5 completed, 3 recruiting, 2 not yet recruiting, 2 unknown. 13 Phase 2, 3 Phase 1, 3 Phase 3.
Follow Myeloid Leukemia: new trials by email Literature Review of Myeloid Leukemia trials Research Report on Myeloid Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 1/2 FLAG-IDA, VEN and Asciminib in CML and Ph+ AML Fludarabine, Cytarabine, Idarubicin - Myeloid Leukemia | Phase 1 / Phase 2 | Not yet recruiting | M.D. Anderson Cancer Center | 30 | 2026-11-30 | 2026-10-13 |
| Radioimmunotherapy Conditioning With 131I- Apamistamab for Allogeneic Transplant in Relapse/Refractory AML 131I-apamistamab, Fludarabine, Cyclophosphamide - Acute Leukemia, Myeloid Leukemia | Phase 2 / Phase 3 | Not yet recruiting | Actinium Pharmaceuticals | 306 | 2026-01-01 | 2025-09-10 |
| A Phase I/II Study of Gilteritinib and Momelotinib for Patients With Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia Gilteritinib, Momelotinib - Myeloid Leukemia | Phase 1 / Phase 2 | Recruiting | M.D. Anderson Cancer Center | 40 | 2024-05-22 | 2026-10-05 |
| Interferon-α for TP53 Myeloid Malignancy Post Allo-HSCT IFN-Α - Myeloid Leukemia, Myelodysplastic Syndromes | Phase 2 | Recruiting | Peking University People's Hospital | 35 | 2024-01-01 | 2025-06-03 |
| Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors Nicotinamide Riboside, Placebo, Exercise Intervention - Lymphoblastic Leukemia, Cancer Survivors | Phase 2 | Recruiting | Children's Hospital of Philadelphia | 80 | 2023-02-23 | 2025-12-04 |
| Therapeutic Use of Intravenous Vitamin C in Allogeneic Stem Cell Transplant Recipients Intravenous (IV) and oral Vitamin C - Lymphoid Leukemia, Myeloid Leukemia | Phase 2 | Completed | Virginia Commonwealth University | 61 | 2018-10-01 | 2023-11-07 |
| Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies CAR-T cell immunotherapy - B-cell Acute Lymphoblastic Leukemia, Lymphoma | Phase 1 / Phase 2 | Unknown | Shenzhen BinDeBio Ltd. | 73 | 2018-03-01 | 2019-12-11 |
| NK Cells as Consolidation Therapy of Acute Myeloid Leukemia in Children/Adolescents cyclophosphamide, Fludarabine, NK cell infusion - Acute Myeloid Leukemia, Leukemia | Phase 2 | Completed | Instituto de Investigación Hospital Universitario La Paz | 7 | 2016-05-01 | 2020-10-05 |
| Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in With High-Risk Hematologic Malignancies Fludarabine phosphate, Busulfan, Total-Body Irradiation - Acute Myeloid Leukemia With FLT3/ITD Mutation, Acute Myeloid Leukemia With Gene Mutations | Phase 2 | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 62 | 2012-12-24 | 2025-10-30 |
| Efficacy and Safety of a Donor Lymphocyte Preparation Depleted of Functional Host Alloreactive T-cells (ATIR) in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical Donor Donor lymphocyte preparation depleted of host functional alloreactive T-cells - Myeloid Leukemia, Lymphoblastic Leukemia | Phase 2 / Phase 3 | Terminated | Kiadis Pharma | 40 | 2009-08-01 | 2021-06-14 |
| Therapy-Optimization Trial for the Treatment of Acute Myeloid Leukemias (AML) in Children and Adolescents Anthracyclines, liposomal daunorubicin, 2-CDA - Myeloid Leukemia | Phase 2 / Phase 3 | Unknown | University Hospital Muenster | 550 | 2004-03-01 | 2012-05-23 |
| Trial Comparing Pegfilgrastim With Filgrastim as an Adjunct to Chemotherapy for Acute Myeloid Leukaemia (AML) filgrastim, pegfilgrastim - Myeloid Leukemia | Phase 2 | Completed | Amgen | 84 | 2003-03-01 | 2008-10-31 |
| Immunosuppressive Preparation Followed by Blood Cell Transplant for the Treatment of Blood Cancers in Older Adults Blood cell transplantation - Chronic Lymphocytic Leukemia, Graft vs Host Disease | Phase 2 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 28 | 1997-09-29 | 2019-12-17 |
Leukemia, Myeloid (13) · Leukemia, Myeloid, Acute (6) · Myelodysplastic Syndromes (5) · Leukemia (4) · Graft vs Host Disease (3) · Multiple Myeloma (3) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (3) · Anemia, Aplastic (2) · Leukemia, Lymphocytic, Chronic, B-Cell (2) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (2) · Lymphoma (2) · Anemia, Refractory, with Excess of Blasts (1) · Burkitt Lymphoma (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Renal Cell (1)
Hematologic Diseases (13) · Hemic and Lymphatic Diseases (13) · Neoplasms (13) · Neoplasms by Histologic Type (13) · Leukemia (9) · Bone Marrow Diseases (6) · Immune System Diseases (6) · Immunoproliferative Disorders (6) · Lymphatic Diseases (6) · Lymphoproliferative Disorders (6) · Leukemia, Lymphoid (4) · Anemia (3) · Blood Protein Disorders (3) · Cardiovascular Diseases (3) · Hemorrhagic Disorders (3)
Cyclophosphamide (3) · fludarabine (3) · Filgrastim (2) · Idarubicin (2) · Whole-Body Irradiation (2) · fludarabine phosphate (2) · Anthracyclines (1) · Ascorbic Acid (1) · Busulfan (1) · Cladribine (1) · Cytarabine (1) · Daunorubicin (1) · Immunotherapy, Adoptive (1) · Interleukin-2 (1) · Mycophenolic Acid (1)
M.D. Anderson Cancer Center (2) · Actinium Pharmaceuticals (1) · Amgen (1) · Children's Hospital of Philadelphia (1) · Instituto de Investigación Hospital Universitario La Paz (1) · Kiadis Pharma (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · Peking University People's Hospital (1) · Shenzhen BinDeBio Ltd. (1) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (1) · University Hospital Muenster (1) · Virginia Commonwealth University (1)
United States (7) · China (2) · Germany (2) · Belgium (1) · Canada (1) · Italy (1) · Netherlands (1) · Spain (1) · United Kingdom (1)
A. John Barrett, M.D. (1) · Andrea Velardi, MD (1) · Denis-Claude Roy, MD (1) · Dirk Reinhardt, Prof. Dr. med. (1) · Dolores Grosso, RN, CRNP, DNP (1) · Fadi Haddad, MD (1) · Katy Rezvani, MD PhD (1) · Neal Flomenberg, MD (1) · Nicholas Short, MD (1) · Sogol Mostoufi-Moab, MD, MSCE (1) · Stephan Mielke, MD (1) · Ursula Creutzig, Prof. Dr. med. (1) · William B Clark, MD (1)
PMID 18083847, PMID 18182574, PMID 18616811, PMID 21480469, PMID 23704089, PMID 26814618, PMID 27269945, PMID 31919123, PMID 33610500, PMID 35854224, PMID 40803346
2015 (1), R01CA254955 (1)