21 unknown. 21 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 21 | Unknown 21 |
| Phase 1 | 4 | Unknown 4 |
Follow Neuroblastoma: new trials by email Literature Review of Neuroblastoma trials Research Report on Neuroblastoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Therapeutic Iobenguane (131-I) and Vorinostat for Recurrent or Progressive High-Risk Neuroblastoma Subjects 131I-MIBG, 131-MIBG + Vorinostat - Neuroblastoma, Neuroectodermal Tumors | Phase 2 | Unknown | Jubilant DraxImage Inc. | 60 | 2019-10-21 | 2023-02-16 |
| Immunotherapy of Neuroblastoma Patients Using a Combination of Anti-GD2 and NK Cells Anti-GD2 in combination with NK cells - Neuroblastoma Recurrent | Phase 1 / Phase 2 | Unknown | National University Hospital, Singapore | 5 | 2017-10-03 | 2018-03-30 |
| Anti-angiogenetic Therapy With Radiotherapy for Pediatric Neuroblastoma Endostar, 21.6Gy/12Fx to the tumor bed and 36Gy/20Fx to the tumor - Neuroblastoma | Phase 2 | Unknown | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | 60 | 2015-11-01 | 2016-06-14 |
| Response-based Treatment of High-risk Neuroblastoma Cisplatin, Doxorubicin, Etoposide - Newly Diagnosed High Risk Neuroblastoma | Phase 2 | Unknown | Samsung Medical Center | 54 | 2015-04-01 | 2016-05-24 |
| Phase II Study of Monoclonal Antibody ch14.18/CHO Continuous Infusion in Patients With Primary Refractory or Relapsed Neuroblastoma dinutuximab beta - Neuroblastoma | Phase 2 | Unknown | University Medicine Greifswald | 40 | 2015-03-27 | 2021-10-04 |
| Activated T Cells Armed With GD2 Bispecific Antibody in Children and Young Adults With Neuroblastoma and Osteosarcoma IL-2, GD2Bi-aATC, GM-CSF - Disseminated Neuroblastoma, Recurrent Neuroblastoma | Phase 1 / Phase 2 | Unknown | University of Virginia | 40 | 2014-11-01 | 2019-01-29 |
| Haploidentical Stem Cell Transplantation and NK Cell Therapy in Patients With High-risk Solid Tumors haploidentical stem cell transplantation and NK cell therapy - Neuroblastoma, Ewing Sarcoma | Phase 2 | Unknown | Samsung Medical Center | 12 | 2013-05-01 | 2018-09-18 |
| Long Term Continuous Infusion ch14.18/CHO Plus s.c. Aldesleukin (IL-2) ch14.18/CHO, Aldesleukin, Isotretinoin - Neuroblastoma | Phase 1 / Phase 2 | Unknown | St. Anna Kinderkrebsforschung | 288 | 2012-01-01 | 2020-07-14 |
| Haplo-identical Hematopoietic Stem Cell Transplantation Following Reduced-intensity Conditioning in Children With Neuroblastoma Busulfan - Fludarabine - TBI - Neuroblastoma | Phase 2 | Unknown | University Hospital, Clermont-Ferrand | 10 | 2011-09-01 | 2011-01-19 |
| 131I-MIBG With Myeloablative Chemotherapy and Autologous Stem Cell Transplantation for the Treatment of High-risk Neuroblastoma 131I-MIBG , Etoposide, Melphalan, Carboplatin, Autologous Peripheral Stem Cell Transplantation - Neuroblastoma | Phase 1 / Phase 2 | Unknown | Tehran University of Medical Sciences | 10 | 2008-09-01 | 2012-06-04 |
| Topotecan, Vincristine, and Doxorubicin in Treating Young Patients With Refractory Stage 4 Neuroblastoma filgrastim, doxorubicin hydrochloride, topotecan hydrochloride - Neuroblastoma | Phase 2 | Unknown | Children's Cancer and Leukaemia Group | 63 | 2008-03-01 | 2013-09-17 |
| External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases indinavir sulfate, ritonavir, radiation therapy - Cancer | Phase 2 | Unknown | Oncology Institute of Southern Switzerland | 60 | 2007-09-01 | 2013-08-12 |
| Observation of Young Patients With Localized Neuroblastoma Who Have Undergone Surgery Only clinical observation - Long-term Effects Secondary to Cancer Therapy in Children, Neuroblastoma | Phase 2 | Unknown | Children's Cancer and Leukaemia Group | 140 | 2004-12-01 | 2013-09-20 |
| Umbilical Cord Blood for Stem Cell Transplantation in Treating Young Patients With Malignant or Nonmalignant Diseases anti-thymocyte globulin, busulfan, cyclophosphamide - Childhood Langerhans Cell Histiocytosis, Fanconi Anemia | Phase 2 | Unknown | Milton S. Hershey Medical Center | 25 | 2003-09-01 | 2014-01-10 |
