35 completed. 35 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 35 | Completed 35 |
Follow Keratosis: new trials by email Literature Review of Keratosis trials Research Report on Keratosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Combination Therapy of 5-Fluorouracil and CALcipotriol Versus 5-Fluorouracil in the Treatment of Actinic Keratosis 5FU-Calcipotriol, 5-FU 50 MG/ML Topical Cream - Actinic Keratoses | Phase 4 | Completed | Maastricht University Medical Center | 232 | 2024-09-04 | 2026-10-29 |
| Trial Assessing the Impact on Facial Skin Quality, Hydration, and Skin Barrier of Three (3) Hydrafacial Treatments in Adults of All Skin Types. HydraFacial Syndeo System, ReGen-GF, HydraFacial Elite MD System - Cutis Laxa Facialis, Xeroderma | Phase 4 | Completed | Austin Institute for Clinical Research | 27 | 2023-11-20 | 2024-10-24 |
| Tirbanibulin 1% Ointment for the Treatment of Chronically Sun-damaged Skin on the Face Tirbanibulin - Actinic Keratosis | Phase 4 | Completed | Medical University of Graz | 22 | 2023-05-11 | 2023-11-14 |
| A Study of Tirbanibulin on the Wellbeing of Participants With Actinic Keratoses Tirbanibulin 2.5 mg ointment - Actinic Keratosis | Phase 4 | Completed | Almirall, S.A. | 334 | 2023-01-20 | 2025-02-20 |
| Earliest Stage Treatment of Aktinic Keratosis With Imiquimod 3.75% Cream Imiquimod 3.75% Cream - Actinic Keratoses | Phase 4 | Completed | Medical University of Graz | 48 | 2021-04-16 | 2022-01-11 |
| Frequency and Intensity of Local Reactions in Patients Treated With 4% 5-FU vs 4% 5-FU Associated With an Emollient Cream: a Randomised, Controlled Clinical Trial 5-fluorouracil 4% (Tolak), Dexeryl - Actinic Keratoses | Phase 4 | Completed | Pierre Fabre Medicament | 146 | 2021-02-16 | 2022-09-19 |
| Menthol for PDT Pain Relief Menthol, Aqueous Cream - Actinic Keratosis | Phase 4 | Completed | University of Dundee | 10 | 2018-10-23 | 2021-03-09 |
| An A Study Assessing Subject Satisfaction With A-101 Topical Solution for Seborrheic Keratoses A-101 Topical Solution - Seborrheic Keratosis | Phase 4 | Completed | Aclaris Therapeutics, Inc. | 41 | 2018-03-21 | 2019-10-02 |
| Evaluating Skin Appearance Following 5-Flourouracil Cream for Treatment of Actinic Keratosis and the Effects of Topical Agents Topical Steroid Ointment, Vaseline, Skin Barrier Moisturier - Actinic Keratoses | Phase 4 | Completed | University of Arizona | 30 | 2017-10-10 | 2019-06-25 |
| PRO With Luxerm® in the Field Treatment of Thin and Non-hyperkeratotic Non-pigmented AK Methyl Aminolaevulinate 16% Cream - Actinic Keratoses | Phase 4 | Completed | Galderma R&D | 50 | 2017-06-07 | 2021-02-18 |
| Photodynamic Therapy of Actinic Keratosis of the Face and Scalp With and Without Prior Curettage No curettage, Curettage - Keratosis, Actinic | Phase 4 | Completed | Bispebjerg Hospital | 25 | 2017-06-01 | 2018-10-09 |
| Efficacy of Ingenol Mebutate on Actinic Keratoses and Field Cancerization vs Cryotherapy Ingenol mebutate, cryotherapy - Actinic Keratosis | Phase 4 | Completed | University of Campania Luigi Vanvitelli | 50 | 2017-04-12 | 2019-09-24 |
| Efficacy of Ablative Fractional Laser-assisted Photodynamic Therapy According to the Laser Density for Actinic Keratosis lidocaine/prilocaine (5%) application, 2940-nm Er:YAG AFL pretreatment, MAL application - Actinic Keratosis | Phase 4 | Completed | Dong-A University | 47 | 2017-02-01 | 2018-11-06 |
| Safety and Efficacy of Ingenol Mebutate Gel 0.015% for Treatment of AK on the Face in Solid Organ Transplant Recipients ingenol mebutate gel 0.015% - Actinic Keratosis | Phase 4 | Completed | University of California, San Francisco | 20 | 2016-10-06 | 2022-03-09 |
