9 completed, 8 recruiting, 4 not yet recruiting, 3 enrolling by invitation. 22 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 22 | Completed 7, Recruiting 6, Not yet recruiting 4, Active not recruiting 2, Enrolling by invitation 2, Unknown 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Overweight (BMI > 25): new trials by email Literature Review of Overweight (BMI > 25) trials Research Report on Overweight (BMI > 25)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fasting, Exercise, and Diet to Activate Autophagy in Depression Performance test - Depression - Major Depressive Disorder, Overweight (BMI > 25) | Not applicable | Not yet recruiting | University of Zurich | 120 | 2026-09-11 | 2026-06-24 |
| SSRD and Overweight Dietary intervention with SSRD in combination with feedback information about the metabolic profile, Dietary intervention with SSRD without any feedback on metabolic profile - Overweight (BMI > 25) | Not applicable | Not yet recruiting | Region Skane | 300 | 2026-09-01 | 2026-04-29 |
| Assessment of Metabolic Changes in Response to Glcuose Intake in Women With Polyendocrine Metabolic Ovarian Syndrome (PMOS) Oral Clucose Tolerance Test (oGTT) - PCOS (Polycystic Ovary Syndrome), Insulinemic Response | Not applicable | Not yet recruiting | University of Zurich | 40 | 2026-08-01 | 2026-07-07 |
| Assess the Effects of Replacing Foods High in Refined Carbohydrates With Avocado on Biomarkers of Inflammation. Avocado, Control - Overweight (BMI > 25), Obesity (BMI>30) | Not applicable | Recruiting | Midwest Center for Metabolic and Cardiovascular Research | 38 | 2026-07-02 | 2026-08-27 |
| AIM-WEIGHT: AI-Guided Microbiome-Targeted Nutritional Intervention for Weight Loss AI-Guided Microbiome-Targeted Nutritional Supplement, Matching Placebo (B), Lifestyle counselling - Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities, Overweight (BMI > 25) | Not applicable | Enrolling by invitation | Varol TUNALI | 80 | 2026-07-01 | 2026-09-29 |
| IMPACT: Immune and Musculoskeletal Physiological Adaptations to Combined Exercise Training & Nutrition Milk, Greek Yogurt, Exercise training - Overweight (BMI > 25), Males and Females | Not applicable | Not yet recruiting | York University | 60 | 2026-05-01 | 2026-04-07 |
| To Test the Effectiveness and Implementation Approach of a 3-month PILI Pasifika Program Lifestyle Program With Components of Social Determinants of Health Activities in Real-world Settings (Clinical and Non-clinical Settings) Across 3 Years PILI (Partnership for Improving Lifestyle Intervention) Pasifika Program - Cardiometabolic Conditions, Hypertension (HTN) | Not applicable | Enrolling by invitation | University of Hawaii | 400 | 2026-05-01 | 2026-06-09 |
| Effect of Probiotics on Appetite Regulation in Adults With Overweight/Obesity Probiotic supplementation, Placebo - Healthy, Overweight (BMI > 25) | Not applicable | Recruiting | Maastricht University Medical Center | 98 | 2026-03-18 | 2026-08-12 |
| Sustainable and Inclusive Use of Alternative Proteins in Mediterranean Supply Chains (CIPROMED) Mediterranean Diet with Control Products (chronic phase), Mediterranean Diet with Insect Protein Bread (chronic phase), Mediterranean Diet with Seaweed-Based Burger (chronic phase) - Food Preferences, Satiety and Food Intake | Not applicable | Recruiting | University of Bologna | 40 | 2026-03-18 | 2026-05-04 |
| Limosilactobacillus Fermentum CRL 1446 - CONICET CASASCO Limosilactobacillus fermentum 1446 CRL CONICET 2.20E+9 CFU, Placebo (inert excipient) - Disbiosis, Obesity | Not applicable | Active not recruiting | PINER Pastor Manfredi Winery | 80 | 2026-02-02 | 2026-05-14 |
| Time Restricted-EAting for Type 2 Diabetes and MEtabolic Health: the TEA TIME Trial Time-restricted eating, Standard lifestyle - Type 2 Diabetes, Overweight (BMI > 25) | Not applicable | Recruiting | Mount Sinai Hospital, Canada | 112 | 2026-02-01 | 2026-02-11 |
| Gummy Candies With Maqui Berry GM, Control, GMM - Overweight (BMI > 25), Obesity & Overweight | Not applicable | Completed | Gonzalo Jorquera, PhD | 10 | 2025-12-02 | 2026-01-28 |
