25 completed, 7 recruiting, 4 unknown, 3 terminated. 11 Not applicable, 11 Phase 2, 5 Phase 1, 5 Phase 3, 1 Early Phase 1.
Follow Larynx Cancer: new trials by email Literature Review of Larynx Cancer trials Research Report on Larynx Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CApecitabine Prior to TUmor Resection in Ent Oncology (CAPTURE) Capecitabine, Standard of Care (SOC) - Head Neck Cancer, Mouth Cancer | Phase 2 | Not yet recruiting | Sir Mortimer B. Davis - Jewish General Hospital | 75 | 2026-01-01 | 2025-11-28 |
| A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC) Sacituzumab Govitecan, Cetuximab - Squamous Cell Carcinoma of Head and Neck, Sinus Cancer | Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 40 | 2025-07-02 | 2026-02-19 |
| Lymphocyte-Sparing And Radio-Immunotherapy in Head and Neck Carcinoma Vesanoid, Standard radiotherapy, Tailored radiotherapy - Oropharynx Cancer, Larynx Cancer | Phase 3 | Recruiting | Centre Leon Berard | 460 | 2025-02-20 | 2026-04-24 |
| Evaluations of Alcohol Warning Labels Narrative pictorial warning labels for alcoholic beverages, Non-narrative pictorial warning labels for alcoholic beverages - Oral Cancer, Esophageal Cancer | Not applicable | Completed | University of Connecticut | 1053 | 2024-01-19 | 2025-11-14 |
| A Study of Concurrent Chemoradiation in Combination With or Without PD1 Inhibitor AB122 Adenosine 2a Receptor / Adenosine 2b Receptor Inhibitor AB928 Therapies in Locally Advanced Head and Neck Cancers Zimberelimab, Etrumadenant, Cisplatin - Head and Neck Cancer, Squamous Cell Carcinoma of Head and Neck | Phase 1 | Withdrawn | Jennifer Choe | 2023-12-31 | 2023-11-30 | |
| Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy ENDURE - Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma | Not applicable | Recruiting | Medical University of South Carolina | 532 | 2023-10-30 | 2025-12-11 |
| Neoadjuvant Chemoimmunotherapy Followed By Radiation Or Organ Preservation Surgery In Laryngeal/Hypopharyngeal Cancer Surgery, Radiation, Toripalimab - Larynx Cancer, Hypopharyngeal Cancer | Phase 2 | Recruiting | Fudan University | 82 | 2023-08-22 | 2023-09-15 |
| GI Organ Tracking Via Balloon Applicators Balloon-tipped catheter - Esophageal Cancer, Kidney Cancer | Not applicable | Withdrawn | Washington University School of Medicine | 2023-04-25 | 2024-06-13 | |
| The ENHANCE Study: Exercise and Nutrition in Head And Neck CancEr Survivors ENHANCE Intervention - Exercise and Nutrition, ENHANCE Intervention - Nutrition Only - Oral Cavity Cancer, Oropharynx Cancer | Not applicable | Completed | H. Lee Moffitt Cancer Center and Research Institute | 40 | 2023-04-06 | 2026-09-17 |
| Phonatory Movement of the Pharyngoesophageal Mucosa in Laryngectomy Patients High-speed video endoscopy (HSV), Acoustic voice analysis, Quality of life questionnaire - Larynx Cancer, Laryngectomy; Status | Completed | Osijek University Hospital | 55 | 2022-08-01 | 2026-03-31 | |
| Immunological Function After Radiation With Either Proton or Photon Therapy blood draws - HNSCC, Head and Neck Cancer | Unknown | University Medical Center Groningen | 40 | 2021-09-23 | 2023-08-30 | |
| Evaluation of the French Translation of Swallowing (SOAL-VF) Patient Reported Outcomes (PRO) After Total PharyngoLaryngectomy Pharyngeal Cancer, Swallowing Disorder | Completed | Centre Hospitalier de Valence | 225 | 2021-07-03 | 2025-09-08 | |
| Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy HNSCC, Oral Cavity Cancer | Recruiting | University Hospital Freiburg | 1500 | 2021-06-01 | 2025-03-25 | |
| The Registry of Oncology Outcomes Associated With Testing and Treatment Biomarker Testing (L), Systemic Treatment (T), Patient Reported Outcomes (P) - Adenocarcinoma, Adenocystic Carcinoma | Completed | Taproot Health | 167 | 2021-05-05 | 2024-12-18 | |
| Quality of Life and Voice Perception in Patients Laryngoctomized Phonatory Wearers to assess the voice perception of the patient undergoing phonatory prosthesis placement surgery by evaluating the optimal score (>30) in terms of VHI. - Quality of Life, Larynx Cancer | Unknown | Regina Elena Cancer Institute | 31 | 2021-05-04 | 2023-10-17 | |
