16 completed, 12 recruiting, 4 not yet recruiting, 3 unknown. 14 Not applicable, 11 Phase 2, 3 Phase 1, 3 Phase 3, 1 Early Phase 1.
Follow Oral Cavity Cancer: new trials by email Literature Review of Oral Cavity Cancer trials Research Report on Oral Cavity Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Risk Factors of Jaw Osteoradionecrosis in Oral Cavity Cancer Patients Post-Radiotherapy Osteoradionecrosis, Radiotherapy | Not yet recruiting | AO Innovation Translation Center | 1000 | 2027-03-01 | 2026-09-23 | |
| Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral Lesions 5-Amino Levulinic Acid - Oral Cancer, Oral Cavity Cancer | Phase 2 | Not yet recruiting | University of Massachusetts, Boston | 65 | 2026-09-01 | 2026-03-19 |
| Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer [64Cu]CM500, [68Ga]CM500, PET/MR - Bladder Cancer, Glioma | Early Phase 1 | Not yet recruiting | Lumina Pharmaceuticals Inc | 40 | 2026-09-01 | 2026-08-28 |
| Study to Identify Biomarkers of Oral Cavity Cancer Response to Neoadjuvant Immunotherapy Prior to Definitive Surgery Pembrolizumab, Patient-Specific Culture Vessel - Oral Cavity Cancer | Not applicable | Recruiting | University of Wisconsin, Madison | 20 | 2026-04-15 | 2026-09-16 |
| Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN) Toripalimab + Chemotherapy, Toripalimab, Chemoradiotherapy or radiation - Head and Neck Cancer, Squamous Cell Carcinoma | Phase 2 | Recruiting | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 75 | 2026-02-18 | 2026-04-23 |
| Effectiveness of Opioid vs Pregabalin Plus Naproxen Sodium in Pain Management of Oral Cancer Patients Tramadol, Pregabalin + Naproxen Sodium - Oral Cancer, Oral Cavity Cancer | Not applicable | Enrolling by invitation | Mayo Hospital Lahore | 98 | 2026-02-01 | 2026-05-26 |
| A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC) Sacituzumab Govitecan, Cetuximab - Squamous Cell Carcinoma of Head and Neck, Sinus Cancer | Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 40 | 2025-07-02 | 2026-02-19 |
| Dysphagia and Quality of Life in Patients With Oral Squamous Cell Carcinoma Before and After Treatment Oral Cavity Cancer, Dysphagia | Not yet recruiting | University of Aarhus | 100 | 2024-06-01 | 2024-05-09 | |
| A Study of Concurrent Chemoradiation in Combination With or Without PD1 Inhibitor AB122 Adenosine 2a Receptor / Adenosine 2b Receptor Inhibitor AB928 Therapies in Locally Advanced Head and Neck Cancers Zimberelimab, Etrumadenant, Cisplatin - Head and Neck Cancer, Squamous Cell Carcinoma of Head and Neck | Phase 1 | Withdrawn | Jennifer Choe | 2023-12-31 | 2023-11-30 | |
| Evaluation of the Benefit of a New Surgical Procedure According to IDEAL Recommendations for ORL Cancer Patients: the External Pudendal Flap Used as a New Free Flap for Oral Cavity/Oropharyngeal Reconstruction to Limit Donor Site Sequelae Oropharyngeal or oral cavity reconstruction - Head and Neck Cancer, Oral Cavity Cancer | Not applicable | Recruiting | Institut Claudius Regaud | 40 | 2023-11-08 | 2025-09-15 |
| Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy ENDURE - Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma | Not applicable | Recruiting | Medical University of South Carolina | 532 | 2023-10-30 | 2025-12-11 |
| WORST PATTERN OF INVASION IN ORAL SQUAMOUS CELL CARCINOMA Biopsy Specimens Histopathology - Oral Cancer, Oral Cavity Cancer | Unknown | Armed Forces Institute of Pathology Rawalpindi | 81 | 2023-07-03 | 2023-07-03 | |
| The ENHANCE Study: Exercise and Nutrition in Head And Neck CancEr Survivors ENHANCE Intervention - Exercise and Nutrition, ENHANCE Intervention - Nutrition Only - Oral Cavity Cancer, Oropharynx Cancer | Not applicable | Completed | H. Lee Moffitt Cancer Center and Research Institute | 40 | 2023-04-06 | 2026-09-17 |
| Radial Forearm Donor Site Closure Split-Thickness Skin Graft for Radial Forearm Donor Site Closure, Hatchet Flap for Radial Forearm Donor Site Closure - Oral Cancer, Oral Cavity Cancer | Not applicable | Recruiting | University of British Columbia | 120 | 2023-02-01 | 2025-06-12 |
