16 completed, 2 not yet recruiting, 2 terminated, 1 unknown. 5 Phase 1, 5 Phase 2, 4 Not applicable, 3 Phase 3, 3 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 4, Terminated 1 |
| Phase 2 | 5 | Completed 5 |
| Not applicable | 4 | Completed 3, Unknown 1 |
| Phase 3 | 3 | Completed 3 |
| Phase 4 | 3 | Not yet recruiting 2, Terminated 1 |
| Early Phase 1 | 1 | Completed 1 |
Follow Suppositories: new trials by email Literature Review of Suppositories trials Research Report on Suppositories
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pain Control During Hysterosalpingography: A Three-Arm Randomized Trial Indomethacin 100Mg Suppository, Lidocaine %2 ampoule - Hysterosalpingography-Related Pain | Phase 4 | Not yet recruiting | Balikesir University | 180 | 2026-11-01 | 2026-10-15 |
| Preoperative Indomethacin and Paracetamol for Pain Management During Oocyte Retrieval in IVF Patients Indomethacin 100Mg Suppository, Paracetamol / Acetaminophen - Pain, Oocyte Retrieval | Phase 4 | Not yet recruiting | Western Galilee Hospital-Nahariya | 177 | 2026-04-13 | 2026-05-04 |
| Efficacy and Safety of Natamycin and Lactulose Vaginal Suppositories in Treatment of Vulvovaginal Candidiasis Natamycin + Lactulose 100 mg + 300 mg vaginal suppositories, Lactulose 300 mg vaginal suppositories, Pimafucin® (natamycin) 100 mg vaginal suppositories - Vulvovaginal Candidiasis, Genital | Phase 3 | Completed | Avva Rus, JSC | 218 | 2022-12-29 | 2024-05-13 |
| Gemeprost Versus Dinoprostone in First Trimester Miscarriages Gemeprost 1 Mg Vaginal Pessary, Dinoprostone 3 mg - Missed Abortion, Medical; Abortion, Fetus | Phase 2 | Completed | National University of Malaysia | 101 | 2022-11-11 | 2025-06-11 |
| Hormonal Monitoring and Progesterone Adjustment in Frozen Embryo Transfer Cycles estradiol valerate, Hormonal monitoring progesterone, estradiol, luteinizing hormone, transvaginal ultrasound examination - Female Infertility | Not applicable | Completed | Alexandria University | 600 | 2019-10-01 | 2024-02-02 |
| Evaluate Safety and Efficacy of 25 mg Hydrocortisone Acetate Suppositories in Treatment of Internal Hemorrhoids Hydrocortisone Acetate Suppository, 25 mg (Nivagen), Placebo (Vehicle) Suppository (Nivagen) - Internal Hemorrhoids | Phase 2 | Completed | Nivagen Pharmaceuticals Inc. | 103 | 2019-02-12 | 2022-09-13 |
| Baclofen/Diazepam Supps for Treatment of Pelvic Floor Myalgia Baclofen/diazepam, Vaginal placebo - Pelvic Floor Dyssynergia | Not applicable | Unknown | Dr. John A. Thiel Medical Professional Corporation | 60 | 2018-09-01 | 2018-06-07 |
| Indomethacin Prior to Difficult Embryo Transfer is it a Solution? Indomethacin 100Mg Suppository, IVF/ICSI - Difficult Embryo Transfer | Phase 3 | Completed | Cairo University | 200 | 2018-06-02 | 2018-12-14 |
| Idronoxil Suppository Combine With Radiotherapy for Metastatic Prostate Cancer idronoxil (NOX66) suppository, Stereotactic Body Radiation Therapy - Metastatic Castrate- Resistant Prostate Cancer | Phase 1 | Terminated | Royal North Shore Hospital | 1 | 2017-08-31 | 2022-05-11 |
| Effectiveness of Bisacodyl Suppository Agent for Dose Reduction of Low Dose PEG 2L PEG-Asc, Bisacodyl 10Mg Suppository, 1L PEG-Asc - Bowel Preparation | Not applicable | Completed | Samsung Medical Center | 168 | 2017-07-31 | 2019-02-21 |
| Naloxegol to Prevent Lower Gastrointestinal Paralysis in Critically Ill Adults Administered Opioids Naloxegol Oral Tablet, Placebo Oral Tablet, Docusate Sodium 100 Mg oral capsule [Colace] - Constipation | Phase 4 | Terminated | Tufts Medical Center | 12 | 2017-01-01 | 2023-02-16 |
| Tolerability and Pharmacokinetic Study of Econazole Nitrate Plus Benzydamine HCl Vaginal Pessary Econazole nitrate 150 mg plus Benzydamine HCl 6 mg vaginal pessary, Placebo plus Econazole nitrate 150 mg vaginal pessary, Placebo plus Benzydamine HCl 6 mg vaginal pessary - Healthy Women | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 49 | 2016-03-04 | 2017-02-07 |
