Multiple Myeloma: Clinical Trials

22 trials for Multiple Myeloma, newest first

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22 completed. 22 Phase 4.

By phase and status

PhaseTrialsStatus
Phase 422Completed 22

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Trials (filtered) newest first · largest first

All 22 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Alternative Dosing Scheme of Pomalidomide 4 mg Every Other Day Versus Pomalidomide 2 mg and 4 mg Every Day; the POMAlternative Study
Pomalidomide 4 mg every day in cycle 1, Pomalidomide 4 mg every other day in cycle 2, Pomalidomide 2 mg every day in cycle 2 - Multiple Myeloma in Relapse, Multiple Myeloma
Phase 4CompletedAmsterdam UMC, location VUmc122022-12-012025-04-22
Home Based Daratumumab Administration for Patients With Multiple Myeloma
Daratumumab and Hyaluronidase-fihj, Questionnaire Administration, Quality-of-Life Assessment - Plasma Cell Myeloma
Phase 4CompletedThomas Jefferson University202022-11-082025-11-21
Evaluate Safety and Efficacy of High-dose Melphalan HCL for Injection in MM Patients With Auto-HSC Transplantation
Melphalan Hydrochloride for Injection - Multiple Myeloma
Phase 4CompletedCASI Pharmaceuticals (China) Co., Ltd.672020-07-242024-05-23
Ixazomib, Lenalidomide, and Combination for Maintenance in NDMM Patients
Ixazomib, Lenalidomide - Multiple Myeloma
Phase 4CompletedPeking Union Medical College Hospital2112019-09-242024-08-01
Study to Evaluate Safety Tolerability & Efficacy of Kyprolis (Carfilzomib) in Relapsed or Refractory Multiple Myeloma
Drug: Carfilzomib + Dexamethasone, Drug: Carfilzomib + Lenalidomide + Dexamethasone - Relapsed Refractory Multiple Myeloma
Phase 4CompletedAmgen1012019-09-162026-05-11
A Study of DARZALEX (Daratumumab) In Indian Participants With Relapsed and Refractory Multiple Myeloma, Whose Prior Therapy Included a Proteasome Inhibitor and an Immunomodulatory Agent
Daratumumab - Multiple Myeloma
Phase 4CompletedJohnson & Johnson Private Limited1502019-06-102025-02-03
Pneumococcal Vaccination of Multiple Myeloma Patients on Novel Agents
Vaccination with pneumococcal conjugate vaccine (PCV13), Standard Antibacterial Prophylaxis - Multiple Myeloma, Pneumococcal Infection
Phase 4CompletedMinsk Scientific-Practical Center for Surgery, Transplantation and Hematology362018-07-012022-08-31
Apixaban for Primary Prevention of Venous Thromboembolism in Patients With Multiple Myeloma
Apixaban - Venous Thromboembolism, Multiple Myeloma
Phase 4CompletedGregory Piazza502018-02-282019-12-17
Prolonged Protection From Bone Disease in Multiple Myeloma
Zoledronic acid - Multiple Myeloma
Phase 4CompletedThomas Lund1582015-01-012023-02-17
A Pharmacokinetic Study of Bortezomib in Taiwanese Participants With Multiple Myeloma
Bortezomib - Multiple Myeloma
Phase 4CompletedJohnson & Johnson Taiwan Ltd182014-12-012016-07-11
Lenalidomide and Dexamethasone With/Without Stem Cell Transplant in Patients With Multiple Myeloma
Autologous peripheral blood stem cell transplant, Lenalidomide, Dexamethasone - Multiple Myeloma
Phase 4CompletedColumbia University602012-09-012020-02-05
Zoledronic Acid in Patients With Multiple Myeloma and Asymptomatic Biochemical Relapse
zoledronic acid, No treatment control - Multiple Myeloma
Phase 4CompletedPETHEMA Foundation1032010-04-012020-04-06
Zoledronic Acid Treatment (Every 4 or 12 Weeks) to Prevent Skeletal Complications in Advanced Multiple Myeloma Participants
zoledronic acid - Multiple Myeloma
Phase 4CompletedNovartis Pharmaceuticals1212007-11-072021-05-26
Bortezomib/Adriamycine/Melfalan/Prednisone (VAMP)/Thalidomide/Cyclophosphamide/Dexamethasone (TaCyDex) or Bortezomib/Melfalan/Prednisone (V-MP)/TaCyDex) in Refractary or Relapsed Multiple Myeloma
Bortezomib, Thalidomide - Multiple Myeloma
Phase 4CompletedPETHEMA Foundation402007-01-012011-09-19
Long Term Efficacy and Safety of Zoledronic Acid Treatment in Patients With Bone Metastases
Zoledronic acid - Bone Neoplasms
Phase 4CompletedNovartis Pharmaceuticals732006-12-012017-02-27
PROMPT - Palifermin in Reduction of Oral Mucositis in PBSC Transplantation
Kepivance (Palifermin) - Non-Hodgkin's Lymphoma, Multiple Myeloma
Phase 4CompletedSwedish Orphan Biovitrum1452006-04-012014-11-03
Stage I Multiple Myeloma Treatment
zometa - Multiple Myeloma
Phase 4CompletedCentre Hospitalier Universitaire de Nice892004-12-012024-04-12
A Multiple Myeloma Trial in Patients With Bone Metastases
zoledronic acid - Multiple Myeloma
Phase 4CompletedNovartis Pharmaceuticals1792004-10-012011-06-29
FREE Study - Fracture Reduction Evaluation
Balloon Kyphoplasty - Osteopenia, Osteoporosis
Phase 4CompletedMedtronic Spine LLC3002003-02-012017-12-08
Treatment With Zoledronic Acid in Patients With Breast Cancer, Multiple Myeloma, and Prostate Cancer With Cancer Related Bone Lesions
zoledronic acid - Breast Cancer, Multiple Myeloma
Phase 4CompletedNovartis5002001-10-012012-02-01

