8 recruiting, 6 completed, 2 not yet recruiting, 1 active not recruiting. 9 Not applicable, 2 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 3, Recruiting 3, Not yet recruiting 2, Unknown 1 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Lower Urinary Track Symptoms: new trials by email Literature Review of Lower Urinary Track Symptoms trials Research Report on Lower Urinary Track Symptoms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Holmium Laser Enucleation of the Prostate and Robotic Water Jet Ablation for Benign Prostatic Hyperplasia Device - HoLEP with MOSES 2.0, RWJA with Hydros Robotic System - Benign Prostate Hypertrophy(BPH), Lower Urinary Track Symptoms | Not applicable | Not yet recruiting | The Methodist Hospital Research Institute | 100 | 2026-08-03 | 2026-08-19 |
| SGLT-2 Inhibitors and Lower Urinary Tract Symptoms No Intervention: Observational Cohort - SGLT2 Inhibitors, Lower Urinary Track Symptoms | Active not recruiting | Marmara University | 40 | 2026-07-01 | 2026-07-21 | |
| Silodosin for Urinary Symptoms in Female Patients With Multiple Sclerosis Silodosin 8 mg, Placebo - Multiple Sclerosis, Lower Urinary Track Symptoms | Phase 4 | Recruiting | Atlantic Health System | 60 | 2026-04-01 | 2026-05-29 |
| Turkish Version of the Neurogenic Bladder Symptom Score Short Form Neurogenic Bladder Disorder, Spinal Cord Injury | Completed | Gaziantep Islam Science and Technology University | 120 | 2026-03-27 | 2026-07-23 | |
| Intradetrusor Onabotulinumtoxin A (Botox) at the Time of Transurethral Resection of the Prostate or Transurethral Waterjet Ablation of the Prostate for Mixed Lower Urinary Tract Symptoms Survey using a questionnaire. - Benign Prostatic Hypertrophy (BPH), Lower Urinary Track Symptoms | Recruiting | Benaroya Research Institute | 20 | 2026-01-19 | 2026-01-30 | |
| New Treatment Strategies and Epigenetic Biomarker for Management of Benign Prostatic Hyperplasia raloxifene, Finasteride - BPH (Benign Prostatic Hyperplasia), Lower Urinary Track Symptoms | Phase 2 | Recruiting | Beth Israel Deaconess Medical Center | 242 | 2025-12-03 | 2026-03-23 |
| Outcome and Patient Experiences After Transurethral Resection and Bipolar Enucleation of the Prostate - a Multi-center, Randomized Controlled Trial. Transurethral resection of the prostate., Bipolar enucleation of the prostate - Lower Urinary Track Symptoms, Benign Prostate Obstruction (BPO) | Not applicable | Recruiting | Sykehuset Innlandet HF | 120 | 2025-09-25 | 2026-05-01 |
| e-Sense® Normal Values of Urodynamic Pressures Using e-Sense® Catheters eSense 7Fr Single Sensor Bladder Catheter - Lower Urinary Track Symptoms, Urodynamic Exam | Recruiting | Laborie Medical Technologies Inc. | 40 | 2025-08-15 | 2026-04-29 | |
| Evaluation of the Optilume BPH Catheter System and the Rezum Water Vapor Therapy in Treating Benign Prostatic Hyperplasia Optilume® BPH Catheter System, Rezum Water Vapor Therapy - Benign Prostatic Hyperplasia (BPH), Lower Urinary Track Symptoms | Not applicable | Recruiting | Centre hospitalier de l'Université de Montréal (CHUM) | 100 | 2025-05-09 | 2025-07-17 |
| Low-Energy Shock Wave Therapy for Overactive Bladder in Women With Metabolic Syndrome Low-Energy Extracorporeal Shock Wave Therapy (LiESWT), Sham Shock Wave Therapy - Bladder, Lower Urinary Track Symptoms | Not applicable | Recruiting | KMUHIRB-F(I)-20230051 | 60 | 2025-02-10 | 2026-05-04 |
| Effects of Lumbopelvic Stabilization-based Physiotherapy and Rehabilitation Training in Duchenne Muscular Dystrophy Exercise, Urotherapy - Duchenne Muscular Dystrophy (DMD), Lower Urinary Track Symptoms | Not applicable | Not yet recruiting | Lokman Hekim University | 34 | 2024-12-01 | 2024-10-16 |
| Ejaculation-Preserving Versus Conventional Dual Wavelength Diode Laser Vaporization of the Prostate Conventional dual-wavelength diode laser vaporization of the prostate, Ejaculation-preserving dual wavelength diode laser vaporization of the prostate - Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms | Not applicable | Completed | ALI KAMAL M. SAMI | 119 | 2024-10-05 | 2026-08-20 |
