2 completed, 2 terminated, 1 unknown. 3 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 2, Terminated 1 |
| Phase 2 | 2 | Terminated 1, Unknown 1 |
Follow Non-small Cell Lung Cancers: new trials by email Literature Review of Non-small Cell Lung Cancers trials Research Report on Non-small Cell Lung Cancers
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of PRT3789 in Combination With Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation PRT3789, pembrolizumab - Advanced Solid Tumor, Esophageal Cancer | Phase 2 | Terminated | Prelude Therapeutics Incorporated | 6 | 2025-06-03 | 2026-02-02 |
| Phase Ib Trial of the KRAS G12C Inhibitor Adagrasib (MRTX849) in Combination With the PARP Inhibitor Olaparib in Patients With KRAS G12C Mutated Advanced Solid Tumors, With a Focus on Gynecological, Breast, Pancreatic and KEAP1 Mutated Non-small Cell Lung Cancers Adagrasib, Olaparib - Advanced Solid Tumor, Non-small Cell Lung Cancers | Phase 1 | Terminated | M.D. Anderson Cancer Center | 1 | 2024-01-30 | 2026-04-09 |
| PRT3789 Monotherapy and in Combo w/Docetaxel in Participants w/Advanced or Metastatic Solid Tumors w/SMARCA4 Mutation PRT3789, Docetaxel - Advanced Solid Tumor, Metastatic Solid Tumor | Phase 1 | Completed | Prelude Therapeutics Incorporated | 135 | 2023-05-02 | 2025-10-16 |
| A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors PRT3645 - Breast Cancer, Glioblastoma | Phase 1 | Completed | Prelude Therapeutics Incorporated | 22 | 2022-12-27 | 2024-07-01 |
| Safety of Pentoxifylline and Vitamin E With Stereotactic Ablative Radiotherapy (SABR) in Non-small Cell Lung Cancers stereotactic ablative radiotherapy (SABR), Pentoxifylline - Non-small Cell Lung Cancers | Phase 2 | Unknown | University of Louisville | 59 | 2013-10-01 | 2024-02-07 |
Neoplasm Metastasis (2) · Breast Neoplasms (1) · Endometrial Neoplasms (1) · Esophageal Neoplasms (1) · Glioblastoma (1) · Mesothelioma, Malignant (1) · Sarcoma (1) · Squamous Cell Carcinoma of Head and Neck (1)
Neoplasms (3) · Head and Neck Neoplasms (2) · Neoplasms by Site (2) · Neoplastic Processes (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Adenoma (1) · Astrocytoma (1) · Breast Diseases (1) · Carcinoma (1) · Carcinoma, Squamous Cell (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Esophageal Diseases (1) · Female Urogenital Diseases (1)
Docetaxel (1) · Pentoxifylline (1) · adagrasib (1) · olaparib (1) · pembrolizumab (1)
Prelude Therapeutics Incorporated (3) · M.D. Anderson Cancer Center (1) · University of Louisville (1)
United States (5) · Singapore (2) · Spain (2) · France (1) · Netherlands (1)
Neal E Dunlap, MD (1) · Timothy Yap, MD (1)