5 recruiting, 3 completed, 3 unknown, 2 not yet recruiting. 5 Phase 2, 3 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Active not recruiting 1, Completed 1, Recruiting 1, Suspended 1, Unknown 1 |
| Not applicable | 3 | Unknown 2, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
Follow Oesophageal Adenocarcinoma: new trials by email Literature Review of Oesophageal Adenocarcinoma trials Research Report on Oesophageal Adenocarcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Breath Research Narrow Validation for Gastrointestinal Cancer Detection Oesophageal Squamous Cell Carcinoma, Oesophageal Adenocarcinoma | Recruiting | Imperial College London | 1000 | 2026-07-26 | 2026-10-22 | |
| Multicenter Prospective Cohort on Esophageal Endoscopic Submucosal Dissection Superficial Esophageal Cancer, Oesophageal Adenocarcinoma | Not yet recruiting | Société Française d'Endoscopie Digestive | 750 | 2026-02-01 | 2026-01-15 | |
| AUGMENTED RESPONSE OF VOLATILE BIOMARKERS IN THE ASSESSMENT OF OESOPHAGOGASTRIC CANCER (AROMA2) Breath Test - OESOPHAGO-GASTRIC CARCINOMA, Oesophageal Adenocarcinoma | Not yet recruiting | Imperial College London | 6000 | 2025-12-01 | 2025-12-03 | |
| Evaluation of Seismocardiography(SCG) for Assessing Fitness and Predicting Outcomes in Oesophageal Cancer Surgery Seismofit - Oesophageal Cancer, Oesophageal Adenocarcinoma | Recruiting | Guy's and St Thomas' NHS Foundation Trust | 164 | 2025-10-01 | 2026-09-14 | |
| Metformin as a Metabolic Intervention in Oesophageal Adenocarcinomas to Improve Response to Neoadjuvant Chemoradiotherapy Metformin - Oesophageal Adenocarcinoma, Tumor Microenvironment | Phase 2 | Recruiting | Amsterdam UMC, location VUmc | 14 | 2025-03-09 | 2025-07-10 |
| Longitudinal Assessment of Biomarkers After Oesophagogastric Cancer Surgery Biosample collection - Oesophageal Adenocarcinoma, Gastric Adenocarcinoma | Recruiting | Imperial College London | 100 | 2025-02-01 | 2025-02-19 | |
| Will a Pre-therapy Exercise Intervention Improve the Outcomes of Patients With Advanced Oesophageal Cancer? Low intensity exercise, High intensity exercise - Oesophageal Adenocarcinoma, T Cells | Not applicable | Recruiting | University of Surrey | 50 | 2024-04-26 | 2026-02-02 |
| Combination of Capmatinib + Spartalizumab in Advanced Oesogastric Adenocarcinoma Capmatinib, Spartalizumab - Oesophageal Adenocarcinoma, Gastric Adenocarcinoma | Phase 2 | Suspended | Assistance Publique - Hôpitaux de Paris | 90 | 2022-03-22 | 2023-02-03 |
| A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203) THOR-707, Pembrolizumab, Cetuximab - Oesophageal Squamous Cell Carcinoma, Gastric Cancer | Phase 2 | Completed | Sanofi | 138 | 2021-12-09 | 2025-09-24 |
| Blood-borne Assessment of Stromal Activation in Esophageal Adenocarcinoma to Guide Tocilizumab Therapy Tocilizumab 20 Mg/mL Intravenous Solution, Paclitaxel, Carboplatin - Esophageal Adenocarcinoma, Oesophageal Adenocarcinoma | Phase 2 | Active not recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 41 | 2021-01-27 | 2024-07-29 |
| M6620 Plus Standard Treatment in Oesophageal and Other Cancer M6620, Cisplatin, Capecitabine - Oesophageal Adenocarcinoma, Squamous Cell Carcinoma | Phase 1 | Completed | University of Oxford | 36 | 2018-12-04 | 2024-07-18 |
