2 completed, 2 recruiting, 1 active not recruiting. 2 Phase 1, 1 Early Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 1, Recruiting 1 |
| Early Phase 1 | 1 | Active not recruiting 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Locally Advanced Hypopharyngeal Squamous Cell Carcinoma: new trials by email Literature Review of Locally Advanced Hypopharyngeal Squamous Cell Carcinoma trials Research Report on Locally Advanced Hypopharyngeal Squamous Cell Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Advanced Head and Neck Cancer Who Cannot Receive Cisplatin Biospecimen Collection, Carboplatin, Cetuximab - Locally Advanced Hypopharyngeal Squamous Cell Carcinoma, Locally Advanced Laryngeal Squamous Cell Carcinoma | Phase 3 | Recruiting | NRG Oncology | 454 | 2026-07-31 | 2026-10-27 |
| Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer Biopsy Procedure, Biospecimen Collection, Cisplatin - Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Phase 1 | Recruiting | National Cancer Institute (NCI) | 46 | 2022-09-19 | 2026-09-22 |
| Tolinapant and Radiation for Cisplatin-Ineligible, Previously Untreated, Locally Advanced Head and Neck Cancer Tolinapant, Radiation Therapy - Head and Neck Carcinoma of Unknown Primary, Locally Advanced Head and Neck Squamous Cell Carcinoma | Early Phase 1 | Active not recruiting | Emory University | 10 | 2022-02-17 | 2026-08-21 |
| Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer Proton Beam Radiation Therapy, Quality-of-Life Assessment, Questionnaire Administration - Locally Advanced Head and Neck Squamous Cell Carcinoma, Locally Advanced Hypopharyngeal Squamous Cell Carcinoma | Phase 1 | Completed | M.D. Anderson Cancer Center | 3 | 2020-10-19 | 2024-10-29 |
| Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin Cisplatin, Hearing Handicap Inventory for Adults - Screening, Radiation Therapy - Clinical Stage III Human Papillomavirus (HPV)-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Phase 2 | Completed | Hyunseok Kang, MD | 16 | 2020-10-14 | 2024-06-28 |
Carcinoma (3) · Hypopharyngeal Neoplasms (3) · Laryngeal Neoplasms (3) · Mouth Neoplasms (2) · Oropharyngeal Neoplasms (2) · Nasopharyngeal Carcinoma (1)
Head and Neck Neoplasms (3) · Laryngeal Diseases (3) · Neoplasms (3) · Neoplasms by Histologic Type (3) · Neoplasms by Site (3) · Neoplasms, Glandular and Epithelial (3) · Otorhinolaryngologic Diseases (3) · Otorhinolaryngologic Neoplasms (3) · Pharyngeal Diseases (3) · Pharyngeal Neoplasms (3) · Respiratory Tract Diseases (3) · Respiratory Tract Neoplasms (3) · Stomatognathic Diseases (3) · Mouth Diseases (2) · Nasopharyngeal Diseases (1)
Radiation (3) · Radiotherapy (3) · 1,2-diaminocyclohexaneplatinum II citrate (2) · Cisplatin (2) · Magnetic Resonance Spectroscopy (2) · Specimen Handling (2) · (225)Ac-DOTA-c(RGDyK) (1) · ASTX-660 (1) · Biopsy (1) · Carboplatin (1) · Cetuximab (1) · Paclitaxel (1) · Platinum (1) · Proton Therapy (1) · Protons (1)
Emory University (1) · Hyunseok Kang, MD (1) · M.D. Anderson Cancer Center (1) · NRG Oncology (1) · National Cancer Institute (NCI) (1)
United States (5) · Canada (1)
Clifton D Fuller (1) · Hyunseok Kang, MD (1) · Loren K Mell (1) · Malcolm D Mattes (1) · Nicole C Schmitt, MD (1)
P30CA138292 (1), U10CA180868 (1), UM1CA186644 (1)