10 completed, 1 unknown. 11 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 11 | Completed 10, Unknown 1 |
Follow Opiate Dependence: new trials by email Literature Review of Opiate Dependence trials Research Report on Opiate Dependence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Pilot Study of Treating HCV at a Psychiatrist-staffed Outpatient Addiction Clinic sofosbuvir/velpatasvir - Hepatitis C, Chronic, Hepatitis C | Phase 4 | Completed | Community Research Initiative of New England | 11 | 2017-10-11 | 2021-05-13 |
| Multicentre Trial of Suboxone in Opiate-dependent Subjects in Taiwan Buprenorphine + naloxone (Suboxone) - Opiate Dependence | Phase 4 | Completed | Indivior Inc. | 127 | 2009-03-01 | 2012-11-30 |
| Buprenorphine Maintenance vs. Detoxification in Prescription Opioid Dependence Behavioral: Buprenorphine/naloxone maintenance (Mtn), Behavioral: Buprenorphine/naloxone detoxification (Dtx) - Opiate Dependence | Phase 4 | Completed | Yale University | 113 | 2008-07-01 | 2019-01-14 |
| A Randomized Acceptability and Safety Study of the Transfer From Subutex to Suboxone in Opioid- Dependent Subjects (Study P04843)(COMPLETED) Suboxone, Buprenorphine Hydrochloride + Naloxone, SCH 484, Subutex, Buprenorphine Hydrochloride, SCH 28444 - Opiate Dependence, Drug Dependence | Phase 4 | Completed | Indivior Inc. | 241 | 2008-03-01 | 2016-10-21 |
| A Randomized Acceptability and Safety Study of Suboxone Induction in Heroin Users (P05042)(COMPLETED) Suboxone (SCH 000484), Subutex (SCH 028444) - Opiate Dependence, Drug Dependence | Phase 4 | Completed | Merck Sharp & Dohme LLC | 188 | 2008-02-22 | 2017-07-02 |
| Preference for Subutex® (Buprenorphine) Versus Suboxone® (Buprenorphine/Naloxone) in Opioid Dependent Patients on Subutex® (Study P05094)(COMPLETED) buprenorphine, buprenorphine/naloxone - Opiate-related Disorders, Opiate Dependence | Phase 4 | Completed | Indivior Inc. | 60 | 2007-07-01 | 2023-03-20 |
| Integrating Buprenorphine Into HIV Treatment Integrating drug treatment into HIV services - Opiate Dependence, HIV Infections | Phase 4 | Unknown | Organization to Achieve Solutions in Substance Abuse (OASIS) | 60 | 2005-09-01 | 2005-10-25 |
| Counseling for Primary Care Office-based Buprenorphine Manual-guided Physician Management (PM), Physician Management (PM) combined with on-site manual-guided Cognitive Behavioral Therapy (CBT) - Opiate Dependence | Phase 4 | Completed | Yale University | 141 | 2005-08-01 | 2020-04-03 |
| Treatment of Polydrug-Using Opiate Dependents During Withdrawal Buprenorphine, Valproate - Opiate Dependence, Drug Dependence | Phase 4 | Completed | Sorlandet Hospital HF | 12 | 2003-02-01 | 2006-08-23 |
| Effects of Ketamine On Precipitated Opioid Withdrawal Under General Anaesthesia Ketamine - Opiate Dependence | Phase 4 | Completed | Vilnius University | 60 | 2003-02-01 | 2006-11-14 |
| Determine the Safety of a Sublingual Tablet Formulation of Buprenorphine and Naloxone by Extending the Combination Tablet Availability to Physicians in Office-Based Practice naloxone, buprenorphine - Opiate Dependence | Phase 4 | Completed | US Department of Veterans Affairs | 600 | 1999-08-01 | 2009-01-21 |
Opioid-Related Disorders (11) · Substance-Related Disorders (4) · HIV Infections (1) · Hepatitis C (1) · Hepatitis C, Chronic (1) · Substance Withdrawal Syndrome (1)
Chemically-Induced Disorders (11) · Mental Disorders (11) · Narcotic-Related Disorders (11) · Substance-Related Disorders (7) · Blood-Borne Infections (2) · Communicable Diseases (2) · Infections (2) · RNA Virus Infections (2) · Virus Diseases (2) · Chronic Disease (1) · Digestive System Diseases (1) · Disease Attributes (1) · Flaviviridae Infections (1) · Genital Diseases (1) · Hepatitis (1)
Buprenorphine (6) · Buprenorphine, Naloxone Drug Combination (4) · Naloxone (3) · Ketamine (1) · Valproic Acid (1) · sofosbuvir-velpatasvir drug combination (1)
Indivior Inc. (3) · Yale University (2) · Community Research Initiative of New England (1) · Merck Sharp & Dohme LLC (1) · Organization to Achieve Solutions in Substance Abuse (OASIS) (1) · Sorlandet Hospital HF (1) · US Department of Veterans Affairs (1) · Vilnius University (1)
United States (5) · Lithuania (1) · Norway (1) · Taiwan (1)
David A. Fiellin, MD (2) · Amy E Colson, MD MPH (1) · Diana L Sylvestre, MD (1) · Juozas Ivaskevicius, Prof. (1) · Oistein Kristensen, MD (1) · Ruth Finkelstein, ScD (1) · Shih-Ku Lin, MD (1) · Tomas Jovaisa, MD (1)
PMID 16401957, PMID 16963828, PMID 17107609, PMID 21749526, PMID 23260506, PMID 25330017, PMID 40833692
R01DA019511 (1), R01DA020576 (1)