| Study Title: Peri-operative Immuno-Chemotherapy in Operable Oesophageal and Gastric Cancer FLOT-A - Gastric Adenocarcinoma, Oesophageal Adenocarcinoma | Phase 2 | Unknown | Royal Marsden NHS Foundation Trust | 44 | 2017-07-31 | 2023-02-21 |
| Prehabilitation of Patients With oEsophageal Malignancy Undergoing Peri-operative Treatment Exercise prehabilitation during chemotherapy before surgery - Oesophageal Adenocarcinoma, Chemotherapy Effect | Not applicable | Unknown | Guy's and St Thomas' NHS Foundation Trust | 66 | 2016-11-01 | 2018-08-13 |
| Exercise Prior to Oesophagectomy Pre-operative Exercise Programme (my-PEP), Home Exercise Programme (HEP) - Postoperative Complications (Cardiopulmonary), Oesophageal Adenocarcinoma | Not applicable | Unknown | University of East Anglia | 32 | 2016-09-01 | 2016-11-11 |
| Effects of Chemotherapy on Muscle Mass and Exercise Performance in Patients With Oesophageal Cancer. DEXA scan, Muscle biopsy, cardio-pulmonary exercise testing (CPEX) - Oesophageal Adenocarcinoma | Completed | University of Nottingham | 25 | 2011-10-01 | 2016-02-18 |
Adenocarcinoma Of Esophagus (15) · Esophageal Neoplasms (8) · Esophageal Squamous Cell Carcinoma (3) · Stomach Neoplasms (3) · Carcinoma, Hepatocellular (2) · Colorectal Neoplasms (2) · Motor Activity (2) · Adenocarcinoma (1) · Carcinoma, Squamous Cell (1) · Cholangiocarcinoma (1) · Liver Neoplasms (1) · Neoplasms (1) · Pancreatic Neoplasms (1) · Postoperative Complications (1)
Digestive System Diseases (10) · Digestive System Neoplasms (10) · Esophageal Diseases (10) · Gastrointestinal Diseases (10) · Gastrointestinal Neoplasms (10) · Head and Neck Neoplasms (10) · Neoplasms (10) · Neoplasms by Site (10) · Carcinoma (5) · Neoplasms by Histologic Type (5) · Neoplasms, Glandular and Epithelial (5) · Neoplasms, Squamous Cell (4) · Carcinoma, Squamous Cell (3) · Stomach Diseases (3) · Adenocarcinoma (2)
Absorptiometry, Photon (1) · Breath Tests (1) · Capecitabine (1) · Carboplatin (1) · Cetuximab (1) · Cisplatin (1) · High-Intensity Interval Training (1) · Metformin (1) · Paclitaxel (1) · Radiotherapy (1) · capmatinib (1) · pembrolizumab (1) · spartalizumab (1) · tocilizumab (1)
Imperial College London (3) · Guy's and St Thomas' NHS Foundation Trust (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Amsterdam UMC, location VUmc (1) · Assistance Publique - Hôpitaux de Paris (1) · Royal Marsden NHS Foundation Trust (1) · Sanofi (1) · Société Française d'Endoscopie Digestive (1) · University of East Anglia (1) · University of Nottingham (1) · University of Oxford (1) · University of Surrey (1)
United Kingdom (9) · France (3) · Netherlands (3) · Belgium (1) · Chile (1) · China (1) · Italy (1) · South Korea (1) · Spain (1) · United States (1)
Adam Frampton, PhD (1) · Andrew Davies, MBChBMDFRCS (1) · Andrew Davies, MD FRCS (1) · George Hanna (1) · George Hanna, MBBS; PhD; FRSC (1) · Hanneke W.M. van Laarhoven, MD, PhD (1) · Hanneke WM van Laarhoven, MD, PhD, PhD (1) · John Williams, MBChB, FFPMRCA, PhD (1) · Marco Gerlinger, MD, FRCP (1) · Maria A Hawkins, MD FRCR MRCP (1) · Sarah Derks, MD PhD (1)
PMID 32571298, PMID 35105604, PMID 35623069, PMID 38129525, PMID 42329347