2 active not recruiting, 2 completed, 1 not yet recruiting. 4 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Active not recruiting 2, Completed 1, Not yet recruiting 1 |
| Phase 1 | 1 | Completed 1 |
Follow Metastatic Gastrointestinal Stromal Tumor: new trials by email Literature Review of Metastatic Gastrointestinal Stromal Tumor trials Research Report on Metastatic Gastrointestinal Stromal Tumor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Autologous Tumor Infiltrating Lymphocytes With Interleukin-2 for the Treatment of Locally Advanced, Recurrent or Metastatic Gastrointestinal Stromal Tumors Aldesleukin, Biospecimen Collection, Chest Radiography - Locally Advanced Gastrointestinal Stromal Tumor, Metastatic Gastrointestinal Stromal Tumor | Phase 2 | Not yet recruiting | Joal Beane | 59 | 2027-02-15 | 2026-10-13 |
| A Prospective, Randomized, Multicenter, Comparative Study of the Efficacy of Imatinib Resumption Combined With Atezolizumab Versus Imatinib Resumption Alone in Patients With Unresectable Advanced Gastrointestinal Stromal Tumors (GIST) After Failure of Standard Treatments Atezolizumab 1200 mg, Imatinib 400 MG - Unresectable Gastrointestinal Stromal Tumor (GIST), Locally Advanced Gastrointestinal Stromal Tumor (GIST) | Phase 2 | Active not recruiting | Centre Leon Berard | 58 | 2022-01-14 | 2026-10-22 |
| Testing the Anti-cancer Drug, Rogaratinib (BAY 1163877), for Treatment of Advanced Sarcoma With Alteration in Fibroblast Growth Factor Receptor (FGFR 1-4), and in Patients With SDH-deficient Gastrointestinal Stromal Tumor (GIST) Biopsy Procedure, Biospecimen Collection, Computed Tomography - Locally Advanced Gastrointestinal Stromal Tumor, Locally Advanced Sarcoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 48 | 2021-05-03 | 2026-07-31 |
| Ph II CABOGIST in GIST cabozantinib - Metastatic Gastrointestinal Stromal Tumor | Phase 2 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 51 | 2017-02-02 | 2021-07-15 |
| Ipilimumab and Imatinib Mesylate in Advanced Cancer Imatinib Mesylate, Ipilimumab - Advanced Malignant Solid Neoplasm, C-KIT Tyrosine Kinase Protein Overexpression | Phase 1 | Completed | M.D. Anderson Cancer Center | 68 | 2013-02-19 | 2024-03-21 |
Gastrointestinal Stromal Tumors (5) · Melanoma (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Sarcoma (1)
Digestive System Diseases (5) · Digestive System Neoplasms (5) · Gastrointestinal Diseases (5) · Gastrointestinal Neoplasms (5) · Neoplasms by Histologic Type (5) · Neoplasms, Connective Tissue (5) · Neoplasms, Connective and Soft Tissue (5) · Neoplasms (4) · Neoplasms by Site (1) · Neoplasms, Germ Cell and Embryonal (1) · Neoplasms, Nerve Tissue (1) · Neoplastic Processes (1) · Neuroectodermal Tumors (1) · Neuroendocrine Tumors (1) · Nevi and Melanomas (1)
Imatinib Mesylate (2) · Magnetic Resonance Spectroscopy (2) · Specimen Handling (2) · Biopsy (1) · CTLA-4 Antigen (1) · Cyclophosphamide (1) · Filgrastim (1) · Granulocyte Colony-Stimulating Factor (1) · Ipilimumab (1) · Rogaratinib (1) · Surgical Procedures, Operative (1) · X-Rays (1) · aldesleukin (1) · atezolizumab (1) · cabozantinib (1)
Centre Leon Berard (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · Joal Beane (1) · M.D. Anderson Cancer Center (1) · National Cancer Institute (NCI) (1)
United States (3) · France (2) · Belgium (1) · Czechia (1) · Germany (1) · Hungary (1) · United Kingdom (1)
David S Hong (1) · Joal Beane, MD (1) · Suzanne George (1)
PMID 28428884, PMID 32470848, PMID 35481400, PMID 38573872, PMID 42191879
2014 (1), P30CA016672 (1), UM1CA186709 (1)