15 completed, 2 unknown, 1 terminated. 4 Phase 1, 4 Phase 2, 3 Phase 3, 2 Not applicable, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 4 |
| Phase 2 | 4 | Completed 3, Unknown 1 |
| Phase 3 | 3 | Completed 2, Unknown 1 |
| Not applicable | 2 | Completed 2 |
| Early Phase 1 | 1 | Completed 1 |
Follow Nonneoplastic Condition: new trials by email Literature Review of Nonneoplastic Condition trials Research Report on Nonneoplastic Condition
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Biomarkers in Blood and Tissue Samples From Patients With Epstein-Barr Virus-Positive Hodgkin Lymphoma DNA analysis, RNA analysis, cytogenetic analysis - Lymphoma, Nonneoplastic Condition | Completed | Children's Oncology Group | 50 | 2011-12-01 | 2016-05-17 | |
| Vaccine Therapy in Preventing Human Papillomavirus Infection in Young HIV-Positive Male Patients Who Have Sex With Males quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine, laboratory biomarker analysis - Anal Cancer, Nonneoplastic Condition | Phase 2 | Completed | AIDS Malignancy Consortium | 149 | 2011-06-28 | 2020-08-11 |
| Biomarkers in Blood Samples From Patients With HIV Infection and Stage III or Stage IV Hodgkin Lymphoma Undergoing Chemotherapy DNA analysis, RNA analysis, laboratory biomarker analysis - Lymphoma, Nonneoplastic Condition | Terminated | AIDS Malignancy Consortium | 1 | 2011-06-01 | 2020-07-29 | |
| Infrared Coagulator Ablation or Observation in Preventing Anal Cancer in HIV-Positive Patients With Anal Neoplasia clinical observation, infrared photocoagulation therapy - Anal Cancer, Neoplasm of Uncertain Malignant Potential | Phase 3 | Completed | AIDS Malignancy Consortium | 120 | 2011-04-01 | 2020-08-04 |
| T-Lymphocyte Infusion or Standard Therapy in Treating Patients at Risk of Cytomegalovirus Infection After a Donor Stem Cell Transplant adoptive immunotherapy, alemtuzumab, in vitro-treated peripheral blood lymphocyte therapy - Graft Versus Host Disease, Nonneoplastic Condition | Phase 2 | Unknown | University Hospital Birmingham | 78 | 2009-09-01 | 2013-08-26 |
| Study of Blood and Tissue Samples From Patients With Aggressive Non-Hodgkin B-Cell Lymphoma or Hodgkin Lymphoma polymerase chain reaction, laboratory biomarker analysis - Lymphoma, Nonneoplastic Condition | Completed | AIDS Malignancy Consortium | 52 | 2009-08-01 | 2020-08-07 | |
| Vaccine Therapy in Preventing HPV in HIV-Positive Women in India quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine, DNA analysis, polymerase chain reaction - Cervical Cancer, Nonneoplastic Condition | Phase 1 | Completed | AIDS Malignancy Consortium | 150 | 2009-08-01 | 2024-03-19 |
| S0816 Fludeoxyglucose F 18-PET/CT Imaging and Combination Chemotherapy With or Without Additional Chemotherapy and G-CSF in Treating Patients With Stage III or Stage IV Hodgkin Lymphoma bleomycin sulfate, filgrastim, ABVD regimen - Lymphoma, Nonneoplastic Condition | Phase 2 | Completed | SWOG Cancer Research Network | 371 | 2009-07-01 | 2022-08-18 |
| Human Papilloma Virus Infection in HIV-Positive Indian Men Who Have Sex With Men DNA analysis, polymerase chain reaction, fluorescence activated cell sorting - Nonneoplastic Condition, Precancerous Condition | Completed | AIDS Malignancy Consortium | 302 | 2009-07-01 | 2015-10-05 | |
| Comparing Two Types of Swabs in Collecting Cell Samples for Anal Pap Tests and Human Papillomavirus Tests in Men Who Have Sex With Men Papanicolaou test - Anal Cancer, Nonneoplastic Condition | Not applicable | Completed | Jonsson Comprehensive Cancer Center | 48 | 2009-03-12 | 2020-08-03 |
| Prednisone or Dexamethasone in Newly Diagnosed, Previously Untreated Primary Immune Thrombocytopenic Purpura dexamethasone, prednisone, quality-of-life assessment - Nonneoplastic Condition | Phase 3 | Completed | Gruppo Italiano Malattie EMatologiche dell'Adulto | 150 | 2008-04-01 | 2017-02-20 |
| Rituximab and Prednisone as First-Line Therapy in Treating Patients With Immune Thrombocytopenic Purpura Rituximab, Prednisone - Nonneoplastic Condition | Early Phase 1 | Completed | Mayo Clinic | 22 | 2007-01-01 | 2014-10-17 |
