13 completed, 13 unknown, 7 recruiting, 4 not yet recruiting. 42 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 42 | Completed 13, Unknown 13, Recruiting 7, Not yet recruiting 4, Active not recruiting 2, Terminated 2, Suspended 1 |
Follow Margins of Excision: new trials by email Literature Review of Margins of Excision trials Research Report on Margins of Excision
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PIRe 2.0: A Stepped-Care Model for Involving Relatives Across Sectors Supportive Care - Brain Injuries, Acute, Brain Tumor Adult | Not applicable | Not yet recruiting | Copenhagen University Hospital, Rigshospitalet | 160 | 2026-10-01 | 2026-05-19 |
| Ultrasound-Guided Versus Standard Margin Selection in Ileocecal Resection of Terminal Ileal CD IOUS-guided margin selection - Crohn's Disease (CD) | Not applicable | Recruiting | The Cleveland Clinic | 22 | 2026-09-01 | 2026-08-27 |
| HISMAR: Intraoperative Margin Assessment Using the Histolog® Scanner to Reduce Reoperation in Breast-Conserving Surgery Histolog® Scanner - Breast Cancer, Ductal Carcinoma In Situ | Not applicable | Not yet recruiting | Hôpital du Valais | 228 | 2026-09-01 | 2026-04-14 |
| SPECTRA: Intraoperative Hyperspectral Imaging for Prostate Cancer HyperSpectral imaging acquisition of ex-vivo prostate specimen prior formalin fixation (fresh acquisition).. - Localized Prostate Cancer, Positive Surgical Margin | Not applicable | Recruiting | Massimo Valerio | 26 | 2026-08-01 | 2026-09-17 |
| A Study to Evaluate the Performance of Confocal Microscopy to Detect Positive Margins During Radical Prostatectomy LaserSAFE - Prostate Cancer, Prostate Cancer (Adenocarcinoma) | Not applicable | Recruiting | University College, London | 693 | 2026-04-20 | 2026-05-18 |
| A Novel Intraoperative Fluorescence-guided System for Evaluating Margins During Breast-conserving Surgery for Breast Cancer EndoSCell Scanner (ES Scanner) System - Breast-Conserving Surgery | Not applicable | Recruiting | Guangdong Provincial People's Hospital | 172 | 2026-04-01 | 2026-06-29 |
| Performance of 18F-FDG Micro-PET-CT in the Assessment of Surgical Margins in Head and Neck Cancer micro PET/CT - Head & Neck Cancer | Not applicable | Completed | Centre Henri Becquerel | 12 | 2025-11-07 | 2026-11-03 |
| Comparative Research on the Accuracy of Margin Interpretation in Breast-Conserving Surgery for Breast Cancer: Cell Microscopic Imaging and Standard Frozen Pathology EndoScell™ intraoperative handheld microscope - Breast-Conserving Surgery, Breast Carcinoma | Not applicable | Not yet recruiting | Peking University Cancer Hospital & Institute | 167 | 2025-07-01 | 2025-06-19 |
| The Comparison of Navigational Bronchoscopic and CT-Guided Preoperative Markings in Minimally Invasive Thoracic Surgery Preoperative marking - VATS, Lung | Not applicable | Completed | Semmelweis University | 66 | 2025-06-01 | 2025-09-05 |
| Feasibility of Timesaving When Using Histolog Confocal Laser Endomicroscopy for Margin Assessment in Prostatectomy Specimen Histolog Scan - Prostate Cancer | Not applicable | Completed | Icahn School of Medicine at Mount Sinai | 78 | 2025-05-13 | 2026-10-13 |
| Safety & Efficacy of a Novel Asymmetrical Linear Stapler (NALS) for Securing Distal Resection Margin in Laparoscopic Rectal Cancer Surgery: Pilot Study Novel asymmetrical linear stapler, Signia™ - Colo-rectal Cancer | Not applicable | Not yet recruiting | Seoul National University Hospital | 60 | 2025-03-01 | 2024-11-29 |
| Robot-assisted Function-sparing Cystectomy Followed by Modified Orthotopic Ileal Neobladder Prostate and seminal-sparing Cystectomy, Conventional Radical Cystoprostatectomy - Negative Surgical Margins | Not applicable | Unknown | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 20 | 2024-06-01 | 2024-05-13 |
| Margin Intraoperative CT Feedback Feedback Study Intraoperative CT of resected lung - Lung Cancer (Diagnosis) | Not applicable | Active not recruiting | University Health Network, Toronto | 80 | 2024-03-06 | 2026-04-28 |
| Dermatoscopy Guided Resection for Skin Cancer Dermatoscopy - Basal Cell Carcinoma, Cutaneous Squamous Cell Carcinoma | Not applicable | Unknown | Region Örebro County | 400 | 2024-01-14 | 2024-04-02 |
