4 completed, 4 recruiting, 2 not yet recruiting, 1 terminated. 3 Not applicable, 2 Phase 2, 2 Phase 3, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Recruiting 2, Completed 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 1, Terminated 1 |
| Phase 4 | 2 | Not yet recruiting 2 |
Follow Internal Hemorrhoids: new trials by email Literature Review of Internal Hemorrhoids trials Research Report on Internal Hemorrhoids
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Polidocanol Foam Sclerotherapy in Symptomatic Internal Hemorrhoids: A Prospective Study Standardized 3% Polidocanol Foam Sclerotherapy - Internal Piles Sclerotherapy, Internal Hemorrhoids | Phase 4 | Not yet recruiting | Radwa Hussein Mohammed Hasanen | 130 | 2026-10-01 | 2026-10-08 |
| HELO Trial: Energy-Based Therapies vs. Conventional Hemorrhoidectomy for Grade III Hemorrhoids Laser Hemorrhoidoplasty (LHP), Hemorrhoid Energy Therapy (HET), Ferguson Hemorrhoidectomy - Hemorrhoids Third Degree, Internal Hemorrhoids | Not applicable | Recruiting | Chang Gung Memorial Hospital | 60 | 2026-07-01 | 2026-08-07 |
| Clinical Outcomes After Laser Hemorrhoidoplasty Laser Hemorrhoidoplasty - Hemorrhoidal Disease, Internal Hemorrhoids | Recruiting | Sanliurfa Education and Research Hospital | 60 | 2026-06-01 | 2026-07-09 | |
| Nitroglycerin Ointment for Pain Relief After Endoscopic Hemorrhoid Band Ligation Nitroglycerin Ointment, Placebo Ointment - Internal Hemorrhoids, Postoperative Pain After Endoscopic Rubber Band Ligation | Phase 4 | Not yet recruiting | Ying Zhu | 68 | 2026-02-01 | 2026-02-05 |
| Prospective HemorrhoIdaL EmboliSation (PILES) Registry Hemorrhoid Artery Embolization - Hemorrhoid, Internal Hemorrhoids | Recruiting | Joint & Vascular Institute | 1200 | 2026-01-18 | 2026-06-12 | |
| Comparison of Laser Hemorrhoidoplasty Versus Conventional Milligan Morgan Hemorrhoidectomy in Grade II and III Hemorrhoids Laser Hemorrhoidoplasty, Milligan Morgan Hemorrhoidectomy - Hemorrhoids Second Degree, Hemorrhoids Third Degree | Not applicable | Completed | Allama Iqbal Medical College | 96 | 2025-09-01 | 2026-07-01 |
| Hemorrhoidal Artery Embolization: Longitudinal Impact On Symptoms (HELIOS) Hemorrhoidal artery embolization - Internal Hemorrhoids, HAE | Not applicable | Recruiting | University of California, Los Angeles | 22 | 2025-08-05 | 2026-02-02 |
| Evaluate Safety and Efficacy of 25 mg Hydrocortisone Acetate Suppositories in Treatment of Internal Hemorrhoids Hydrocortisone Acetate Suppository, 25 mg (Nivagen), Placebo (Vehicle) Suppository (Nivagen) - Internal Hemorrhoids | Phase 2 | Completed | Nivagen Pharmaceuticals Inc. | 103 | 2019-02-12 | 2022-09-13 |
| Safety and Efficacy Study of Anucort HC TM 25mg Rectal Suppositories to Treat Symptomatic Internal Hemorrhoids Anucort-HC, 25 Mg Rectal Suppository, Placebo suppository - Internal Hemorrhoids | Phase 2 | Completed | G & W Laboratories Inc. | 150 | 2013-10-01 | 2016-11-03 |
| Efficacy and Safety Study to Treat Subjects With Symptomatic Internal Hemorrhoids Iferanserin, Placebo, Iferanserin + Placebo - Internal Hemorrhoids | Phase 3 | Terminated | Ventrus Biosciences, Inc | 403 | 2011-07-01 | 2014-01-28 |
| Study About Patient Comfort and Long-term Outcome After Stapled Hemorrhoidopexy Stapled hemorrhoidopexy, Milligan Morgan - Internal Hemorrhoids | Phase 3 | Completed | Universitätsklinikum Hamburg-Eppendorf | 130 | 2000-07-01 | 2012-02-15 |
Pain, Postoperative (3) · Hemorrhoids (2) · Patient Satisfaction (2) · Hemorrhage (1)
Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Neurologic Manifestations (3) · Pain (3) · Postoperative Complications (3) · Signs and Symptoms (3) · Behavior (2) · Cardiovascular Diseases (2) · Digestive System Diseases (2) · Gastrointestinal Diseases (2) · Health Behavior (2) · Intestinal Diseases (2) · Rectal Diseases (2) · Treatment Adherence and Compliance (2) · Vascular Diseases (2)
Suppositories (2) · Hydrocortisone (1) · iferanserin (1)
Allama Iqbal Medical College (1) · Chang Gung Memorial Hospital (1) · G & W Laboratories Inc. (1) · Joint & Vascular Institute (1) · Nivagen Pharmaceuticals Inc. (1) · Radwa Hussein Mohammed Hasanen (1) · Sanliurfa Education and Research Hospital (1) · University of California, Los Angeles (1) · Universitätsklinikum Hamburg-Eppendorf (1) · Ventrus Biosciences, Inc (1) · Ying Zhu (1)
United States (5) · India (1) · Pakistan (1) · Taiwan (1) · Turkey (Türkiye) (1)
Allan G Coates, DO (1) · Anand Shukla, MS, MBA, (1) · Cleveland Clinic (1) · Jakob R Izbicki, MD (1) · Lucas Cusumano, MD (1) · Vedat Kaplan (1)