7 completed, 1 enrolling by invitation, 1 recruiting, 1 suspended. 8 Not applicable, 2 Phase 4, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 5, Enrolling by invitation 1, Suspended 1, Unknown 1 |
| Phase 4 | 2 | Completed 1, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lidocaine Patch for Epidural Placement Pain in Laboring Women Lidocaine patch 4%, Placebo Patch, 1% Lidocaine Skin Wheal - Needle Phobia | Phase 3 | Recruiting | Ohio State University | 66 | 2026-10-07 | 2026-10-23 |
| Use of Augmented Reality and Virtual Reality During Cognitive Behavioral Therapy for Needle Phobia Mixed reality (XR) Exposure Therapy - Needle Phobia, Virtual Reality | Not applicable | Enrolling by invitation | Stanford University | 20 | 2026-09-01 | 2026-08-18 |
| Determining Whether There is a Change in Time Taken to Return to Homeostatic Temperature With Repeated Exposure to a Cold Stressor Metal block - Needle Phobia, Needle Fear | Not applicable | Unknown | The Whiteley Clinic | 5 | 2023-02-01 | 2023-02-06 |
| Assessment of Pain, Anxiety and Efficiency of NumBee Compared to Traditional Local Anesthetic Syringe dental syringe ( NumBee), Traditional dental syringe - Dental Phobia, Dental Anxiety | Not applicable | Completed | Duaa Kamal Naji | 30 | 2022-03-15 | 2023-06-12 |
| Needle-free Dental Anesthesia Meso-Jet, 2% lidocaine(xylocaine), Needle,2% lidocaine(xylocaine) - Anesthesia, Local, Needle Phobia | Not applicable | Suspended | McGill University Health Centre/Research Institute of the McGill University Health Centre | 30 | 2019-07-18 | 2021-09-05 |
| Pain Perception of Needle-free System Needle-free injection - Pain, Needle Phobia | Not applicable | Completed | Tokat Gaziosmanpasa University | 56 | 2019-03-11 | 2020-12-23 |
| Pain Perception With a Comfort-ın Jet Injection and Conventional Dental Injection Needle-free injection - Pain, Local Infiltration | Not applicable | Completed | Tokat Gaziosmanpasa University | 94 | 2018-06-20 | 2020-12-23 |
| Efficacy of Shotblocker in Spinal Needle Related Pain Shotblocker, Placebo - Needle Phobia, Spinal Anesthesia | Not applicable | Completed | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | 88 | 2018-01-01 | 2019-10-25 |
| Comparison of Routine IM Influenza Immunization and Administration by Jet-injector (Med-Jet H4™) in Healthy Young Adults Fluviral influenza vaccine - Needle Phobia | Phase 4 | Completed | brian.ward | 80 | 2017-05-12 | 2018-08-15 |
| The Effect of Acupressure (GB30) on Ventrogluteal Intramuscular Injection Pain Acupressure - Acute Pain, Injection | Not applicable | Completed | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | 72 | 2016-09-01 | 2018-06-13 |
| Effect of Including Synera® in Discussions on Dialysis Access Conversion in Patients With Needle Phobias Enhanced Needle Phobia Intervention, Standard Needle Phobia Intervention - Needle Phobia, Phobic Disorders | Phase 4 | Terminated | Davita Clinical Research | 10 | 2014-04-01 | 2016-08-16 |
| The Efficacy of EMLA Cream vs. Synera Patch for Pain Reduction During Venipuncture in Children EMLA Cream, Synera Patch - Pain, Needle Phobia | Phase 2 | Completed | Montefiore Medical Center | 100 | 2007-06-01 | 2018-08-31 |
Pain (5) · Anxiety Disorders (2) · Acute Pain (1) · Common Cold (1) · Iatrophobia (1) · Influenza, Human (1) · Phobic Disorders (1) · Toothache (1)
Neurologic Manifestations (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Mental Disorders (3) · Infections (2) · RNA Virus Infections (2) · Respiratory Tract Diseases (2) · Respiratory Tract Infections (2) · Virus Diseases (2) · Anxiety Disorders (1) · Facial Pain (1) · Orthomyxoviridae Infections (1) · Pain (1) · Picornaviridae Infections (1) · Stomatognathic Diseases (1)
Dental Health Services (2) · Acupressure (1) · Implosive Therapy (1) · Lidocaine (1) · Lidocaine, Prilocaine Drug Combination (1)
Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey (2) · Tokat Gaziosmanpasa University (2) · Davita Clinical Research (1) · Duaa Kamal Naji (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Montefiore Medical Center (1) · Ohio State University (1) · Stanford University (1) · The Whiteley Clinic (1) · brian.ward (1)
United States (4) · Turkey (Türkiye) (3) · Canada (2) · Iraq (1) · United Kingdom (1)
Halenur Altan, Assoc Prof. (2) · Aaron Lulla, MD, PhD (1) · Brian J Ward, MD (1) · Catherine C Skae, MD (1) · Duaa K Naji (1) · Faleh Tamimi, Ph.D. (1) · Mahesh Krishnan, MD, MPH, MBA (1) · Mark S Whiteley, MS FRCS (Gen) MB BS (1)