| CONFIRM: Magnetic Resonance Guided Radiation Therapy Viewray MRIdian® Linac - Gastric Cancer, Invasive Breast Cancer | Not applicable | Recruiting | Brigham and Women's Hospital | 70 | 2021-05-01 | 2026-02-09 |
| Bilateral Elective Neck Dissection in Salvage Total Laryngectomy Elective bilateral neck dissection in cN0 patients - Neck Cancer, Larynx | Completed | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 80 | 2020-09-01 | 2023-02-28 | |
| VoiceS: Voice Quality After Transoral CO2-Laser Surgery Versus Single Vocal Cord Irradiation for Larynx Cancer Single Vocal Cord Irradiation (SVCI), Arm A: Transoral CO2-Laser Microsurgical Cordectomy (TLM) - Glottis Tumor, Larynx Cancer | Not applicable | Recruiting | Olgun Elicin | 34 | 2019-11-20 | 2025-10-07 |
| Vocal-cord vs. Complete Laryngeal Radiotherapy for Early Glottic Cancer Vocal-cord Radiotherapy, Complete Larynx Radiotherapy - Cancer Neck, Larynx Cancer | Phase 2 | Active not recruiting | Centre hospitalier de l'Université de Montréal (CHUM) | 155 | 2018-10-11 | 2025-03-21 |
| Comparison Between a Standard Tube and the Ultra-thin Tritube for Intubation of the Trachea and for Maintaining Access to the Trachea After Anaesthesia, in Patients With an Expected Difficult Direct Laryngoscopy Tritube, Standard enditracheal tube - Oral Neoplasm, Pharynx Cancer | Not applicable | Completed | Michael Seltz Kristensen | 48 | 2018-09-12 | 2024-02-29 |
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Laryngeal Neoplasms (44) · Mouth Neoplasms (18) · Head and Neck Neoplasms (16) · Hypopharyngeal Neoplasms (16) · Oropharyngeal Neoplasms (16) · Squamous Cell Carcinoma of Head and Neck (11) · Pharyngeal Neoplasms (7) · Esophageal Neoplasms (5) · Stomach Neoplasms (4) · Carcinoma, Squamous Cell (3) · Colonic Neoplasms (3) · Laryngeal Diseases (3) · Lip Neoplasms (3) · Liver Neoplasms (3) · Lung Neoplasms (3)
Neoplasms by Site (44) · Otorhinolaryngologic Diseases (44) · Otorhinolaryngologic Neoplasms (44) · Respiratory Tract Diseases (44) · Respiratory Tract Neoplasms (44) · Neoplasms (43) · Laryngeal Diseases (41) · Head and Neck Neoplasms (28) · Stomatognathic Diseases (27) · Pharyngeal Diseases (25) · Mouth Diseases (19) · Pharyngeal Neoplasms (18) · Carcinoma (16) · Neoplasms by Histologic Type (16) · Neoplasms, Glandular and Epithelial (16)
Cisplatin (8) · Cetuximab (4) · Fluorouracil (3) · Radiation (3) · Carboplatin (2) · Docetaxel (2) · Laryngoscopy (2) · Surveys and Questionnaires (2) · pembrolizumab (2) · 130-nm albumin-bound paclitaxel (1) · 5-fluoro-3-pyridinecarboxylic acid (1) · Albumin-Bound Paclitaxel (1) · Alcoholic Beverages (1) · Biological Therapy (1) · Blood Specimen Collection (1)
Groupe Oncologie Radiotherapie Tete et Cou (3) · Memorial Sloan Kettering Cancer Center (3) · Gustave Roussy, Cancer Campus, Grand Paris (2) · Atos Medical AB (1) · Brigham and Women's Hospital (1) · Centre Hospitalier de Valence (1) · Centre Leon Berard (1) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · Christian von Buchwald (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Fudan University (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Hacettepe University (1) · Jennifer Choe (1) · Klus Pharma Inc. (1)
United States (18) · France (8) · Netherlands (4) · Denmark (2) · Germany (2) · Italy (2) · Switzerland (2) · Australia (1) · Belgium (1) · Canada (1) · China (1) · Croatia (1) · Cyprus (1) · Czechia (1) · India (1)
Aron Popovtzer, MD (1) · Assuntina Sacco, M.D. (1) · Brett Miles, MD (1) · C. Jillian Tsai, MD (1) · Christian Von Buchwald, MD, DMSc (1) · David I Fielding, FRACP MD (1) · David Palma (1) · Dennis Kraus, MD (1) · Edward J. Damrose MD, FACS (1) · Evan M Graboyes, MD, MPH (1) · Frank Hoebers, MD,PhD (1) · Frans JM Hilgers, MD, PhD (1)
PMID 21831465, PMID 23341517, PMID 29149611, PMID 30663068, PMID 32479189, PMID 33888069, PMID 33989559, PMID 36303192, PMID 40597116, PMID 40692081
2015 (1), R01CA282165 (1), R03CA273391 (1)