4 recruiting, 1 withdrawn. 3 Early Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 3 | Recruiting 2, Withdrawn 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow IIM: new trials by email Literature Review of IIM trials Research Report on IIM
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases. RD06-05 CART Cell Injection - SLE, LN | Early Phase 1 | Recruiting | Nanjing Bioheng Biotech Co., Ltd. | 96 | 2025-07-24 | 2026-08-03 |
| AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases. Allogeneic NK Cells - Refractory Rheumatoid Arthritis (RA), Idiopathic Inflammatory Myopathies (IIMs) | Phase 2 | Recruiting | Artiva Biotherapeutics, Inc. | 90 | 2025-07-09 | 2026-07-31 |
| MIHRA - Patient-Rooted Insights for Shaping Myositis Science (PRISMS) No intervention - qualitative and mixed methods investigations - IBM, IIM | Recruiting | Myositis International Health & Research Collaborative Alliance Foundation | 700 | 2025-06-25 | 2026-01-28 | |
| Clinical Study on Targeted CD19/BCMA CAR-T Therapy for Autoimmune Diseases RD06-05 CART Cell Injection - SLE, Systemic Sclerosis | Early Phase 1 | Recruiting | Nanjing Bioheng Biotech Co., Ltd. | 18 | 2025-01-03 | 2026-02-02 |
| A Study of RD06-04 in Patients With Active Autoimmune Diseases RD06-04 cell infusion - SLE, Sclerosis | Early Phase 1 | Withdrawn | Nanjing Bioheng Biotech Co., Ltd. | 2024-08-31 | 2026-02-03 |
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (3) · Myositis (2) · Scleroderma, Systemic (2) · Anti-Glomerular Basement Membrane Disease (1) · Arthritis, Rheumatoid (1) · Dermatomyositis (1) · Glomerulonephritis, IGA (1) · Myositis, Inclusion Body (1) · Neuromyelitis Optica (1) · Patient Participation (1) · Polymyositis (1) · Rare Diseases (1) · Scleroderma, Diffuse (1) · Sclerosis (1) · Sjogren's Syndrome (1)
Skin Diseases (5) · Skin and Connective Tissue Diseases (5) · Autoimmune Diseases (4) · Immune System Diseases (4) · Cardiovascular Diseases (3) · Connective Tissue Diseases (3) · Nervous System Diseases (3) · Skin Diseases, Vascular (3) · Systemic Vasculitis (3) · Vascular Diseases (3) · Vasculitis (3) · Eye Diseases (2) · Muscular Diseases (2) · Musculoskeletal Diseases (2) · Neuromuscular Diseases (2)
Nanjing Bioheng Biotech Co., Ltd. (3) · Artiva Biotherapeutics, Inc. (1) · Myositis International Health & Research Collaborative Alliance Foundation (1)
China (3) · United States (2) · Brazil (1) · Bulgaria (1) · France (1) · Germany (1) · Italy (1) · Poland (1) · Portugal (1) · Romania (1) · Serbia (1) · Spain (1)
Lesley Ann Saketkoo, MD, MPH (1) · Michael Saddekni, M.D., PgDip, BCMAS (1)