71 completed, 8 unknown, 4 not yet recruiting, 4 recruiting. 29 Phase 2, 24 Phase 1, 21 Phase 3, 12 Phase 4, 9 Not applicable.
Follow calcipotriene: new trials by email Literature Review of calcipotriene trials Research Report on calcipotriene
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Topical Calcipotriol and Intralesional Steroids in Alopecia Areata Calcipotriol, Triamcinolone Acetonide - Alopecia Areata | Phase 4 | Not yet recruiting | Hayat Abad Medical Complex, Peshawar | 60 | 2026-10-01 | 2026-09-21 |
| 5-Fluorouracil and Calcipotriene for Field Treatment of Actinic Keratoses Combination field therapy with 5-fluorouracil and calcipotriene (5FU/C) - Actinic Keratoses | Phase 1 | Not yet recruiting | Cedars-Sinai Medical Center | 96 | 2026-09-01 | 2026-10-05 |
| Utilization of a Microdevice for Psoriasis and Atopic Dermatitis In situ cutaneous microdevice, Triamcinolone, 5-Fluorouracil - Psoriasis, Atopic Dermatitis | Phase 4 | Not yet recruiting | University of California, San Francisco | 10 | 2026-08-01 | 2026-06-03 |
| Acupuncture With Chinese Herbal Cream Compare With Acupuncture With Calcipotriol in Plaque Psoriasis. Acupuncture, Calcipotriol 0.005% ointment, Chinese herb cream - Plaque Type Psorisis | Phase 2 | Recruiting | Mae Fah Luang University | 28 | 2026-02-09 | 2026-02-13 |
| A Pilot Clinical Trial Comparing Topical Fluorouracil to Fluorouracil Plus Calcipotriene Field Treatments in Patients With Multiple Actinic Keratoses Fluorouracil 5-FU, Fluorouracil/Calcipotriene - Multiple Actinic Keratoses | Phase 3 | Recruiting | M.D. Anderson Cancer Center | 30 | 2025-10-06 | 2026-10-02 |
| Topical Calcipotriol Versus Photodynamic Therapy in the Treatment of Oral Leukoplakia Calcipotriol 0.005% gel, ALA mediated PDT - Oral Leukoplakia | Phase 2 / Phase 3 | Active not recruiting | Alexandria University | 30 | 2025-07-16 | 2026-06-22 |
| COMPARISON OF EFFICACY AND SAFETY OF NARROWBAND UVB WITH 0.1% TACROLIMUS VS NARROWBAND UVB WITH 0.005% CALCIPOTRIOL IN TREATMENT OF VITILIGO Tacrolimus, Calcipotriol - Vitiligo - Macular Depigmentation, Tacrolimus | Early Phase 1 | Enrolling by invitation | Dr ayesha wahid | 60 | 2025-05-01 | 2025-06-24 |
| Efficacy of Topical 5-Fluorouracil Vs Calcipotriol As Photodynamic Therapy Pre-treatment for Field Actinic Keratoses 5-FU (fluorouracil), Calcipotriol - Actinic Keratosis of Face and Scalp, Actinic Keratoses | Not applicable | Not yet recruiting | St Vincent's University Hospital, Ireland | 50 | 2025-01-01 | 2024-11-12 |
| Testing the Efficacy of Topical Calcipotriene Plus 5-Fluorouracil Combination to Activate the Immune System Against Precancerous Skin Lesions in Organ Transplant Recipients Biopsy, Calcipotriene, Fluorouracil - Actinic Keratosis | Phase 2 | Active not recruiting | University of Arizona | 56 | 2024-07-02 | 2025-09-24 |
| Comparative Efficacy of Alpha Hydroxy Acids With and Without Nanocarriers Versus Calcipotriol Plus Betamethasone in Treatment of Plaque Psoriasis Alpha Hydroxy Acids with nanocarriers, Alpha Hydroxy Acids only., Calcipotriol plus betamethasone - Psoriasis | Not applicable | Completed | Al-Azhar University | 80 | 2024-03-15 | 2026-09-11 |
| Calcipotriol as a Novel Treatment for Central Centrifugal Cicatricial Alopecia (CCCA) Calcipotriol, Subject's already prescribed drug - Central Centrifugal Cicatricial Alopecia | Early Phase 1 | Withdrawn | Wake Forest University Health Sciences | 2023-08-01 | 2023-08-31 | |
| Evaluation of the Effect of Topical Calcipotriol Versus Platelet-Rich Plasma Calcipotriol - Alopecia Areata | Not applicable | Completed | Egymedicalpedia | 80 | 2023-07-01 | 2023-10-19 |
| Efficacy and Safety of Topical Vitamin D Analogue in Treatment of Female Pattern Hair Loss Topical minoxidil, Topical Vitamin D, Saline spray - Dermatology, Female Pattern Baldness | Phase 1 / Phase 2 | Unknown | Sohag University | 45 | 2023-05-20 | 2024-03-27 |
