8 suspended. 8 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 8 | Suspended 8 |
| Phase 2 | 2 | Suspended 2 |
Follow Neoplasm Metastasis: new trials by email Literature Review of Neoplasm Metastasis trials Research Report on Neoplasm Metastasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases Azeliragon, Stereotactic radiosurgery, Corticosteroid - Cancer, Metastasis | Phase 1 / Phase 2 | Suspended | Baptist Health South Florida | 46 | 2023-11-17 | 2026-06-16 |
| A Study of NPX267 for Subjects With Solid Tumors Known to Express HHLA2/B7-H7 NPX267 - Metastatic Malignant Neoplasm | Phase 1 | Suspended | NextPoint Therapeutics, Inc. | 131 | 2023-07-21 | 2025-06-27 |
| Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer Vactosertib, Fludarabine Phosphate, Cyclophosphamide - Colorectal Cancer, Hematologic Malignancy | Phase 1 | Suspended | David Wald | 12 | 2022-09-09 | 2026-07-14 |
| Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors BET Bromodomain Inhibitor ZEN-3694, Biopsy Procedure, Biospecimen Collection - Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm | Phase 1 | Suspended | National Cancer Institute (NCI) | 66 | 2022-02-02 | 2026-08-17 |
| A Cancer Vaccine (Labvax 3(22)-23) and GM-CSF Alone or in Combination With Pembrolizumab for the Treatment of Advanced Stage Adenocarcinoma Antineoplastic Vaccine, Sargramostim, Pembrolizumab - Advanced Adenocarcinoma, Advanced Malignant Solid Neoplasm | Phase 1 / Phase 2 | Suspended | University of California, Davis | 77 | 2021-01-13 | 2026-06-29 |
| Alpha-TEA and Trastuzumab for the Treatment of Refractory HER2+ Metastatic Breast Cancer Alpha-tocopheryloxyacetic Acid, Trastuzumab - Anatomic Stage IV Breast Cancer AJCC v8, HER2 Positive Breast Carcinoma | Phase 1 | Suspended | Veana Therapeutics | 24 | 2020-04-08 | 2024-07-10 |
| A Phase 1a/1b Study to Evaluate the Safety of EZN-4176, in Adult Patients With Castration-Resistant Prostate Cancer EZN-4176 - Prostatic Neoplasm | Phase 1 | Suspended | Enzon Pharmaceuticals, Inc. | 150 | 2011-03-01 | 2012-12-18 |
| A Safety Study to Determine the Maximum Tolerated Dose of Elesclomol Sodium in Patients With Solid Tumors Elesclomol Sodium - Metastatic Solid Tumors | Phase 1 | Suspended | Synta Pharmaceuticals Corp. | 30 | 2009-01-01 | 2009-03-09 |
Adenocarcinoma (2) · Colorectal Neoplasms (2) · Neoplasms (2) · Prostatic Neoplasms (2) · Brain Neoplasms (1) · Breast Neoplasms (1) · Bulbo-Spinal Atrophy, X-Linked (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Renal Cell (1) · Carcinoma, Transitional Cell (1) · Cholangiocarcinoma (1) · Endometrial Neoplasms (1) · Esophageal Neoplasms (1) · Hematologic Neoplasms (1)
Neoplastic Processes (8) · Pathologic Processes (8) · Pathological Conditions, Signs and Symptoms (8) · Neoplasms (6) · Neoplasms by Site (6) · Neoplasms by Histologic Type (4) · Carcinoma (3) · Genital Diseases (3) · Neoplasms, Glandular and Epithelial (3) · Urogenital Diseases (3) · Urogenital Neoplasms (3) · Breast Diseases (2) · Central Nervous System Diseases (2) · Colonic Diseases (2) · Digestive System Diseases (2)
2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid (1) · 5'-ACCaagtttcttcAGC-3' (1) · Acetic Acid (1) · Adrenal Cortex Hormones (1) · Antibodies, Monoclonal (1) · Biopsy (1) · CTLA-4 Antigen (1) · Cancer Vaccines (1) · Colony-Stimulating Factors (1) · Cyclophosphamide (1) · Dexamethasone (1) · IL32 protein, human (1) · Interleukin-2 (1) · Ipilimumab (1) · Magnetic Resonance Spectroscopy (1)
Baptist Health South Florida (1) · David Wald (1) · Enzon Pharmaceuticals, Inc. (1) · National Cancer Institute (NCI) (1) · NextPoint Therapeutics, Inc. (1) · Synta Pharmaceuticals Corp. (1) · University of California, Davis (1) · Veana Therapeutics (1)
United States (8) · United Kingdom (1)
Aby Buchbinder, MD (1) · Benjamin Tomlinson, MD (1) · Daniel Danila, MD (1) · Haider S Mahdi (1) · Johann de Bono, MD (1) · Leena Gandhi, MD, PhD (1) · Minesh Mehta, M.D. (1) · Tianhong Li (1) · William Gwin, MD (1)
P30CA093373 (1), UM1CA186690 (1)