| Turkish Validity and Reliability of the Core Lower Urinary Tract Symptoms Questionnaire in Individuals With Multiple Sclerosis Lower Urinary Track Symptoms, Multiple Sclerosis | Completed | Kutahya Health Sciences University | 71 | 2024-05-15 | 2025-09-05 | |
| Online Adaptive Stereotactic Body Radiotherapy for Localized Prostate Cancer radiotherapy - Localized Prostate Carcinoma, Prostate Cancer (Adenocarcinoma) | Recruiting | University of Zurich | 75 | 2024-03-01 | 2026-07-06 | |
| Urinary CA19-9 Level in the Differential Diagnosis of Neurogenic and Non-Neurogenic Lower Urinary Tract Dysfunction in Children CA19-9 - Lower Urinary Track Symptoms | Not applicable | Unknown | Marmara University | 100 | 2024-01-01 | 2025-01-21 |
| The Effect of DNS-Based Training Combined With PFMT on LUTS and Pelvic Floor Functions in Women With MS Pelvic Floor Muscle Training (PFMT), Pelvic Floor Muscle Training combined with Dynamic Neuromuscular Stabilization (PFMT+DNS) - Women With Multiple Sclerosis, Multiple Sclerosis | Not applicable | Completed | Ondokuz Mayıs University | 24 | 2023-09-01 | 2026-05-06 |
| Long Term Follow up of Water Vapor Thermal Therapy (Rezum) for Benign Prostatic Hyperplasia (BPH) water vapor thermal therapy (Rezum) for prostate - Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms | Not applicable | Completed | Helwan University | 86 | 2021-03-01 | 2025-06-27 |
| Effectiveness of onaBoNT-A vs Oral Tamsulosin in Men With BPH and LUTS onaBoNT-A + placebo, Tamsulosin + placebo - Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms | Phase 2 | Completed | VA Office of Research and Development | 63 | 2012-06-01 | 2021-10-05 |
Prostatic Hyperplasia (8) · Lower Urinary Tract Symptoms (5) · Multiple Sclerosis (4) · Urinary Bladder, Overactive (2) · Adenocarcinoma (1) · Metabolic Syndrome (1) · Muscular Dystrophy, Duchenne (1) · Nocturia (1) · Pelvic Floor Disorders (1) · Prostatic Neoplasms (1) · Retrograde Ejaculation (1) · Spinal Cord Injuries (1) · Urinary Bladder Neck Obstruction (1) · Urinary Bladder, Neurogenic (1)
Male Urogenital Diseases (12) · Urogenital Diseases (12) · Genital Diseases (8) · Genital Diseases, Male (8) · Pathological Conditions, Signs and Symptoms (8) · Prostatic Diseases (8) · Signs and Symptoms (8) · Urological Manifestations (7) · Female Urogenital Diseases (5) · Female Urogenital Diseases and Pregnancy Complications (5) · Nervous System Diseases (5) · Autoimmune Diseases (4) · Autoimmune Diseases of the Nervous System (4) · Demyelinating Autoimmune Diseases, CNS (4) · Demyelinating Diseases (4)
Botulinum Toxins, Type A (1) · Exercise (1) · Finasteride (1) · Radiotherapy (1) · Raloxifene Hydrochloride (1) · Tamsulosin (1) · Transurethral Resection of Prostate (1) · onabotulinum toxin A (1) · silodosin (1)
Marmara University (2) · ALI KAMAL M. SAMI (1) · Atlantic Health System (1) · Benaroya Research Institute (1) · Beth Israel Deaconess Medical Center (1) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · Gaziantep Islam Science and Technology University (1) · Helwan University (1) · KMUHIRB-F(I)-20230051 (1) · Kutahya Health Sciences University (1) · Laborie Medical Technologies Inc. (1) · Lokman Hekim University (1) · Ondokuz Mayıs University (1) · Sykehuset Innlandet HF (1) · The Methodist Hospital Research Institute (1)
Turkey (Türkiye) (6) · United States (5) · Canada (1) · Egypt (1) · Germany (1) · Iraq (1) · Norway (1) · Switzerland (1) · Taiwan (1) · United Kingdom (1)
Aria Olumi, MD (1) · Christopher P Smith, MD (1) · Matthias Guckenberger (1) · Matthias Guckenberger, Prof. Dr. med. (1) · Naeem Bhojani, MD (1) · Tiuri E. Kroese, MD, PhD (1) · Yung-Chin Lee, MD,PHD (1)
PMID 15126771, PMID 18461049, PMID 21791356, PMID 40133731, PMID 40437508
2025 (1), R01DK142211 (1)