6 completed, 4 unknown, 2 terminated, 1 active not recruiting. 11 Phase 3, 3 Phase 2, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 4, Unknown 3, Terminated 2, Active not recruiting 1, Withdrawn 1 |
| Phase 2 | 3 | Completed 3 |
| Phase 4 | 2 | Recruiting 1, Unknown 1 |
Follow this drug Literature Review of ABVD protocol trials Research Report on ABVD protocol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pediatric Hodgkin Lymphoma Treatment Trial With Low Cumulative Doses of Chemotherapy Agents and Reduced Radiation. No radiotherapy if CR at the end of chemotherapy., Low risk with complete early response after two cycles of ABVD chemotherapy schedule. Only one more ABVD course is delivered., Low risk with partial remisssion after 4 cycles of ABVD chemotherapy schedule. Two ESHAP courses are delivered. - Pediatric Hodgkin's Disease | Phase 4 | Recruiting | Hospital JP Garrahan | 500 | 2017-10-06 | 2025-04-16 |
| Very Early FDG-PET/CT-response Adapted Therapy for Advanced Hodgkin Lymphoma (H11) ABVD + FDG-PET/CT Scan treatment adaptation, BEACOPPesc - Hodgkin Lymphoma | Phase 3 | Withdrawn | European Organisation for Research and Treatment of Cancer - EORTC | 2013-05-01 | 2021-02-15 | |
| HD17 for Intermediate Stage Hodgkin Lymphoma BEACOPPescalated (Bleomycin, Etoposide, Adriamycin, Cyclophosphamide, Vincristine, Procarbazine, Prednisone), ABVD (Adriamycin, Bleomycin, Vinblastine, Dacarbazine), 30Gy IF-RT (Involved-Field Radiotherapy) - Hodgkin Lymphoma | Phase 3 | Completed | University of Cologne | 1100 | 2012-01-13 | 2020-04-06 |
| Study Evaluating the Effect of R-mabHDI in Lymphocytic Predominant Hodgkin's Lymphoma R-mabHDI and ABVD, ABVD - Hodgkin's Lymphoma | Phase 3 | Unknown | American Scitech International | 1200 | 2011-07-01 | 2011-07-20 |
| HD16 for Early Stage Hodgkin Lymphoma ABVD (Adriamycin, Bleomycin, Vincristine, Dacarbazine), 20 Gy IFRT (Involved Field Radiotherapy) - Hodgkin Lymphoma | Phase 3 | Unknown | University of Cologne | 1150 | 2009-11-01 | 2020-11-04 |
| R-ABVD vs ABVD-RT in Early Stage Hodgkin's Lymphoma Rituximab, Involved field irradiation - Hodgkin Lymphoma | Phase 3 | Terminated | Fondazione Michelangelo | 112 | 2009-09-01 | 2021-08-19 |
| S0816 Fludeoxyglucose F 18-PET/CT Imaging and Combination Chemotherapy With or Without Additional Chemotherapy and G-CSF in Treating Patients With Stage III or Stage IV Hodgkin Lymphoma bleomycin sulfate, filgrastim, ABVD regimen - Lymphoma, Nonneoplastic Condition | Phase 2 | Completed | SWOG Cancer Research Network | 371 | 2009-07-01 | 2022-08-18 |
| High-dose Chemotherapy and Stem Cell Transplantation, in Patients PET-2 Positive, After 2 Courses of ABVD and Comparison of RT Versus no RT in PET-2 Negative Patients ABVD, ABVD and Radiotherapy - Hodgkin's Lymphoma | Phase 2 / Phase 3 | Completed | Fondazione Italiana Linfomi - ETS | 520 | 2008-09-01 | 2018-02-08 |
| Three Different Therapy Regimens in Treating Patients With Previously Untreated Hodgkin Lymphoma bleomycin sulfate, ABVD regimen, carmustine - Lymphoma | Phase 3 | Terminated | French Innovative Leukemia Organisation | 442 | 2008-05-01 | 2016-09-16 |
| Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Stage III or Stage IV Hodgkin's Lymphoma bleomycin sulfate, filgrastim, pegfilgrastim - Lymphoma | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 552 | 2002-08-01 | 2025-08-05 |
| Combination Chemotherapy in Treating Patients With Previously Untreated Advanced Hodgkin's Lymphoma bleomycin sulfate, ABVD regimen, Stanford V regimen - Lymphoma | Phase 3 | Unknown | Mount Vernon Cancer Centre at Mount Vernon Hospital | 850 | 2001-10-01 | 2013-09-20 |
| Optimization of the Primary Therapy for Patients With Hodgkin's Disease and Evaluation of PET Combined chemotherapy (ABVD, BACOPP-D), Radiation therapy - Hodgkin Disease | Phase 4 | Unknown | University Hospital Carl Gustav Carus | 300 | 2000-05-01 | 2005-12-29 |
| Combination Chemotherapy and Radiation Therapy in Treating Children With Previously Untreated Stage II, Stage III, or Stage IV Hodgkin's Disease bleomycin sulfate, filgrastim, ABVD regimen - Lymphoma | Phase 2 | Completed | Children's Oncology Group | 99 | 1999-10-01 | 2014-02-26 |
| Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Hodgkin's Lymphoma bleomycin sulfate, ABVD regimen, BEACOPP regimen - Lymphoma | Phase 3 | Active not recruiting | European Organisation for Research and Treatment of Cancer - EORTC | 1649 | 1998-10-01 | 2025-08-05 |
| Combination Chemotherapy in Treating Patients With Advanced Hodgkin's Disease bleomycin sulfate, ABVD regimen, chlorambucil - Lymphoma | Phase 3 | Completed | Medical Research Council | 800 | 1998-06-01 | 2013-12-04 |
Hodgkin Disease (14) · Lymphoma (7) · HIV Infections (1)
European Organisation for Research and Treatment of Cancer - EORTC (3) · University of Cologne (2) · American Scitech International (1) · Children's Oncology Group (1) · Fondazione Italiana Linfomi - ETS (1) · Fondazione Michelangelo (1) · French Innovative Leukemia Organisation (1) · Hospital JP Garrahan (1) · Medical Research Council (1) · Mount Vernon Cancer Centre at Mount Vernon Hospital (1) · SWOG Cancer Research Network (1) · University Hospital Carl Gustav Carus (1)
United States (4) · France (3) · Germany (3) · Italy (3) · United Kingdom (3) · Australia (2) · Belgium (2) · Canada (2) · Netherlands (2) · Poland (2) · Spain (2) · Argentina (1) · Croatia (1) · Czechia (1) · Denmark (1)
Andreas Engert, Prof. (2) · Alessandro Levis, MD (1) · Alessandro M Gianni, MD (1) · Anna Sureda (1) · Barry W. Hancock, MD (1) · Bengt Glimelius, MD (1) · Berthe Aleman (1) · Christian Gisselbrecht, MD (1) · Christophe Ferme (1) · David C. Linch (1) · David Ma, MD (1) · Delphine Senecal (1) · Devinder Gill, MD (1) · E.M. Noordijk, MD (1)
PMID 40135712, PMID 30010775, PMID 41074963, PMID 16314615, PMID 21079154, PMID 25964643, PMID 26884559, PMID 27114593, PMID 28601705, PMID 29229324, PMID 30723079, PMID 31331918, PMID 31498753, PMID 33539742, PMID 34597375, PMID 35717166, PMID 37644732, PMID 42848781
2004 (1), 2009 (1), U10CA032102 (1)