4 recruiting, 1 suspended, 1 terminated. 3 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Recruiting 2, Suspended 1 |
| Phase 2 | 1 | Terminated 1 |
Follow MSH2 Gene Mutation: new trials by email Literature Review of MSH2 Gene Mutation trials Research Report on MSH2 Gene Mutation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Liquid Biopsy and Machine Learning for Early Colorectal Cancer, Adenomas, Lynch Cancers, and Residual Disease Detection BEACON - Colorectal Cancer, Adenoma Colon | Recruiting | San Raffaele University | 1200 | 2024-01-01 | 2026-03-04 | |
| Lynch Syndrome X-Talk of Enteral Mucosa With Immune System LYNX EYE (Lynch syndrome X-Talk of Enteral mucosa with Immune System) - Lynch Syndrome, Lynch Syndrome I | Recruiting | San Raffaele University | 300 | 2023-06-01 | 2026-04-24 | |
| An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results Intervention Arm At-risk Relative/ARR Contacts, MyGene Portal, Standard of Care - BRCA1 Mutation, POLD1 Gene Mutation | Not applicable | Recruiting | Memorial Sloan Kettering Cancer Center | 1000 | 2022-12-01 | 2026-08-27 |
| Videocapsule Endoscopy in Lynch Syndrome Video capsule endoscopy - Lynch Syndrome, Lynch Syndrome I | Not applicable | Recruiting | San Raffaele University | 100 | 2018-11-01 | 2026-04-22 |
| Nivolumab in Preventing Colon Adenomas in Participants With Lynch Syndrome and a History of Partial Colectomy Nivolumab - Colon Adenoma, Colon Carcinoma | Phase 2 | Terminated | John Hays | 3 | 2018-10-04 | 2024-07-01 |
| Stand up to Cancer: MAGENTA (Making Genetic Testing Accessible) Educational Intervention, Genetic Counseling, Laboratory Biomarker Analysis - BARD1 Gene Mutation, BRCA1 Gene Mutation | Not applicable | Suspended | M.D. Anderson Cancer Center | 5200 | 2017-04-18 | 2026-08-26 |
Colorectal Neoplasms, Hereditary Nonpolyposis (4) · Lynch Syndrome II (3) · Colonic Neoplasms (2) · Colorectal Neoplasms (2) · Lynch syndrome I (site-specific colonic cancer) (2) · Turcot syndrome (2) · Colonic Diseases (1) · Endometrial Neoplasms (1) · Neoplastic Syndromes, Hereditary (1) · Triple Negative Breast Neoplasms (1)
Neoplasms (5) · Neoplasms by Site (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · DNA Repair-Deficiency Disorders (4) · Digestive System Diseases (4) · Digestive System Neoplasms (4) · Gastrointestinal Diseases (4) · Gastrointestinal Neoplasms (4) · Genetic Diseases, Inborn (4) · Intestinal Diseases (4) · Intestinal Neoplasms (4) · Metabolic Diseases (4) · Nutritional and Metabolic Diseases (4) · Colonic Diseases (3) · Neoplastic Syndromes, Hereditary (3)
Capsule Endoscopy (1) · Early Intervention, Educational (1) · Educational Status (1) · Genetic Counseling (1) · Methods (1) · Nivolumab (1) · Standard of Care (1)
San Raffaele University (3) · John Hays (1) · M.D. Anderson Cancer Center (1) · Memorial Sloan Kettering Cancer Center (1)
United States (4) · Italy (3)
Giulia Martina Cavestro, MD, PhD (2) · John Hays, MD, Ph.D (1) · Kenneth Offit, MD, MPH (1) · Roni Wilke (1)