4 completed, 2 not yet recruiting, 2 recruiting, 1 no longer available. 3 Phase 2, 2 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 1, Not yet recruiting 1, Recruiting 1 |
| Not applicable | 2 | Completed 1, Recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Leprosy, Multibacillary: new trials by email Literature Review of Leprosy, Multibacillary trials Research Report on Leprosy, Multibacillary
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Telacebec in Adults With Multibacillary Leprosy (TEBULA Leprosy Trial) Telacebec 300 mg, Telacebec 600 mg, Telacebec + Rifampicine - Leprosy, Multibacillary | Phase 2 | Not yet recruiting | Fondation Raoul Follereau | 120 | 2026-12-01 | 2026-11-05 |
| Epidemiological, Clinical, Diagnostic, and Therapeutic Characteristics of Hansen's Disease in Costa Rica (2018-2025) Leprosy, Hansen's Disease | Not yet recruiting | Caja Costarricense de Seguro Social | 130 | 2026-05-01 | 2026-03-09 | |
| Accuracy of the Polymerase Chain Reaction of Ulnar Perineural Subcutaneous Aspirate Guided by Ultrasound for the Diagnosis and Monitoring of Leprosy Cure Ultrasound-Guided Ulnar Perineural Subcutaneous Aspirate - Leprosy, Leprosy Neuropathy | Not applicable | Recruiting | University of Brasilia | 108 | 2026-01-01 | 2026-04-07 |
| Serum Irisin Level In Leprosy Patients Serum Irisin - Leprosy | Completed | Aswan University | 58 | 2024-01-01 | 2024-11-08 | |
| Efficacy and Tolerability of Adjunct Metformin for Multibacillary Leprosy Metformin, Placebo - Leprosy, Leprosy, Multibacillary | Phase 2 | Recruiting | Oxford University Clinical Research Unit Indonesia | 166 | 2022-10-01 | 2025-08-07 |
| A Study to Evaluate the Efficacy and Safety of Bedaquiline (TMC207) in Participants With Multibacillary Leprosy Bedaquiline 200 mg - Leprosy, Multibacillary | Phase 2 | Completed | Janssen Research & Development, LLC | 11 | 2018-09-26 | 2024-02-02 |
| Effect of Additional Clofazimine on Erythema Nodosum Leprosum (ENL) Reactions in Leprosy Clofazimine, Placebo - Borderline Lepromatous Leprosy, Lepromatous Leprosy | Phase 4 | Completed | Paul Saunderson | 100 | 2010-08-01 | 2015-06-04 |
| Microcirculatory Impairment in Patients With Leprosy acetylcholine Iontophoresis, sodium nitroprusside Iontophoresis - Lepromatous Leprosy | Not applicable | Completed | Curt Treu | 20 | 2006-03-01 | 2014-03-12 |
| Treatment Protocol for Clofazamine in the Long Term Treatment of Leprosy clofazamine - Leprosy | No longer available | Kaiser Permanente | 2015-04-03 |
Leprosy (8) · Leprosy, Lepromatous (4) · Leprosy, Tuberculoid (1) · Mononeuropathies (1) · Neglected Diseases (1) · Neurologic Manifestations (1) · Polyneuropathies (1)
Actinomycetales Infections (9) · Bacterial Infections (9) · Bacterial Infections and Mycoses (9) · Gram-Positive Bacterial Infections (9) · Infections (9) · Mycobacterium Infections (9) · Mycobacterium Infections, Nontuberculous (9) · Nervous System Diseases (2) · Pathological Conditions, Signs and Symptoms (2) · Disease Attributes (1) · Leprosy (1) · Leprosy, Paucibacillary (1) · Neuromuscular Diseases (1) · Pathologic Processes (1)
Clofazimine (1) · Metformin (1) · Rifampin (1) · Vitamins (1) · bedaquiline (1) · telacebec (1)
Aswan University (1) · Caja Costarricense de Seguro Social (1) · Curt Treu (1) · Fondation Raoul Follereau (1) · Janssen Research & Development, LLC (1) · Kaiser Permanente (1) · Oxford University Clinical Research Unit Indonesia (1) · Paul Saunderson (1) · University of Brasilia (1)
Brazil (2) · Benin (1) · Costa Rica (1) · Egypt (1) · Indonesia (1) · Philippines (1) · United States (1)
Arnold M Henson, MD (1) · Eliete Bouskela, PhD (1) · Hardiyanto Soebono, Prof.Dr.dr (1) · Marivic Balagon, MD (1) · Moustafa El Taieb, Professor (1)