| Risk Factors Contributing to Oral Cancer in Patients at Dr. Hasan Sadikin General Hospital Bandung Oral Cavity Cancer | Completed | Universitas Padjadjaran | 107 | 2023-01-01 | 2024-11-15 | |
| Predictive Tools in Head and Neck Cancer Patients Undergoing Radiotherapy intensity modulated radiotherapy - Head and Neck Cancers, Head and Neck Cancers - Nasopharyngeal | Active not recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 915 | 2023-01-01 | 2025-02-04 | |
| Mandibular Reconstruction Preplanning (ViPMR) Virtual Surgical Planning (VSP), Free-Hand Surgery - Oral Cavity Cancer, Oral Cancer | Not applicable | Recruiting | University of British Columbia | 420 | 2022-10-15 | 2026-09-08 |
| Immune Biomarker Study for Head and Neck Cancer Sampling - Head and Neck Cancer, Oral Cavity Cancer | Recruiting | University of Erlangen-Nürnberg Medical School | 1100 | 2022-05-16 | 2023-05-17 | |
| Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis 100% Aloe Vera Juice, Magic Mouthwash, Salt and Baking soda rinse - Oral Cavity Cancer, Head and Neck Cancers - Tonsils | Phase 3 | Completed | Covenant Health Cancer Center | 100 | 2022-01-20 | 2024-10-10 |
| Gross Examinations Versus Frozen Section for Assessment of Surgical Margins in Oral Cancers Gross examination of the resection specimen, Frozen section - Oral Cavity Cancer | Not applicable | Recruiting | Dr.Pankaj Chaturvedi | 1206 | 2021-11-15 | 2025-04-11 |
Showing 20 of 41. Sign in to see all of them.
Mouth Neoplasms (41) · Oropharyngeal Neoplasms (20) · Laryngeal Neoplasms (15) · Head and Neck Neoplasms (12) · Hypopharyngeal Neoplasms (10) · Squamous Cell Carcinoma of Head and Neck (10) · Esophageal Neoplasms (4) · Nasopharyngeal Neoplasms (4) · Pharyngeal Neoplasms (4) · Anus Neoplasms (2) · Breast Neoplasms (2) · Carcinoma, Squamous Cell (2) · Deglutition Disorders (2) · Kidney Neoplasms (2) · Lip Neoplasms (2)
Mouth Diseases (41) · Neoplasms by Site (41) · Stomatognathic Diseases (41) · Neoplasms (39) · Head and Neck Neoplasms (29) · Otorhinolaryngologic Diseases (24) · Pharyngeal Diseases (24) · Otorhinolaryngologic Neoplasms (22) · Pharyngeal Neoplasms (18) · Respiratory Tract Diseases (16) · Respiratory Tract Neoplasms (16) · Laryngeal Diseases (14) · Neoplasms by Histologic Type (14) · Neoplasms, Glandular and Epithelial (14) · Carcinoma (12)
Cisplatin (3) · Radiation (3) · pembrolizumab (3) · Cetuximab (2) · Aminolevulinic Acid (1) · Biopsy (1) · Blood Specimen Collection (1) · Carboplatin (1) · Celecoxib (1) · Chemoradiotherapy (1) · Chemotherapy, Adjuvant (1) · Cyclophosphamide (1) · Dexamethasone (1) · Diagnosis, Oral (1) · Docetaxel (1)
Memorial Sloan Kettering Cancer Center (2) · Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University (2) · University of British Columbia (2) · A.T. Still University of Health Sciences (1) · AO Innovation Translation Center (1) · Armed Forces Institute of Pathology Rawalpindi (1) · Centre Hospitalier Universitaire, Amiens (1) · Christian von Buchwald (1) · Covenant Health Cancer Center (1) · Department of Medical Services Ministry of Public Health of Thailand (1) · Dr.Pankaj Chaturvedi (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Gustave Roussy, Cancer Campus, Grand Paris (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Institut Claudius Regaud (1)
United States (17) · France (4) · Canada (3) · China (2) · Denmark (2) · Germany (2) · India (2) · Pakistan (2) · Brazil (1) · Cyprus (1) · Czechia (1) · Indonesia (1) · Italy (1) · Norway (1) · Switzerland (1)
Adam Burr, MD, PhD (1) · Agung Adhariensya, MD (1) · Antoniu-Oreste Gostian, PD Dr. med. (1) · Assuntina Sacco, M.D. (1) · Benjamin Frey, PD Dr.-Ing. Dr. habil. med. (1) · C. Jillian Tsai, MD (1) · Christian Von Buchwald, MD, DMSc (1) · Clifton M Nichols, DDS (1) · Daniel Scaperoth, MD (1) · Einar Dale, MD PhD (1) · Ellen R. Gritz, PhD (1) · Evan M Graboyes, MD, MPH (1) · Jennifer Choe, MD, PhD (1)
PMID 31072197, PMID 32479189, PMID 33574900, PMID 33989559, PMID 34108183, PMID 36159069, PMID 40016641
R01CA282165 (1), R01DE024982 (1), R25CA057730 (1), R44CA275590 (1), U01CA279862 (1)