1 completed, 1 enrolling by invitation, 1 recruiting, 1 unknown. 4 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 1, Enrolling by invitation 1, Recruiting 1, Unknown 1 |
| Phase 1 | 1 | Recruiting 1 |
Follow Monotherapy: new trials by email Literature Review of Monotherapy trials Research Report on Monotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Study on the Early Bactericidal Activity of Contezolid Against Mycobacterium Abscessus Disease Contezolid, linezolid - Monotherapy, Mycobacterium Abscessus Infection | Phase 2 | Enrolling by invitation | Beijing Chest Hospital | 24 | 2026-01-01 | 2026-01-28 |
| Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF). Mirdametinib - NF1, Cutaneous Neurofibroma | Phase 1 / Phase 2 | Recruiting | Johns Hopkins University | 24 | 2024-02-12 | 2026-04-13 |
| Early Simplified: A Trial to Compare the Efficacy of Standard of Care Combination Antiretroviral Therapy With a Simplified Dolutegravir Monotherapy in Patients With a Primary HIV-1 Infection Dolutegravir, Standard of care combinational antiretroviral therapy - Monotherapy, Dolutegravir | Phase 2 | Unknown | University of Zurich | 101 | 2016-11-01 | 2018-10-12 |
| A Pilot Study of MONOtherapy of DOlutegravir in HIV-1 Virologically Suppressed Patients Dolutegravir - Human Immunodeficiency Virus, Dolutegravir | Phase 2 | Completed | Calmy Alexandra | 8 | 2016-06-01 | 2017-11-01 |
Acquired Immunodeficiency Syndrome (1) · HIV Infections (1) · Mycobacterium Infections, Nontuberculous (1)
Infections (2) · Actinomycetales Infections (1) · Bacterial Infections (1) · Bacterial Infections and Mycoses (1) · Blood-Borne Infections (1) · Communicable Diseases (1) · Genital Diseases (1) · Gram-Positive Bacterial Infections (1) · Immune System Diseases (1) · Immunologic Deficiency Syndromes (1) · Lentivirus Infections (1) · Mycobacterium Infections (1) · RNA Virus Infections (1) · Retroviridae Infections (1) · Sexually Transmitted Diseases (1)
dolutegravir (2) · Linezolid (1) · Oxazolidinones (1) · contezolid (1) · mirdametinib (1)
Beijing Chest Hospital (1) · Calmy Alexandra (1) · Johns Hopkins University (1) · University of Zurich (1)
Switzerland (2) · China (1) · United States (1)
Carlos Romo, MD (1) · Delphine Sculier, MD (1) · Dominique L Braun, MD (1) · Wenjuan Nie, Director (1)