4 recruiting, 3 completed. 3 Not applicable, 2 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 2, Recruiting 1 |
| Phase 2 | 2 | Recruiting 2 |
| Phase 3 | 1 | Recruiting 1 |
Follow Natriuretic Peptides: new trials by email Literature Review of Natriuretic Peptides trials Research Report on Natriuretic Peptides
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study Study diet, Exercise capacity VO2 max determination, Exercise Challenge - Cardiovascular Diseases, Natriuretic Peptides | Not applicable | Recruiting | University of Alabama at Birmingham | 200 | 2022-04-01 | 2026-10-05 |
| PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis Sacubitril-Valsartan 49 Mg-51 Mg Oral Tablet, Valsartan 80 mg Oral Tablet - Obesity, Cardiovascular Diseases | Phase 2 / Phase 3 | Recruiting | University of Alabama at Birmingham | 160 | 2022-02-18 | 2026-04-09 |
| CARBON: UAB Cardiovascular Research Biobank Natriuretic Peptides, Cardiovascular Diseases | Recruiting | University of Alabama at Birmingham | 500 | 2022-01-01 | 2026-02-13 | |
| NAUTICAL: Effect of Natriuretic Peptide Augmentation on Cardiometabolic Health in Black Individuals Sacubitril, Valsartan 97-103 mg Oral Tablet, Valsartan 160 mg, Intravenous Glucose Tolerance Test - Diabetes Mellitus, Cardiovascular Diseases | Phase 2 | Recruiting | University of Alabama at Birmingham | 200 | 2020-08-15 | 2026-07-28 |
| The Diurnal Rhythm in Natriuretic Peptide Levels standardized Study Diet - Natriuretic Peptides, Obesity | Not applicable | Completed | University of Alabama at Birmingham | 42 | 2019-04-01 | 2024-02-05 |
| Racial Differences in the Natriuretic Peptide Response to Glucose Challenge Study diet, Glucose Challenge - Healthy, Natriuretic Peptides | Not applicable | Completed | University of Alabama at Birmingham | 81 | 2017-03-01 | 2023-06-22 |
| Electrolyte and Fluid Disturbances in Subarachnoid Hemorrhage and Traumatic Brain Injury Electrolyte Disturbances, Subarachnoid Hemorrhage | Completed | Insel Gruppe AG, University Hospital Bern | 85 | 2011-01-01 | 2013-04-17 |
Cardiovascular Diseases (4) · Obesity (4) · Diabetes Mellitus (2) · Hypertension (2) · Brain Injuries, Traumatic (1) · Diabetes Insipidus (1) · Inappropriate ADH Syndrome (1) · Insulin Resistance (1) · Metabolic Diseases (1) · Metabolic Syndrome (1) · Motor Activity (1) · Subarachnoid Hemorrhage (1)
Nutritional and Metabolic Diseases (7) · Pathological Conditions, Signs and Symptoms (5) · Body Weight (4) · Nutrition Disorders (4) · Overnutrition (4) · Overweight (4) · Signs and Symptoms (4) · Endocrine System Diseases (3) · Glucose Metabolism Disorders (3) · Metabolic Diseases (3) · Vascular Diseases (3) · Hyperinsulinism (2) · Behavior (1) · Brain Diseases (1) · Brain Injuries (1)
Tablets (2) · Valsartan (2) · Glucose Tolerance Test (1) · sacubitril (1) · sacubitril and valsartan sodium hydrate drug combination (1)
University of Alabama at Birmingham (6) · Insel Gruppe AG, University Hospital Bern (1)
United States (6) · Switzerland (1)
Pankaj Arora, MD, FAHA (4) · Pankaj Arora, MD (2) · Jan Wiegand, MD (1) · Jukka Takala, MD PhD (1) · Orlando M Gutierrez, MMSc (1) · Stephan Jakob, MD, PhD (1)
PMID 25595796, PMID 27542885, PMID 28330649, PMID 31162140, PMID 31588864, PMID 33958126
R01HL160982 (1), R01HL163081 (1), R01HL163852 (1)