34 completed, 10 unknown, 7 recruiting, 6 terminated. 20 Phase 2, 15 Not applicable, 7 Phase 4, 6 Phase 1, 6 Phase 3.
Follow Sarcoidosis, Pulmonary: new trials by email Literature Review of Sarcoidosis, Pulmonary trials Research Report on Sarcoidosis, Pulmonary
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Trial of Tulisokibart (MK-7240) in Participants With Pulmonary Sarcoidosis (MK-7240-016) Tulisokibart, Placebo, Background prednisone therapy - Pulmonary Sarcoidosis | Phase 2 | Not yet recruiting | Merck Sharp & Dohme LLC | 158 | 2026-11-06 | 2026-10-09 |
| Evaluation of the Efficacy and Safety of Compound Betamethasone in Pulmonary Sarcoidosis Prednisone, Compound betamethasone - Sarcoidosis, Pulmonary | Phase 2 / Phase 3 | Not yet recruiting | Peking Union Medical College Hospital | 126 | 2026-11-01 | 2026-10-15 |
| An Efficacy Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis With or Without Extrapulmonary Manifestations XTMAB-16, Placebo - Pulmonary Sarcoidosis | Phase 2 | Not yet recruiting | Xentria, Inc. | 182 | 2026-10-30 | 2026-10-21 |
| A Comparison of a Medication Adherence Platform (FORTISKAP™) vs. Usual Care in Subjects on Oral Medications for the Treatment of Interstitial Lung Disease, Sarcoid and Pulmonary Hypertension Idiopathic Pulmonary Fibrosis (IPF), Sarcoidosis Lung | Not yet recruiting | Cosmos Rx, Inc | 100 | 2026-07-01 | 2026-05-29 | |
| Diagnostic Value of EBUS-Guided Transbronchial Mediastinal Cryobiopsy Versus Conventional Bronchoscopic Approaches for Stage I/II Sarcoidosis EBUS-TBNA-based sampling methods, EBUS-TBMC based sampling method - Sarcoidosis, Pulmonary | Not applicable | Active not recruiting | China-Japan Friendship Hospital | 469 | 2026-03-01 | 2026-08-06 |
| Investigation of the Efficacy of Metformin Therapy on Pulmonary Sarcoidosis Metformin, Cellulose - Sarcoidosis, Pulmonary | Phase 2 | Withdrawn | University of Maryland, Baltimore | 2025-12-10 | 2025-02-11 | |
| Sarcoidosis Immunotsuppressive Therapy and Lymphoma Development lymph node biopsy - Sarcoidosis Lung | Completed | Alexandria University | 40 | 2025-08-01 | 2026-01-15 | |
| Hydroxychloroquine as a Steroid-sparing Agent in Extrapulmonary Sarcoidosis Hydroxychloroquine, Placebo - Sarcoidosis, Pulmonary | Phase 4 | Recruiting | Hospices Civils de Lyon | 140 | 2024-07-30 | 2026-09-17 |
| RCT of Nintedanib in Fibrotic Sarcoidosis Nintedanib, Standard of care - Sarcoidosis, Pulmonary | Phase 4 | Recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 120 | 2024-06-30 | 2024-10-23 |
| Efficacy and Safety Study of OATD-01 in Patients With Active Pulmonary Sarcoidosis OATD-01, Placebo - Pulmonary Sarcoidosis | Phase 2 | Recruiting | Molecure S.A. | 96 | 2024-03-21 | 2026-10-08 |
| An Open-label Extension Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis XTMAB-16 - Pulmonary Sarcoidosis | Phase 2 | Completed | Xentria, Inc. | 31 | 2024-03-01 | 2026-10-16 |
| Feasibility of Semaglutide in Advanced Lung Disease Semaglutide Pen Injector - Obesity, Interstitial Lung Disease | Phase 1 / Phase 2 | Recruiting | University of Pennsylvania | 8 | 2024-01-29 | 2026-04-21 |
| Comparative Diagnostic Yield of Endobronchial Cryo Biopsy vs Forceps Biopsy in Patients With Suspected Sarcoidosis Cryobiopsy with liquid nitrogen, Endobronchial Forceps Biopsy - Sarcoidosis Lung, Pulmonary Sarcoidosis | Not applicable | Recruiting | Sanjay Gandhi Postgraduate Institute of Medical Sciences | 150 | 2024-01-01 | 2025-03-03 |
