Hypersensitivity: Clinical Trials

39 recruiting. 39 Phase 4.

By phase and status

Phase	Trials	Status
Phase 4	39	Recruiting 39

Follow Hypersensitivity: new trials by email Literature Review of Hypersensitivity trials Research Report on Hypersensitivity

Trials (filtered) newest first · largest first

All 39 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Oral Food Challenge After One to Two Doses of Omalizumab Treatment for Food Allergy Omalizumab - Food Allergy	Phase 4	Recruiting	Johns Hopkins University	20	2026-10-19	2026-10-28
Safety and Effectiveness of Sebetralstat (KVD900) for Short-Term Prophylaxis Before Procedures in People With Hereditary Angioedema (KONTROL) KVD900 600 mg - Hereditary Angioedema	Phase 4	Recruiting	KalVista Pharmaceuticals, Ltd.	100	2026-08-17	2026-09-17
The Impact of Dietary Salt on the Severity of Eczema Sodium chloride tablets, Placebo Tablets - Eczema, Atopic Dermatitis	Phase 4	Recruiting	University of California, San Francisco	40	2026-08-10	2026-09-10
Evaluation of ALLERgen Specific Vaccination of DOG Allergic Patients in Swedish Practice ALK Alutard SQ Dog - Allergic Rhinitis, Asthma (Diagnosis)	Phase 4	Recruiting	Karolinska Institutet	40	2026-08-01	2026-06-29
Giving Asthmatics Intramuscular Steroids for Preventing Return to the Emergency Department Dexamethasone 16mg IM, Prednisone 60mg PO - Asthma	Phase 4	Recruiting	Montefiore Medical Center	182	2026-07-23	2026-07-24
Obtaining Descriptive Classifications of Pruritus and Assessing Change in Pruritus Over Time in Atopic Dermatitis Patients Using Topical Roflumilast Cream. Roflumilast Cream 0.15% - ITCH, Atopic Dermatitis	Phase 4	Recruiting	Integrative Skin Science and Research	40	2026-07-21	2026-08-13
The Impact of Salt Intake on Sodium in the Skin and Inflammatory Skin Disease Sodium chloride tablets, Placebo Tablets - Atopic Dermatitis (Eczema), Psoriasis	Phase 4	Recruiting	University of California, San Francisco	50	2026-07-14	2026-09-09
BETRI-Prospective: Asthma Control in Single Inhaler ICS/LABA/LAMA (87/5/9 pMDI [BDP/FF/GB - 100/6/12.5 μg]) vs Single Inhaler ICS/LABA (200/6 pMDI [BDP/FF - 200/6 μg]) Beclometasone dipropionate, formoterol fumarate, and glycopyrronium bromide (100/6/12.5 µg per actuation), Foster® 200/6 pMDI (BDP/FF-200/6 µg) - Asthma	Phase 4	Recruiting	Chiesi Farmaceutici S.p.A.	644	2026-06-28	2026-07-31
Tezepelumab in the Treatment of Emergency Room Asthma in Adults (TERAA) Tezepelumab, Placebo - Severe Asthma	Phase 4	Recruiting	University of Alberta	100	2026-05-11	2026-07-17
Ventilation and Perfusion in Asthmatics Albuterol Sulfate, Albuterol-Budesonide - Asthma	Phase 4	Recruiting	University of Miami	40	2026-04-27	2026-10-23
Steroid Use in Treatment of Allergic Reactions to Food Antihistamines, Systemic corticosteroids, Adrenaline (rescue medication) - Anaphylactic Reaction, Anaphylaxis	Phase 4	Recruiting	Johannes Trueck	160	2026-01-26	2026-01-27
CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma Implementation bundle - Moderate to Severe Asthma	Phase 4	Recruiting	Washington University School of Medicine	2000	2026-01-06	2026-09-10
Withdrawal of Dupilumab in Severe Asthma Stopping dupilumab - Severe Asthma	Phase 4	Recruiting	University Hospital, Toulouse	205	2025-12-15	2026-10-08
Pasteurised Donor Human Milk Supplementation for Term Babies Standard care Cow's milk based formula, Dietary Supplement: PDHM Pasteurised Donor Human Milk - Neonatal Hypoglycemia, Metabolic Complication	Phase 4	Recruiting	The University of Queensland	1444	2025-12-04	2026-09-02
Jack Jumper Ant Venom Immunotherapy Long-term Effectiveness Investigation Jack Jumper Ant Venom Immunotherapy - Allergy, Immunotherapy	Phase 4	Recruiting	Murdoch Childrens Research Institute	100	2025-11-25	2026-10-02
45th Multicenter Airway Research Collaboration Airsupra - Asthma Acute, Asthma Exacerbation	Phase 4	Recruiting	Massachusetts General Hospital	1860	2025-11-07	2026-04-17
Individualizing Treatment for Asthma in Primary Care (Full Study) Inhaled corticosteroid (ICS), Azithromycin, Asthma Symptom Monitoring Web-based Application - Asthma, Asthma Attack	Phase 4	Recruiting	DARTNet Institute	3200	2025-08-01	2025-10-29
Therapeutic Relevance of Abnormal Airway Morphology in Asthma Inhaled corticosteroid (ICS), Oral Corticosteroid (OCS) - Asthma	Phase 4	Recruiting	McMaster University	242	2025-06-02	2025-09-11
Study Evaluating the Safety and Efficacy of Neffy or Intramuscular Adrenalin in Patients With Allergic Reactions After Oral Food Challenge or Allergen Immunotherapy Neffy, Adrenaline - Allergic Reactions	Phase 4	Recruiting	ARS Pharmaceuticals, Inc.	600	2025-05-20	2026-04-21
Which of the Commonly Available and Approved Drugs in Addition to Standard of Care Can Significantly Improve the Slope of Estimated Glomerular Filtration Rate at Two Years When Compared to Standard of Care Alone in South-Asian Kidney Biopsy-proven Adult (≥18 Years) Primary IgA Nephropathy? Oral prednisolone and SoC, Gut-directed budesonide and SoC, Mycophenolate mofetil (MMF) and SoC - IgA Nephropathy, Renal Insufficiency, Chronic	Phase 4	Recruiting	Christian Medical College, Vellore, India	585	2025-02-15	2025-07-14

