4 recruiting, 3 unknown, 1 active not recruiting. 8 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Recruiting 4, Unknown 3, Active not recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Metastatic Esophageal Squamous Cell Carcinoma: new trials by email Literature Review of Metastatic Esophageal Squamous Cell Carcinoma trials Research Report on Metastatic Esophageal Squamous Cell Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study Investigating Alternate Schedules of Tislelizumab Plus Chemotherapy in Japanese Patients With First-line Advanced ESCC Tislelizumab, Oxaliplatin, Leucovorin - Advanced Esophageal Squamous Cell Carcinoma, Metastatic Esophageal Squamous Cell Carcinoma | Phase 2 | Recruiting | BeOne Medicines | 30 | 2026-09-14 | 2026-10-26 |
| Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program Home Health Encounter, Nivolumab, Patient Monitoring - Advanced Esophageal Squamous Cell Carcinoma, Advanced Renal Cell Carcinoma | Phase 2 | Recruiting | Mayo Clinic | 50 | 2024-04-30 | 2026-10-02 |
| Sintilimab and Chemotherapy Sequential Radiotherapy in Advanced Esophageal Cancer TP regimen (cis-platinum ; Tocetaxel ) combined with PD-1 inhibitors（Sintilimab） - Metastatic Esophageal Squamous Cell Carcinoma | Phase 2 / Phase 3 | Recruiting | Qingdao Central Hospital | 90 | 2023-09-20 | 2024-07-24 |
| Radiotherapy Combined With Immunochemotherapy in Metastatic Esophageal Squamous Cell Carcinoma LDRT+CFRT, Immunotherapy, Chemotherapy - Esophageal Squamous Cell Carcinoma, Esophageal Cancer | Phase 2 | Recruiting | Shanghai Chest Hospital | 100 | 2023-01-01 | 2026-01-22 |
| AK104 Alone or in Combination With Chemotherapy in the First-line Treatment of ESCC AK104, Cisplatin, Paclitaxel - Unresectable Esophageal Squamous Cell Carcinoma, Locally Advanced Esophageal Squamous Cell Carcinoma | Phase 2 | Unknown | Chinese Academy of Medical Sciences | 80 | 2022-10-01 | 2022-08-31 |
| Concurrent Chemoradiotherapy for Stage IVB Esophageal Squamous Cell Carcinoma（EC-CRT-003） Intensity-modulated radiotherapy concurrent with capecitabine - Metastatic Esophageal Squamous Cell Carcinoma | Phase 2 | Unknown | Sun Yat-sen University | 126 | 2022-09-20 | 2023-11-18 |
| The Ave-CRT Study for Newly Diagnosed Metastatic Esophageal Squamous Cell Carcinoma Avelumab - Esophageal Tumor, Metastatic Esophageal Squamous Cell Carcinoma | Phase 2 | Unknown | National Taiwan University Hospital | 26 | 2019-03-20 | 2021-09-08 |
| Paclitaxel With or Without Cixutumumab as Second-Line Therapy in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer Cixutumumab, Laboratory Biomarker Analysis, Paclitaxel - Metastatic Esophageal Adenocarcinoma, Metastatic Esophageal Squamous Cell Carcinoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 94 | 2010-09-21 | 2026-09-10 |
Esophageal Squamous Cell Carcinoma (8) · Esophageal Neoplasms (4) · Adenocarcinoma Of Esophagus (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Renal Cell (1) · Carcinoma, Transitional Cell (1) · Colorectal Neoplasms (1) · Melanoma (1) · Squamous Cell Carcinoma of Head and Neck (1)
Carcinoma (8) · Carcinoma, Squamous Cell (8) · Digestive System Diseases (8) · Digestive System Neoplasms (8) · Esophageal Diseases (8) · Gastrointestinal Diseases (8) · Gastrointestinal Neoplasms (8) · Head and Neck Neoplasms (8) · Neoplasms (8) · Neoplasms by Histologic Type (8) · Neoplasms by Site (8) · Neoplasms, Glandular and Epithelial (8) · Neoplasms, Squamous Cell (8) · Esophageal Neoplasms (4) · Adenocarcinoma (1)
Cisplatin (2) · Paclitaxel (2) · Capecitabine (1) · Drug Therapy (1) · Fluorouracil (1) · Home Care Services (1) · House Calls (1) · Immunotherapy (1) · Leucovorin (1) · Nivolumab (1) · Oxaliplatin (1) · Remote Patient Monitoring (1) · TP protocol (1) · Taxes (1) · avelumab (1)
BeOne Medicines (1) · Chinese Academy of Medical Sciences (1) · Mayo Clinic (1) · National Cancer Institute (NCI) (1) · National Taiwan University Hospital (1) · Qingdao Central Hospital (1) · Shanghai Chest Hospital (1) · Sun Yat-sen University (1)
China (3) · United States (2) · Japan (1) · Taiwan (1)
Chia-Hsien Cheng (1) · Jing Huang, M.D. (1) · Roxana S. Dronca, M.D. (1) · Steven J Cohen (1) · Wen Yu, M.D (1)
PMID 37104870, PMID 37937444, PMID 41167638
U10CA021115 (1), U10CA180820 (1)