| Comparison Between Rectal Suppository Acetaminophen and Diclofenac Sodium as Analgesia for Postpartum Perineal Tear Diclofenac Sodium 50Mg Suppository, Paracetamol 500Mg Suppository - Perineal Tear, Perineal Laceration (Obstetric) | Phase 2 | Completed | Clinical Research Centre, Malaysia | 909 | 2015-10-01 | 2017-02-03 |
| Screening for Colorectal Cancer in Average and High Risk Population FIT, Precolonoscopy cleansing regimen, Conventional Colonoscopy - Colorectal Neoplasms, Colorectal Cancer | Early Phase 1 | Completed | Lewai Sharki Abdulaziz, MSc PhD | 537 | 2015-04-01 | 2019-09-04 |
| Pharmacokinetic Study Comparing Topical, Rectal, and Oral Quetiapine Quetiapine 25 mg gel applied topically, Quetiapine 25 mg tablet by mouth, Quetiapine 25 mg rectal suppository - Dementia, Delirium | Phase 1 | Completed | Mayo Clinic | 10 | 2014-06-01 | 2017-04-25 |
| Safety and Efficacy Study of Anucort HC TM 25mg Rectal Suppositories to Treat Symptomatic Internal Hemorrhoids Anucort-HC, 25 Mg Rectal Suppository, Placebo suppository - Internal Hemorrhoids | Phase 2 | Completed | G & W Laboratories Inc. | 150 | 2013-10-01 | 2016-11-03 |
| Budesonide vs. Mesalazine vs. Budesonide/Mesalazine Suppository Combination Therapy in Acute Ulcerative Proctitis Budesonide 2 mg suppository, Budesonide 4 mg suppository, Mesalazine 1 g suppository - Proctitis | Phase 2 | Completed | Dr. Falk Pharma GmbH | 320 | 2013-09-01 | 2019-05-07 |
| Effects of Perioperative B&O Suppositories on Post-op Pain and Morphine Use After Laparoscopic Prostatectomy belladonna 16.2 mg and opium 60 mg suppository - Pain | Not applicable | Completed | Benaroya Research Institute | 135 | 2008-10-01 | 2019-04-23 |
| Lyophilized Black Raspberries in Adults With Familial Adenomatous Polyposis (FAP) Black raspberry (BRB) Slurry, Black Raspberry (BRB) Suppositories, Black Raspberry (BRB) Placebo Slurry - Familial Adenomatous Polyposis | Phase 1 | Completed | The Cleveland Clinic | 34 | 2005-12-01 | 2016-02-15 |
| New Tablet Formulation and Dosing Regimen of Balsalazide Disodium in Mildly to Moderately Active Ulcerative Colitis 5 ASA, enemas, suppositories, corticosteroids - Ulcerative Colitis | Phase 3 | Completed | Bausch Health Americas, Inc. | 225 | 2005-12-01 | 2019-11-25 |
Showing 20 of 21. Sign in to see all of them.
Pain (2) · Abortion, Incomplete (1) · Abortion, Missed (1) · Abortion, Spontaneous (1) · Adenomatous Polyposis Coli (1) · Agnosia (1) · Candidiasis, Vulvovaginal (1) · Colitis, Ulcerative (1) · Colorectal Neoplasms (1) · Constipation (1) · Delirium (1) · Dementia (1) · Encopresis (1) · Infertility (1) · Infertility, Female (1)
Alexandria University (1) · Avva Rus, JSC (1) · Aziende Chimiche Riunite Angelini Francesco S.p.A (1) · Balikesir University (1) · Bausch Health Americas, Inc. (1) · Benaroya Research Institute (1) · Cairo University (1) · Clinical Research Centre, Malaysia (1) · Dr. Falk Pharma GmbH (1) · Dr. John A. Thiel Medical Professional Corporation (1) · G & W Laboratories Inc. (1) · Lewai Sharki Abdulaziz, MSc PhD (1) · Mayo Clinic (1) · National University of Malaysia (1) · Nivagen Pharmaceuticals Inc. (1)
United States (7) · Egypt (2) · Australia (1) · Germany (1) · India (1) · Iraq (1) · Israel (1) · Malaysia (1) · Russia (1) · South Korea (1) · Switzerland (1) · United Kingdom (1)
Allan G Coates, DO (1) · Anand Shukla, MS, MBA, (1) · Britta Siegmund, Professor (1) · Carol A Burke, MD (1) · Erik Garpestad, MD (1) · Faris A Khazaal, FRCP (1) · John H Scholefield, MD (1) · John M Corman, MD (1) · Jonathan Leung, PharmD, RPh (1) · Lewai S Abdulaziz, MSc PhD (1) · Milko Radicioni, MD (1) · Mohammed A Al-Kurtas, FICMS.Path (1) · Rahana Abd Rahman (1) · Riyadh M Hasan, CABS (1)
PMID 10352050, PMID 12917995, PMID 15507941, PMID 17196714, PMID 23440827, PMID 29702300, PMID 32410819, PMID 39979898