| Study of Vinorelbine and Cyclofosfamide Among Patients With Refractory Tumours or in Relapse Vinorelbine, cyclofosfamide - Rhabdomyosarcomas, Neoplasms, Connective and Soft Tissue | Phase 2 | Unknown | Gustave Roussy, Cancer Campus, Grand Paris | 210 | 2003-06-01 | 2006-09-08 |
| Light-Emitting Diode Therapy in Preventing Mucositis in Children Receiving Chemotherapy With or Without Radiation Therapy Before Bone Marrow Transplantation management of therapy complications, pain therapy - Chronic Myeloproliferative Disorders, Kidney Cancer | Phase 2 | Unknown | Medical College of Wisconsin | 80 | 2002-01-01 | 2013-09-20 |
| Chemotherapy and Surgery Followed by Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Neuroblastoma filgrastim, busulfan, cisplatin - Neuroblastoma | Phase 2 | Unknown | Children's Cancer and Leukaemia Group | 1999-04-01 | 2013-08-07 | |
| Interleukin-2 in Treating Children With Stage IV Neuroblastoma Who Have Received Induction Therapy and Peripheral Stem Cell Transplantation aldesleukin - Neuroblastoma | Phase 2 | Unknown | St. Anna Kinderkrebsforschung | 25 | 1997-03-01 | 2013-09-17 |
| Surgery in Treating Patients With Neuroblastoma surgical procedure - Neuroblastoma | Phase 2 | Unknown | Societe Internationale d'Oncologie Pediatrique | 210 | 1994-12-01 | 2013-08-26 |
| Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors carboplatin, cisplatin, cyclophosphamide - Brain and Central Nervous System Tumors, Neuroblastoma | Phase 2 | Unknown | Children's Cancer and Leukaemia Group | 50 | 1992-06-01 | 2013-09-20 |
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Recurrence (4) · Burkitt Lymphoma (3) · Dendritic Cell Sarcoma, Interdigitating (3) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (3) · Sarcoma (3) · Leukemia (2) · Leukemia, Lymphocytic, Chronic, B-Cell (2) · Leukemia, Myeloid, Chronic-Phase (2) · Lymphoma (2) · Myelodysplastic Syndromes (2) · Neoplasms (2) · Osteosarcoma (2) · Rhabdomyosarcoma (2) · Sarcoma, Ewing (2)
Neoplasms by Histologic Type (21) · Neoplasms, Germ Cell and Embryonal (21) · Neoplasms, Glandular and Epithelial (21) · Neoplasms, Nerve Tissue (21) · Neoplasms, Neuroepithelial (21) · Neuroectodermal Tumors, Primitive (21) · Neuroectodermal Tumors (20) · Neuroectodermal Tumors, Primitive, Peripheral (20) · Neoplasms (19) · Disease Attributes (5) · Pathologic Processes (5) · Pathological Conditions, Signs and Symptoms (5) · Neoplasms, Connective and Soft Tissue (4) · Chronic Disease (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3)
3-Iodobenzylguanidine (4) · Cyclophosphamide (4) · Radiotherapy (4) · Carboplatin (3) · Cisplatin (3) · Doxorubicin (3) · Etoposide (3) · Interleukin-2 (3) · Melphalan (3) · Vincristine (3) · aldesleukin (3) · Busulfan (2) · Filgrastim (2) · Isotretinoin (2) · Analgesia (1)
Children's Cancer and Leukaemia Group (4) · Samsung Medical Center (2) · St. Anna Kinderkrebsforschung (2) · Gustave Roussy, Cancer Campus, Grand Paris (1) · Jubilant DraxImage Inc. (1) · Medical College of Wisconsin (1) · Milton S. Hershey Medical Center (1) · National Center for Research Resources (NCRR) (1) · National University Hospital, Singapore (1) · Oncology Institute of Southern Switzerland (1) · Societe Internationale d'Oncologie Pediatrique (1) · Tehran University of Medical Sciences (1) · University Hospital, Clermont-Ferrand (1) · University Medicine Greifswald (1) · University of Virginia (1)
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Jean Marie Michon, MD (2) · Ki Woong Sung, MD, PhD (2) · Bruno De Bernardi, MD (1) · D. Valteau-Couanet (1) · Dario Campana, MD, PhD (1) · Guy Makin, MD, PhD (1) · Harry T. Whelan, MD (1) · Holger Lode, MD, PhD (1) · Holger Lode, Professor (1) · Ilja Ciernik, MD (1) · Janice A. Kohler, MD, FRCP (1) · Kenneth G. Lucas, MD (1) · Maxim Yankelevich (1) · Melda Dolan (1)
2009 (1), 2014 (1), P30CA022453 (1)