| Daylight-PDT With MAL for AK and Photodamaged Skin Daylight photodynamic therapy using Methylaminolevulinate (MAL), Cryosurgery - Actinic Keratoses, Photodamaged Skin | Phase 4 | Completed | University Hospital Regensburg | 58 | 2016-03-03 | 2020-11-09 |
| Bilateral Comparison of Treatment of Facial Actinic Keratoses Using Microneedling and Photodynamic Therapy With Aminolevulinic Acid and Blue Light Versus Photodynamic Therapy With Aminolevulinic Acid and Blue Light Using Two Incubation Times Aminolevulinic Acid (ALA), Environ Cosmetic Roller, BLU-U IIlluminator - Actinic Keratoses | Phase 4 | Completed | Dermatology, Laser & Vein Specialists of the Carolinas | 10 | 2015-10-01 | 2017-07-19 |
| Daylight PDT for Actinic Keratoses: a Multicentre Study Comparing Two Photosensitizers (BF-200 ALA Versus MAL) Aminolevulinic Acid, Methyl 5-aminolevulinate - Actinic Keratosis, Natural Daylight Photodynamic Therapy | Phase 4 | Completed | Joint Authority for Päijät-Häme Social and Health Care | 72 | 2015-06-01 | 2019-08-28 |
| Efficacy and Safety of Ingenol Mebutate Gel 0.015% Compared to Diclofenac Sodium Gel 3% in Subjects With Actinic Keratoses on the Face or Scalp Ingenol Mebutate Gel, 0.015%, Diclofenac sodium gel 3% - Actinic Keratosis (AK) | Phase 4 | Completed | LEO Pharma | 502 | 2015-04-01 | 2025-02-24 |
| Study of Daylight Photodynamic Therapy With Aminolevulinic Acid for Actinic Keratoses Aminolevulinic Acid - Actinic Keratosis | Phase 4 | Completed | University of California, Irvine | 30 | 2015-04-01 | 2024-06-27 |
| Clinical Trial of Ingenol Mebutate Gel 0.015% & 0.05% in Actinic Keratosis ingenol mebutate gel 0.015%, ingenol mebutate gel 0.05% - Actinic Keratosis | Phase 4 | Completed | Korea University | 77 | 2015-04-01 | 2018-04-18 |
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Keratosis, Actinic (33) · Ichthyosis (1) · Keratosis, Seborrheic (1) · Photosensitivity Disorders (1)
Skin Diseases (35) · Skin and Connective Tissue Diseases (35) · Neoplasms (33) · Precancerous Conditions (33) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Infant, Newborn, Diseases (1) · Skin Abnormalities (1)
Imiquimod (7) · 3-ingenyl angelate (5) · Diclofenac (5) · Aminolevulinic Acid (3) · Fluorouracil (3) · Cryosurgery (2) · Cryotherapy (2) · methyl 5-aminolevulinate (2) · tirbanibulin (2) · BF-200 ALA (1) · Bacitracin (1) · Biafine (1) · Curettage (1) · Lidocaine (1) · Menthol (1)
Galderma R&D (2) · Graceway Pharmaceuticals, LLC (2) · LEO Pharma (2) · MEDA Pharma GmbH & Co. KG (2) · Medical University of Graz (2) · University Hospital Regensburg (2) · Wake Forest University (2) · Aclaris Therapeutics, Inc. (1) · Almirall, S.A. (1) · Austin Institute for Clinical Research (1) · Bispebjerg Hospital (1) · Derm Research @ 888 Inc. (1) · Dermatology, Laser & Vein Specialists of the Carolinas (1) · Dong-A University (1) · Goldman, Butterwick, Fitzpatrick and Groff (1)
United States (14) · Germany (9) · Austria (4) · France (3) · Italy (3) · United Kingdom (3) · South Korea (2) · Spain (2) · Canada (1) · Denmark (1) · Finland (1) · Netherlands (1)
Steve Feldman, MD, PhD (2) · Alberto Lecchi (1) · Christopher B Zachary, MBBS. FRC[ (1) · Claus Garbe, MD (1) · Darrell S Rigel, MD (1) · David Gordon, MD (1) · Edward Lain, MD, MBA (1) · Eggert Stockfleth, Prof.Dr.med. (1) · Gary Goldenberg, MD (1) · Giuseppe Argenziano, Prof (1) · Harald Gollnick, MD, Prof. (1) · Harald Gollnick, Prof. Dr. (1) · Ida Knutar, Lic. Med. (1) · Ilhwan Kim, MD (1)
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