| Effects of Yerba Mate Supplementation on Metabolic Health, Physical Function, and Cognition in Older Adults With Excess Adiposity Yerba Mate, Placebo - Overweight (BMI > 25), Obesity & Overweight | Not applicable | Completed | University of North Alabama | 25 | 2025-11-15 | 2026-10-20 |
| Effect of Low Volume Sprint Interval Training on Cardiorespiratory Fitness High intensity interval training - Inactivity, Physical, Overweight (BMI > 25) | Not applicable | Recruiting | California State University, San Marcos | 60 | 2025-11-05 | 2026-08-24 |
| Global Overweight and oBesE (GLOBE) Patient Registry, Development and Implementation of Disease-specific: Severity, Quality of Life and Cost Instruments. Overweight (BMI > 25), Obesity & Overweight | Recruiting | Medialis Ltd. | 500 | 2025-11-01 | 2025-11-14 | |
| Anti-Inflammatory Effects of Pecan Nut Oil Supplementation in Adults With Overweight: A Randomized Controlled Parallel-Group Clinical Trial Pecan nut oil supplementation - Overweight (BMI > 25) | Not applicable | Recruiting | Universidad Autonoma de Nuevo Leon | 50 | 2025-10-15 | 2026-03-27 |
| Effect of Ketone Esters on Liver Fat Content and Metabolic Function bis-octanoyl (R)-1,3-butanediol (C8 ketone di-ester), Placebo - MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Obesity | Phase 2 | Recruiting | Washington University School of Medicine | 40 | 2025-09-26 | 2026-07-15 |
| Intervention Based on the Dietary Guidelines for the Brazilian Population for the Treatment of Overweight and Obesity Collective Intervention Based on the Dietary Guidelines for the Brazilian Population, Control Group: Individualized Care - Obesity & Overweight, Overweight (BMI > 25) | Not applicable | Active not recruiting | Federal University of Health Science of Porto Alegre | 60 | 2025-05-01 | 2026-04-20 |
| Combined Training (Strength and Endurance) and the Serum Levels of Myostatin and Hormone-sensitive Lipase in Overweight and Obese Men Upper Body Combined Training, Lower Body Combined Training - Overweight (BMI > 25), Obesity (BMI>30) | Not applicable | Completed | Arya Habibi | 36 | 2024-05-01 | 2026-06-23 |
| CHANGES IN SLEEP QUALITY AND BODY COMPOSITION FOLLOWING A MULTIMODAL LIFESTYLE INTERVENTION IN OLDER WOMEN Multimodal Lifestyle Intervention - Obesity, Overweight (BMI > 25) | Not applicable | Completed | Saglik Bilimleri Universitesi | 36 | 2024-01-15 | 2026-08-03 |
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Overweight (27) · Obesity (12) · Diabetes Mellitus, Type 2 (5) · Hypertension (3) · Weight Loss (3) · Inflammation (2) · Sleep Initiation and Maintenance Disorders (2) · Depression (1) · Diabetes Mellitus (1) · Diabetes, Gestational (1) · Dysbiosis (1) · Dyslipidemias (1) · Food Preferences (1) · Glucose Intolerance (1) · Hypercholesterolemia (1)
Body Weight (27) · Nutrition Disorders (27) · Nutritional and Metabolic Diseases (27) · Overnutrition (27) · Pathological Conditions, Signs and Symptoms (27) · Signs and Symptoms (27) · Endocrine System Diseases (8) · Glucose Metabolism Disorders (7) · Metabolic Diseases (7) · Diabetes Mellitus (6) · Behavior (5) · Pathologic Processes (4) · Body Weight Changes (3) · Cardiovascular Diseases (3) · Lipid Metabolism Disorders (3)
Diet Therapy (1) · Diet, Mediterranean (1) · Dietary Supplements (1) · Exercise (1) · Glucose Tolerance Test (1) · High-Intensity Interval Training (1) · Milk (1)
Maastricht University Medical Center (2) · University of Zurich (2) · Arya Habibi (1) · Bioagile Therapeutics Pvt. Ltd. (1) · California State University, San Marcos (1) · Chang Gung Memorial Hospital (1) · Federal University of Health Science of Porto Alegre (1) · Gonzalo Jorquera, PhD (1) · Hofseth Biocare ASA (1) · Medialis Ltd. (1) · Midwest Center for Metabolic and Cardiovascular Research (1) · Mount Sinai Hospital, Canada (1) · PINER Pastor Manfredi Winery (1) · Region Skane (1) · Saglik Bilimleri Universitesi (1)
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Ali Abdul-Sater, PhD (1) · Andrea Josse, PhD (1) · Divya Divya (1) · Freddy Halvadar, PhD (1) · Jonathan Little (1) · Joseph K Kaholokula, PhD (1) · Maria Letizia Petroni, Professor (1) · Nia Aitaoto, PhD (1) · Nicholas Cheng, MSc (1) · Poulami Dasgupta (1) · Raul Francisco Pastor, MD (1) · Samuel Klein, MD (1) · Sheri-Ann Daniels, EdD (1)
2025 (1), OT2HL158287 (1)