| Vaccine Therapy in Preventing Cytomegalovirus in Healthy Participants PADRE-CMV fusion peptide vaccine, tetanus-CMV fusion peptide vaccine, agatolimod sodium - Nonneoplastic Condition | Phase 1 | Completed | City of Hope Medical Center | 68 | 2006-12-01 | 2012-06-25 |
| Vaccine Therapy, Incomplete Freund's Adjuvant, and GM-CSF in Treating Patients With HIV E1M184V peptide vaccine, incomplete Freund's adjuvant, sargramostim - Nonneoplastic Condition | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 40 | 2006-07-01 | 2012-05-02 |
| 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Systemic Mastocytosis tanespimycin - Chronic Myeloproliferative Disorders, Leukemia | Phase 2 | Completed | National Institutes of Health Clinical Center (CC) | 37 | 2006-05-01 | 2012-03-15 |
| Combination Chemotherapy Followed By Donor Stem Cell Transplant in Treating Patients With Hemophagocytic Lymphohistiocytosis anti-thymocyte globulin, busulfan, cyclophosphamide - Nonneoplastic Condition | Phase 3 | Unknown | Children's Cancer and Leukaemia Group | 288 | 2006-03-01 | 2013-09-17 |
| Vaccine Therapy in Treating Patients With Epstein-Barr Virus-Related Cancer EBNA1 C-terminal/LMP2 chimeric protein-expressing recombinant modified vaccinia Ankara vaccine, laboratory biomarker analysis, pharmacological study - Gastric Cancer, Head and Neck Cancer | Phase 1 | Completed | Cancer Research UK | 16 | 2005-03-01 | 2012-02-28 |
| Measuring Changes in Blood in Patients at High Risk of Cytomegalovirus Infection After Undergoing Donor Bone Marrow Transplant or Peripheral Blood Stem Cell Transplant ganciclovir, polymerase chain reaction, flow cytometry - Chronic Myeloproliferative Disorders, Leukemia | Not applicable | Completed | City of Hope Medical Center | 100 | 2000-01-01 | 2015-06-08 |
HIV Infections (9) · Lymphoma (7) · Hodgkin Disease (6) · Precancerous Conditions (6) · Papillomavirus Infections (5) · Burkitt Lymphoma (4) · Lymphoma, Large-Cell, Immunoblastic (4) · Anus Neoplasms (3) · Cytomegalovirus Infections (3) · Lymphoma, Large B-Cell, Diffuse (3) · Epstein-Barr Virus Infections (2) · Leukemia (2) · Leukemia, Hairy Cell (2) · Leukemia, Lymphocytic, Chronic, B-Cell (2) · Lymphohistiocytosis, Hemophagocytic (2)
Immune System Diseases (16) · Infections (15) · Virus Diseases (15) · DNA Virus Infections (12) · Neoplasms (12) · Hemic and Lymphatic Diseases (10) · Tumor Virus Infections (10) · Blood-Borne Infections (9) · Communicable Diseases (9) · Genital Diseases (9) · Immunologic Deficiency Syndromes (9) · Lentivirus Infections (9) · Pathologic Processes (9) · Pathological Conditions, Signs and Symptoms (9) · RNA Virus Infections (9)
Polymerase Chain Reaction (6) · Flow Cytometry (3) · Prednisone (3) · Cyclophosphamide (2) · Dexamethasone (2) · Etoposide (2) · Ganciclovir (2) · Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18 (2) · Peripheral Blood Stem Cell Transplantation (2) · ABVD protocol (1) · Alemtuzumab (1) · Antilymphocyte Serum (1) · Biopsy (1) · Bleomycin (1) · Blotting, Western (1)
AIDS Malignancy Consortium (6) · City of Hope Medical Center (2) · National Institutes of Health Clinical Center (CC) (2) · Cancer Research UK (1) · Children's Cancer and Leukaemia Group (1) · Children's Oncology Group (1) · Gruppo Italiano Malattie EMatologiche dell'Adulto (1) · Jonsson Comprehensive Cancer Center (1) · Mayo Clinic (1) · SWOG Cancer Research Network (1) · University Hospital Birmingham (1)
United States (11) · United Kingdom (3) · India (1) · Italy (1) · Puerto Rico (1)
Joel Palefsky, MD (3) · John A. Zaia, MD (2) · Antonio T. Fojo, MD, PhD (1) · Ashok Row Kavi (1) · Dilip Mathai, MD (1) · Dorothy Wiley, Ph.D. RN (1) · Frederick Chen, MD (1) · John W. Mellors, MD (1) · Kathleen M. Wyvill, BSN, RN (1) · Kim E. Nichols, MD, BA (1) · Maria Gabriella Mazzucconi, MD (1) · N. Kumarasamy, MD (1) · Neil M Stevens, MD (1) · Nina Wagner-Johnston, MD (1) · Oliver W. Press, MD, PhD (1)
PMID 21719601, PMID 22402037, PMID 23595039, PMID 28508728, PMID 30060087, PMID 30658128, PMID 30723079, PMID 31331918, PMID 38231017, PMID 40135712
U01CA121947 (5), P30CA033572 (2), P30CA015083 (1), R01AI058148 (1), R01CA077544 (1), U10CA032102 (1)