Showing 20 of 22. Sign in to see all of them.

Narrower conditions

Bone Neoplasms (2)  ·  Breast Neoplasms (2)  ·  Lymphoma, Non-Hodgkin (2)  ·  Prostatic Neoplasms (2)  ·  Recurrence (2)  ·  Anemia (1)  ·  Back Pain (1)  ·  Blast Crisis (1)  ·  Bone Diseases, Metabolic (1)  ·  Burkitt Lymphoma (1)  ·  Dendritic Cell Sarcoma, Interdigitating (1)  ·  Febrile Neutropenia (1)  ·  Graft vs Host Disease (1)  ·  Hodgkin Disease (1)

Broader conditions

Blood Protein Disorders (22)  ·  Cardiovascular Diseases (22)  ·  Hematologic Diseases (22)  ·  Hemic and Lymphatic Diseases (22)  ·  Hemorrhagic Disorders (22)  ·  Hemostatic Disorders (22)  ·  Immune System Diseases (22)  ·  Immunoproliferative Disorders (22)  ·  Lymphoproliferative Disorders (22)  ·  Neoplasms (22)  ·  Neoplasms by Histologic Type (22)  ·  Paraproteinemias (22)  ·  Vascular Diseases (22)  ·  Neoplasms, Plasma Cell (21)  ·  Pathological Conditions, Signs and Symptoms (5)

Interventions

Zoledronic Acid (7)  ·  Bortezomib (3)  ·  Lenalidomide (3)  ·  Cyclophosphamide (2)  ·  Dexamethasone (2)  ·  Filgrastim (2)  ·  Melphalan (2)  ·  daratumumab (2)  ·  Antilymphocyte Serum (1)  ·  Calcium Dobesilate (1)  ·  Fibroblast Growth Factor 7 (1)  ·  Granulocyte Colony-Stimulating Factor (1)  ·  Hematopoietic Stem Cell Mobilization (1)  ·  Injections (1)  ·  Interviews as Topic (1)

Sponsors

Novartis Pharmaceuticals (3)  ·  PETHEMA Foundation (2)  ·  Amgen (1)  ·  Amsterdam UMC, location VUmc (1)  ·  CASI Pharmaceuticals (China) Co., Ltd. (1)  ·  Centre Hospitalier Universitaire de Nice (1)  ·  Columbia University (1)  ·  Gregory Piazza (1)  ·  Johnson & Johnson Private Limited (1)  ·  Johnson & Johnson Taiwan Ltd (1)  ·  Medtronic Spine LLC (1)  ·  Millennium Pharmaceuticals, Inc. (1)  ·  Minsk Scientific-Practical Center for Surgery, Transplantation and Hematology (1)  ·  Novartis (1)  ·  Peking Union Medical College Hospital (1)

Countries

United States (9)  ·  China (2)  ·  India (2)  ·  Spain (2)  ·  Australia (1)  ·  Belarus (1)  ·  Denmark (1)  ·  France (1)  ·  Netherlands (1)  ·  Taiwan (1)

Top investigators

Adam R Binder, MD (1)  ·  Anatoly Uss, MD/PhD (1)  ·  Barry R. Meisenberg, MD (1)  ·  Ian Walters, M.D. (1)  ·  Junling Zhuang, MD (1)  ·  Kaiyan Liu (1)  ·  Sonja Zweegman, MD PhD (1)  ·  Suzanne Lentzsch, MD (1)  ·  Thomas LunD, MD Ph.D. (1)

Results publications

PMID 19246088, PMID 21912321, PMID 22443312, PMID 23446769, PMID 26069291, PMID 26644410, PMID 32418789, PMID 34582035, PMID 38116642, PMID 40396505

NIH funding

2014 (1)