| Study of Multiple-Ascending-Dose Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis With or Without Extrapulmonary Manifestations XTMAB-16 or Placebo - Pulmonary Sarcoidosis | Phase 1 / Phase 2 | Active not recruiting | Xentria, Inc. | 32 | 2023-11-10 | 2026-10-02 |
| Study Comparing Chronic Beryllium Disease to Pulmonary Sarcoidosis Pulmonary Sarcoidosis, Chronic Beryllium Disease | Unknown | Assistance Publique - Hôpitaux de Paris | 200 | 2023-06-14 | 2023-11-02 | |
| Comparison of Different Exercise Training on Exercise Capacity and Fatigue in Patients With Sarcoidosis Exercise- One-Legged, Exercise-Two-Legged - Pulmonary Sarcoidosis | Not applicable | Completed | Istanbul University - Cerrahpasa | 26 | 2023-03-01 | 2024-10-15 |
| the PHENOSAR Trial: Use of Antibiotics in Treatment of Sarcoidosis FDG-PET/CT - Sarcoidosis, Pulmonary, Sarcoidosis Skin | Not applicable | Active not recruiting | St. Antonius Hospital | 40 | 2023-02-15 | 2026-02-12 |
| Risk Indicators of Sarcoidosis Evolution-Unified Protocol Sarcoidosis, Pulmonary | Recruiting | University of California, San Francisco | 200 | 2023-01-10 | 2026-01-08 | |
| Peripheral Airway Biopsy in Sarcoidosis Bronchoscopy with airway biopsy - Sarcoidosis, Pulmonary | Not applicable | Completed | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 79 | 2022-10-20 | 2024-04-05 |
| Efficacy and Safety of Intravenous Efzofitimod in Patients With Pulmonary Sarcoidosis Efzofitimod 3 mg/kg, Efzofitimod 5 mg/kg, Placebo - Pulmonary Sarcoidosis | Phase 3 | Completed | aTyr Pharma, Inc. | 268 | 2022-09-15 | 2026-06-04 |
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Sarcoidosis (33) · Lung Diseases, Interstitial (8) · Granuloma (4) · Pulmonary Fibrosis (4) · Hypertension, Pulmonary (3) · Inflammation (3) · Asthma (2) · Idiopathic Pulmonary Fibrosis (2) · Lung Diseases (2) · Lymphoproliferative Disorders (2) · Motor Activity (2) · Pulmonary Disease, Chronic Obstructive (2) · alpha 1-Antitrypsin Deficiency (2) · Arthritis, Rheumatoid (1)
Hemic and Lymphatic Diseases (66) · Hypersensitivity (66) · Hypersensitivity, Delayed (66) · Immune System Diseases (66) · Lymphatic Diseases (66) · Respiratory Tract Diseases (66) · Lung Diseases (64) · Lymphoproliferative Disorders (64) · Lung Diseases, Interstitial (58) · Sarcoidosis (33) · Pathological Conditions, Signs and Symptoms (11) · Pathologic Processes (10) · Cardiovascular Diseases (4) · Fibrosis (4) · Vascular Diseases (4)
Prednisone (5) · Hydroxychloroquine (3) · Azithromycin (2) · Prednisolone (2) · 68Ga-DOTANOC (1) · Acetylcysteine (1) · Adrenal Cortex Hormones (1) · Adrenocorticotropic Hormone (1) · Atorvastatin (1) · Blood Specimen Collection (1) · Bronchoalveolar Lavage (1) · Bronchoscopy (1) · Cellulose (1) · Clinical Laboratory Techniques (1) · Clinical Trials as Topic (1)
National Heart, Lung, and Blood Institute (NHLBI) (3) · Post Graduate Institute of Medical Education and Research, Chandigarh (3) · University of Cincinnati (3) · Xentria, Inc. (3) · Assistance Publique - Hôpitaux de Paris (2) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (2) · Istanbul University - Cerrahpasa (2) · National Jewish Health (2) · Novartis Pharmaceuticals (2) · Turku University Hospital (2) · aTyr Pharma, Inc. (2) · Aarhus University Hospital (1) · Alexandria University (1) · Bellerophon (1) · Celgene (1)
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Robert P Baughman, MD (3) · Ajmal Khan, MBBS, MD, DM (1) · Alberto Pesci (1) · Amirsoheil Talebian, MD (1) · Anne Roivainen, Professor (1) · Ashutosh N Aggarwal, MD, DM (1) · Dariusz Stencel, MD (1) · Don C Rockey, MD (1)
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