16 completed, 4 unknown, 3 recruiting, 1 active not recruiting. 6 Phase 2, 6 Phase 3, 6 Phase 4, 5 Not applicable, 1 Early Phase 1.
Follow Nail Psoriasis: new trials by email Literature Review of Nail Psoriasis trials Research Report on Nail Psoriasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Open Label Trial to Evaluate Efficacy and Safety of Roflumilast 0.3% Cream for Chronic Plaque and Nail Psoriasis Roflumilast 0.3% topical cream - Chronic Plaque Psoriasis, Nail Psoriasis | Phase 4 | Recruiting | Modern Research Associates, PLLC | 15 | 2026-09-15 | 2026-10-01 |
| Topical Use of 2% Tofacitinib for Nail Psoriasis: an Exploratory Clinical Study Topical 2% Tofacitinib - Nail Psoriasis | Phase 2 | Active not recruiting | Hexsel Dermatology Clinic | 10 | 2026-09-01 | 2026-09-25 |
| Clinical Study on the Medical Device PROXERA PSOMED 30 for the Treatment of Nail Psoriasis: Evaluation of Safety and Efficacy Device intervention name: PROXERA PSOMED 30 nail cream; Control intervention name: Petrolatum - Nail Psoriasis | Not applicable | Recruiting | ICIM International S.r.l. | 21 | 2026-05-12 | 2026-07-28 |
| Study to Assess Efficacy, Safety and Tolerability of a Nail Patch in Patients With Nail Fragility, Mychosis, Psoriasis Cosmetic patch containing urea applicated daily for 3 months, Placebo patch application - Nail Psoriasis, Nail Damage | Phase 3 | Recruiting | Wooshin Labottach Co., Ltd. | 72 | 2026-02-01 | 2026-01-26 |
| Local Methotrexate Injections for the Treatment of Nail Psoriasis Methotrexate, Triamcinolone Acetonide 10mg/mL, Saline - Nail Psoriasis | Phase 4 | Terminated | Weill Medical College of Cornell University | 1 | 2025-09-10 | 2026-06-17 |
| Real-World Study of Xeligekimab for Moderate to Severe Plaque Psoriasis(XP-Real) Xeligekimab injection - Plaque Psoriasis, Psoriatic Arthritis | Not yet recruiting | Chongqing Genrix Biopharmaceutical Co., Ltd | 1000 | 2025-01-30 | 2025-01-31 | |
| An Investigator Initiated Open Label Study Evaluating the Efficacy and Tolerability of Oral Deucravacitinib for the Treatment of Nail Psoriasis Deucravacitinib - Nail Psoriasis | Early Phase 1 | Completed | University of Alabama at Birmingham | 1 | 2024-03-01 | 2026-01-08 |
| Methotrexate Alone vs Combination With Excimer Light in Nail Psoriasis Excimer laser, Methotrexate Injection - Nail Psoriasis | Not applicable | Unknown | Assiut University | 20 | 2023-12-01 | 2023-12-01 |
| Comparative Study of Intralesional Methotrexate Versus Intralesional Triamcinolone Acetonide in Treatment of Nail Psoriasis Methotrexate, Triamcinalone Acetonide - Nail Psoriasis | Phase 2 | Completed | Tanta University | 25 | 2023-05-01 | 2026-10-15 |
| Nd:YAG Laser and Radiofrequency in Treatment of Fingernail Psoriasis Radiofrequency - Nail Psoriasis | Not applicable | Unknown | Cairo University | 30 | 2023-01-20 | 2023-01-25 |
| Study of Efficacy and Safety of Investigational Treatment in Patients With Nail Psoriasis AT193 - Nail Psoriasis, Plaque Psoriasis | Phase 1 | Unknown | Azora Therapeutics Australia Pty Ltd | 34 | 2022-04-01 | 2023-01-25 |
| A Study Evaluating the Efficacy and Tolerability of Enstilar Foam in Patients With Nail Psoriasis Enstilar Foam - Nail Psoriasis | Phase 4 | Completed | University of Alabama at Birmingham | 6 | 2021-11-01 | 2025-01-17 |
| Assessing the Efficacy of Image-guided Laser-assisted Enstilar® Delivery for Treatment of Psoriatic Nails Enstilar, Ablative fractional laser - Nail Psoriasis | Phase 2 | Completed | Bispebjerg Hospital | 11 | 2020-10-02 | 2022-03-02 |
