Completed 10, Unknown 1, Withdrawn 1 |
| Phase 3 | 1 | Completed 1 |
Follow Pathological Gambling: new trials by email Literature Review of Pathological Gambling trials Research Report on Pathological Gambling
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Intranasal Naloxone on Gambling Urges and Craving in Gambling Disorder Naloxone hydrochloride, Placebo - Pathological Gambling, Gambling Disorder | Phase 2 | Unknown | Finnish Institute for Health and Welfare | 126 | 2018-02-22 | 2019-07-16 |
| Milk Thistle in Pathological Gambling Placebo, Milk Thistle - Pathological Gambling, Gambling Disorder | Phase 2 | Completed | University of Chicago | 55 | 2015-01-01 | 2026-07-07 |
| Community Reinforcement Approach and Family Training (CRAFT) for Problem Gambling CRAFT treatment, Treatment as Usual - Pathological Gambling | Phase 2 | Withdrawn | Colchester East Hants Health Authority | 2011-06-03 | 2020-01-23 | |
| Clinical Study to Determine if Ecopipam Can Reduce Urges to Gamble Ecopipam - Pathological Gambling | Phase 2 | Completed | Emalex Biosciences Inc. | 34 | 2010-10-01 | 2024-05-14 |
| D1 and D2 Dopamine Receptors in Gambling and Amphetamine Reinforcement Haloperidol, Fluphenazine, Dexedrine - Pathological Gambling | Phase 2 | Completed | Centre for Addiction and Mental Health | 60 | 2009-09-01 | 2016-04-25 |
| Tolcapone Treatment of Pathological Gambling Tolcapone - Pathological Gambling | Phase 2 | Completed | University of Chicago | 24 | 2009-06-01 | 2023-02-23 |
| Topiramate Trial for Pathological Gamblers Topiramate flexible dosage, Placebo matching tablets, 4-session gambling cognitive restructuring - Pathological Gambling | Phase 2 | Completed | University of Sao Paulo | 38 | 2009-06-01 | 2013-05-03 |
| Investigation of Naltrexone for Pathological Gambling Naltrexone, Placebo - Pathological Gambling | Phase 2 | Completed | Yale University | 9 | 2009-02-01 | 2017-10-13 |
| Memantine Treatment Study of Pathological Gambling Memantine Hydrochloride - Pathological Gambling | Phase 2 | Completed | Yale University | 29 | 2007-12-01 | 2013-04-08 |
| Cognitive Behavioral Therapy for Pathological Gambling Cognitive Behavioral Therapy, Wait-list - Pathological Gambling | Phase 2 | Completed | University of Minnesota | 76 | 2006-06-01 | 2010-01-05 |
| Nalmefene Gambling Study: Study of Nalmefene HCl in the Treatment of Pathological Gambling nalmefene HCl, Placebo - Pathological Gambling | Phase 2 / Phase 3 | Completed | Somaxon Pharmaceuticals | 233 | 2005-08-01 | 2008-05-19 |
| Indicated Prevention With At-Risk Gamblers Personalized Feedback Intervention, Cognitive Behavioral Intervention - Gambling, Pathological Gambling | Phase 2 | Completed | University of Washington | 225 | 2003-07-01 | 2013-12-11 |
Gambling (12) · Behavior, Addictive (1)
Behavior (12) · Disruptive, Impulse Control, and Conduct Disorders (12) · Mental Disorders (12) · Risk-Taking (12) · Compulsive Behavior (1) · Impulsive Behavior (1)
Cognitive Behavioral Therapy (2) · Dextroamphetamine (1) · Fluphenazine (1) · Haloperidol (1) · Lactose (1) · Memantine (1) · Naloxone (1) · Naltrexone (1) · Silymarin (1) · Sugars (1) · Therapeutics (1) · Tolcapone (1) · Waiting Lists (1) · ecopipam (1) · milk-thistle extract (1)
University of Chicago (2) · Yale University (2) · Centre for Addiction and Mental Health (1) · Colchester East Hants Health Authority (1) · Emalex Biosciences Inc. (1) · Finnish Institute for Health and Welfare (1) · Somaxon Pharmaceuticals (1) · University of Minnesota (1) · University of Sao Paulo (1) · University of Washington (1)
United States (7) · Canada (2) · Brazil (1) · Finland (1)
Jon E Grant, MD, JD (2) · Daniela Lobo, MD, Ph.D. (1) · David Hodgins, PhD (1) · Donald Black, MD (1) · Greg Purvis, MSc (1) · Hannu Alho, Prof. (1) · Jon E Grant, JD, MD, MPH (1) · Jon E Grant, MD, JD, MPH (1) · Jon Grant, MD (1) · Marc N Potenza, M.D., Ph.D. (1) · Marc N. Potenza, M.D, Ph.D. (1) · Marc Potenza, MD (1) · Mary E Larimer, Ph.D (1) · Philip Jochelson, MD (1) · Timothy Fong, MD (1)
PMID 36130734, PMID 20721537, PMID 22188239, PMID 23953269, PMID 25166480, PMID 36919514, PMID 38478366
2017 (1), K23MH069754 (1), R21MH067026 (1)