| Intraoperative Assessment of Surgical Margins Using Confocal Microscopy in Comparison With Reference Extemporaneous Examination microscopy confocal (Histolog Scanner) - Squamous Cell Carcinoma of Head and Neck, Basal Cell Carcinoma of Skin | Not applicable | Completed | Institut de Cancérologie de Lorraine | 42 | 2023-11-28 | 2026-09-01 |
| Evaluation of Safety and Performance of Intraoperative Detection of Light Signals During Electrosurgical Breast Cancer Resection Clip-on electrode with fiber optics - Breast Cancer, Resection Margin | Not applicable | Completed | Erbe Elektromedizin GmbH | 24 | 2023-09-26 | 2026-04-07 |
| The Application of Probe Confocal Laser Endomicroscopy in Pancreatic Tumor Surgery probe confocal laser endomicroscopy - Pancreatic Cancer, Diagnosis | Not applicable | Unknown | Fudan University | 200 | 2023-09-01 | 2024-03-04 |
| The Value of MRI in Assessing the Status of Retroperitoneal Resection Margin in Colon Cancer Beyond complete mesocolic excision surgery - Colon Cancer | Not applicable | Unknown | Peking University Cancer Hospital & Institute | 29 | 2023-04-02 | 2023-05-16 |
| Combination Topical Cysteamine and Fractional 1927nm Low-Powered Diode Laser for Treatment of Facial Melasma Fractional 1927nm Low-Powered Diode Laser, Topical Cysteamine - Melasma | Not applicable | Unknown | UnionDerm | 20 | 2022-10-28 | 2022-12-19 |
| Intraoperative Use of ClearEdge Device in Breast Conserving Surgery ClearEdge device - Breast Cancer | Not applicable | Unknown | LS BioPath | 288 | 2022-10-10 | 2023-03-22 |
Showing 20 of 42. Sign in to see all of them.
Breast Neoplasms (8) · Recurrence (4) · Carcinoma, Basal Cell (3) · Neoplasms (3) · Prostatic Neoplasms (3) · Squamous Cell Carcinoma of Head and Neck (3) · Carcinoma, Squamous Cell (2) · Colonic Neoplasms (2) · Crohn Disease (2) · Disease (2) · Pancreatic Neoplasms (2) · Rectal Neoplasms (2) · Stomach Neoplasms (2) · Tongue Neoplasms (2)
Morphological and Microscopic Findings (42) · Pathological Conditions, Signs and Symptoms (42) · Neoplasms (29) · Neoplasms by Site (28) · Neoplasms by Histologic Type (12) · Digestive System Diseases (10) · Skin Diseases (10) · Skin and Connective Tissue Diseases (10) · Neoplasms, Glandular and Epithelial (9) · Breast Diseases (8) · Carcinoma (8) · Digestive System Neoplasms (8) · Gastrointestinal Diseases (8) · Pathologic Processes (7) · Gastrointestinal Neoplasms (6)
Microscopy, Confocal (2) · Cysteamine (1) · Dermoscopy (1) · Drug Delivery Systems (1) · Endoscopic Mucosal Resection (1) · Gastrectomy (1) · Narrow Band Imaging (1) · Palliative Care (1) · Ultrasonography (1)
Peking University Cancer Hospital & Institute (2) · Region Örebro County (2) · Samsung Medical Center (2) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (2) · Aarhus University Hospital (1) · Abdelwahab Hashem (1) · Asan Medical Center (1) · Bassem Mohamed Sieda (1) · Centre Henri Becquerel (1) · Centre Hospitalier Universitaire, Amiens (1) · Copenhagen University Hospital, Rigshospitalet (1) · Erbe Elektromedizin GmbH (1) · Fudan University (1) · Guangdong Provincial People's Hospital (1) · Hospital Universitari de Bellvitge (1)
China (8) · United States (7) · South Korea (5) · France (4) · Denmark (2) · Germany (2) · Sweden (2) · Switzerland (2) · Canada (1) · Egypt (1) · Hungary (1) · Italy (1) · Saudi Arabia (1) · Spain (1) · United Kingdom (1)
Amparo Garcia Tejedor, MDPhD (1) · Ashutosh K. Tewari, MD (1) · Brad Schoengood (1) · Byung Joo Chae (1) · Colin Simonson, MD (1) · Greg Shaw, Professor (1) · Han-Sin Jeong, MD PhD (1) · Hui Wang, M.D. (1) · Jasmine Wong, MD (1) · Jian-Kun Hu, M.D. Ph.D. (1) · Johan Knutsson, Assoc. Prof. (1) · Lei Wang, MD, PhD (1) · Lise-Marie Roussel, MD (1) · Lori Laffel, MD, MPH (1)
PMID 16982773, PMID 17960012, PMID 18784101, PMID 21233014, PMID 21437225, PMID 23914987, PMID 24780112, PMID 25049329, PMID 28189914, PMID 28490940, PMID 28533474, PMID 29658848, PMID 29658856, PMID 30171396, PMID 30280658, PMID 30742122, PMID 30875013, PMID 31280965, PMID 31679945, PMID 32221752, PMID 33398548, PMID 33515668, PMID 33538338, PMID 34979601, PMID 36537851, PMID 41663896, PMID 42714336
2025 (1), R01DK046887 (1)