| Benefit of Placebo and Different Concentrations of Triamcinolone Acetonide in Nail Psoriasis Placebos, Triamcinolone Acetonide 2.5 mg/mL, Triamcinolone Acetonide 5.0 mg/mL - Nail Psoriasis, Nail Diseases | Phase 4 | Completed | Weill Medical College of Cornell University | 11 | 2020-03-11 | 2024-03-27 |
| Observational Study in Patients With Nail Psoriasis Treated With Enstilar® to Assess the Severity Change and the Quality of Life Calcipotriene and betamethasone dipropionate aerosol foam - Nail Psoriasis | Completed | Angeles Florez | 10 | 2019-03-26 | 2021-08-02 | |
| Quality of Life and Ultrasonographic Assessment of Nail Psoriasis After Treatment With Apremilast (JUST Study) Apremilast - Nail Psoriasis | Completed | Hospital de Granollers | 45 | 2018-02-23 | 2020-07-29 | |
| Methotrexate in the Treatment of Distal Interphalangeal Joint Extensor Tendon Enthesopathy in Nail Psoriasis Methotrexate - Nail Psoriasis | Completed | Ryszard Górecki | 32 | 2018-01-07 | 2018-11-28 | |
| Efficacy of Combined Fractional Carbon Dioxide Laser and Topical Tazarotene in the Treatment of Psoriatic Nail Disease fractional carbon dioxide laser, Tazarotene Cream 0.1% - Nail Psoriasis | Phase 4 | Unknown | Assiut University | 30 | 2017-10-01 | 2017-08-28 |
| Study to Evaluate the Efficacy and Safety of P-3073 Nail Solution in the Treatment of Mild to Moderate Psoriatic Fingernail/s P-3073 (calcipotriene 0.005%), Vehicle of P-3073 - Nail Psoriasis | Phase 3 | Withdrawn | Polichem S.A. | 2017-05-15 | 2018-01-10 | |
| Study to Evaluate the Efficacy and Safety of P-3073 Nail Solution in the Treatment of Nails Affected by Psoriasis P-3073, Vehicle of P-3073 - Nail Psoriasis | Phase 3 | Completed | Polichem S.A. | 378 | 2015-11-23 | 2018-03-08 |
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Psoriasis (5) · Nail Diseases (2) · Arthritis, Psoriatic (1) · Mycoses (1)
Skin Diseases (7) · Skin and Connective Tissue Diseases (7) · Skin Diseases, Papulosquamous (6) · Arthritis (1) · Bacterial Infections and Mycoses (1) · Bone Diseases (1) · Infections (1) · Joint Diseases (1) · Musculoskeletal Diseases (1) · Psoriasis (1) · Spinal Diseases (1) · Spondylarthritis (1) · Spondylarthropathies (1) · Spondylitis (1)
Methotrexate (4) · Lasers, Excimer (2) · Oils (2) · Triamcinolone Acetonide (2) · betamethasone dipropionate, calcipotriol drug combination (2) · calcipotriene (2) · Adalimumab (1) · Etanercept (1) · Injections (1) · Lasers, Dye (1) · Olive Oil (1) · Petrolatum (1) · Roflumilast (1) · Saline Solution (1) · Sodium Chloride (1)
Assiut University (2) · Polichem S.A. (2) · University of Alabama at Birmingham (2) · Weill Medical College of Cornell University (2) · AbbVie (1) · Almirall, S.A. (1) · Angeles Florez (1) · Azora Therapeutics Australia Pty Ltd (1) · Bispebjerg Hospital (1) · Cairo University (1) · Chang Gung Memorial Hospital (1) · Chongqing Genrix Biopharmaceutical Co., Ltd (1) · Hexsel Dermatology Clinic (1) · Hospital de Granollers (1) · ICIM International S.r.l. (1)
United States (7) · Egypt (2) · Germany (2) · Italy (2) · Poland (2) · Spain (2) · Australia (1) · Brazil (1) · Bulgaria (1) · China (1) · Czechia (1) · Denmark (1) · Greece (1) · Latvia (1) · Russia (1)
Maurizio Caserini, MD (2) · Shari Lipner, MD, PhD (2) · Boni E Elewski, Dr (1) · David Williams, MD (1) · Merete Haedersdal, MD PhD DMSc (1) · Sahar Abdel-Moez, MD (1) · Wang Gang, Prof (1) · Yin-Ku Lin, M.D., Ph.D. (1) · Yin-Ku Lin, MD. PhD. (1)
2015 (1), 2019 (1)