Showing 20 of 39. Sign in to see all of them.

Narrower conditions

Asthma (17)  ·  Dermatitis, Atopic (7)  ·  Eczema (4)  ·  Food Hypersensitivity (3)  ·  Inflammation (3)  ·  Sarcoidosis (2)  ·  Sarcoidosis, Pulmonary (2)  ·  Anaphylaxis (1)  ·  Angioedema (1)  ·  Angioedemas, Hereditary (1)  ·  Breast Feeding (1)  ·  Chronic Urticaria (1)  ·  Deglutition Disorders (1)  ·  Disease (1)

Broader conditions

Immune System Diseases (39)  ·  Hypersensitivity, Immediate (33)  ·  Respiratory Tract Diseases (20)  ·  Lung Diseases (19)  ·  Bronchial Diseases (17)  ·  Lung Diseases, Obstructive (17)  ·  Respiratory Hypersensitivity (17)  ·  Skin Diseases (12)  ·  Skin and Connective Tissue Diseases (12)  ·  Congenital, Hereditary, and Neonatal Diseases and Abnormalities (8)  ·  Dermatitis (8)  ·  Genetic Diseases, Inborn (8)  ·  Pathological Conditions, Signs and Symptoms (8)  ·  Skin Diseases, Eczematous (8)

Interventions

dupilumab (7)  ·  Omalizumab (3)  ·  Beclomethasone (2)  ·  Epinephrine (2)  ·  Formoterol Fumarate (2)  ·  Hydroxychloroquine (2)  ·  Prednisolone (2)  ·  Prednisone (2)  ·  Sodium Chloride (2)  ·  Adrenal Cortex Hormones (1)  ·  Albuterol (1)  ·  Angiotensin Receptor Antagonists (1)  ·  Azithromycin (1)  ·  Betamethasone (1)  ·  Budesonide (1)

Sponsors

University of California, San Francisco (3)  ·  University of California, San Diego (2)  ·  ARS Pharmaceuticals, Inc. (1)  ·  Assistance Publique - Hôpitaux de Paris (1)  ·  Bernstein Clinical Research Center (1)  ·  Chiesi Farmaceutici S.p.A. (1)  ·  Christian Medical College, Vellore, India (1)  ·  DARTNet Institute (1)  ·  Gelb, Arthur F., M.D. (1)  ·  Hospices Civils de Lyon (1)  ·  Integrative Skin Science and Research (1)  ·  Johannes Trueck (1)  ·  Johns Hopkins University (1)  ·  KalVista Pharmaceuticals, Ltd. (1)  ·  Karolinska Institutet (1)

Countries

United States (23)  ·  France (4)  ·  Australia (2)  ·  Canada (2)  ·  India (2)  ·  Sweden (2)  ·  Switzerland (2)  ·  Bulgaria (1)  ·  Denmark (1)  ·  Finland (1)  ·  Norway (1)

Top investigators

Katrina Abuabara, MD (2)  ·  Adriana Le, MBBS FRACP (1)  ·  Amy Paller, MD (1)  ·  Arthur F Gelb, MD (1)  ·  Carlo Lutz, MD (1)  ·  Connie Hsia, MD (1)  ·  Dave Mauger, PhD (1)  ·  George T John, DM, FRCP, FRACP (1)  ·  Irvin Mayers, MD (1)  ·  Jeffrey Cheng, MD, PhD (1)  ·  Jennifer Koplin, PhD (1)  ·  Johann Gudjonsson, MD (1)  ·  Jonathan Barratt, PhD, FRCP (1)

Results publications

PMID 10109801, PMID 15225842, PMID 15823451, PMID 16226443, PMID 16478839, PMID 21893215, PMID 22560478, PMID 23537051, PMID 23932460, PMID 24157819, PMID 24290280, PMID 24753153, PMID 25950858, PMID 26337607, PMID 26343939, PMID 26717511, PMID 27053725, PMID 28500390, PMID 30185520, PMID 31613151, PMID 32729038, PMID 34779751, PMID 37914234, PMID 39762098, PMID 40738645

NIH funding

2025 (2), K23HL171940 (1), R01HL161362 (1)