| Combination of Sotyktu and Enstilar for Plaque Psoriasis Enstilar, Deucravacitinib - Psoriasis | Phase 4 | Completed | Psoriasis Treatment Center of Central New Jersey | 30 | 2022-12-06 | 2024-03-25 |
| 5-Fluorouracil and Calcipotriene for Treatment of Low Grade Skin Cancer Combination cream of 5-fluorouracil and calcipotriene, 5-fluorouracil cream - Superficial Basal Cell Carcinoma, Squamous Cell Carcinoma in Situ | Phase 2 / Phase 3 | Recruiting | Boston University | 200 | 2022-10-15 | 2025-11-28 |
| A Phase III Study in Subjects With Mild to Moderate Psoriasis. AKP02/AKVANO cutaneous spray (calcipotriol 50 μg/g + betamethasone 0.5 mg/g/ AKVANO), Enstilar Topical Product (calcipotriol 50 μg/g + betamethasone 0.5 mg/g), Placebo - Mild to Moderate Psoriasis | Phase 3 | Unknown | Lipidor AB | 294 | 2022-01-24 | 2022-08-10 |
| Combination 5-FU / Calcipotriene Cream for SCCIS/SCC Combination topical 5-fluorouracil 5% / calcipotriene 0.005% cream, Nourivan Base Cream - Squamous Cell Carcinoma | Early Phase 1 | Unknown | Carilion Clinic | 30 | 2021-04-14 | 2023-02-13 |
| Efficacy and Safety of Sorilux in Maintenance Treatment of Moderate Type Plaque Psoriasis LEXETTE 0.05% Topical Foam, Sorilux 0.005 % Topical Foam, Vehicle Foam - Plaque Psoriasis | Phase 4 | Unknown | Skin Sciences, PLLC | 30 | 2021-01-01 | 2020-11-20 |
| Phototherapy Combination With Topicals in Vitiligo Tacrolimus 0.1% ointment twice daily plus NBUVB 3 times weekly, Calcipotriol/Betamethasone ointment plus NBUVB - Vitiligo, Generalized | Not applicable | Completed | Jordan University of Science and Technology | 41 | 2020-06-21 | 2026-10-27 |
| Efficacy and Safety of AD-MSCs Plus Calpocitriol Ointment and PSORI-CM01 Granule in Psoriasis Patients Calcipotriol ointment, PSORI-CM01 Granule, adipose-derived multipotent mesenchymal stem cells - Mesenchymal Stromal Cells, Psoriasis | Not applicable | Completed | Guangdong Provincial Hospital of Traditional Chinese Medicine | 8 | 2020-04-01 | 2023-08-24 |
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Psoriasis (27) · Keratosis, Actinic (6) · Alopecia Areata (3) · Alopecia (2) · Carcinoma, Squamous Cell (2) · Dermatitis, Atopic (2) · Plaque, Amyloid (2) · Pruritus (2) · Vitiligo (2) · Acne Vulgaris (1) · Arthritis (1) · Breast Neoplasms (1) · Carcinoma (1) · Dermatitis, Allergic Contact (1) · Diffuse alopecia (1)
LEO Pharma (27) · Haus Bioceuticals (2) · Mayne Pharma International Pty Ltd (2) · Pfizer (2) · Abbott (1) · Al-Azhar University (1) · Alexandria University (1) · Angeles Florez (1) · Aswan University Hospital (1) · Bayer (1) · Boston University (1) · Cadila Pharnmaceuticals (1) · Carilion Clinic (1) · Cedars-Sinai Medical Center (1) · Children's Hospital Medical Center, Cincinnati (1)
United States (35) · Germany (18) · Canada (14) · France (13) · United Kingdom (11) · Denmark (5) · Egypt (5) · Sweden (5) · Belgium (4) · Spain (4) · Finland (3) · Netherlands (3) · China (2) · India (2) · South Korea (2)
Catherine Queille-Roussel, MD (3) · Colin Fleming, MD (2) · Adele R Clark, PA-C (1) · Alan B Fleischer, Jr, M.D. (1) · Alan Menter, MD (1) · Alexandra B Kimball, MD (1) · Alicia Bucko, MD (1) · Amy M Morris, MD (1) · Amy McMichael, MD (1) · Amy S Paller, MD (1) · Andrew King, MD (1) · Anil Avhad, MBBS (1)
PMID 15099362, PMID 15214905, PMID 17135738, PMID 17310004, PMID 17314973, PMID 19067709, PMID 20513160, PMID 20713833, PMID 21293107, PMID 23097521, PMID 23178916, PMID 25738921, PMID 27869649, PMID 28635045, PMID 29241771, PMID 29502110, PMID 31360041, PMID 32342443, PMID 32767679, PMID 32785881, PMID 34397196, PMID 37644869
2009 (1), 2014 (1), 2017 (1), P30CA023074 (1), P50CA121973 (1), R01AR053542 (1), UG1CA242596 (1)