2 recruiting, 1 completed. 3 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 3 | Recruiting 2, Completed 1 |
Follow High Grade Gliomas: new trials by email Literature Review of High Grade Gliomas trials Research Report on High Grade Gliomas
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG) Nivolumab, Nivolumab-IRDye800 - Brain Cancer, HGG | Early Phase 1 | Recruiting | Eben Rosenthal | 38 | 2026-03-27 | 2026-07-01 |
| A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies. SGT-53, hypofractionated radiotherapy with immunotherapy, Nivolumab - CNS Malignancies, Medulloblastoma Recurrent | Early Phase 1 | Recruiting | Children's National Research Institute | 18 | 2025-12-16 | 2026-04-29 |
| Exploratory, Phase 0 Study of Positron Emission Tomography (PET) Imaging Agent, F-18 RGD-K5 F-18 RGD-K5 - Sarcoma, Melanoma | Early Phase 1 | Completed | Siemens Molecular Imaging | 16 | 2008-08-01 | 2009-02-02 |
Astrocytoma (1) · Brain Neoplasms (1) · Breast Neoplasms (1) · Central Nervous System Neoplasms (1) · Glioblastoma (1) · Glioma (1) · Laryngeal Diseases (1) · Lung Neoplasms (1) · Melanoma (1) · Neoplasms, Germ Cell and Embryonal (1) · Oligodendroglioma (1) · Pinealoma (1) · Sarcoma (1)
Neoplasms (3) · Neoplasms by Histologic Type (3) · Neoplasms by Site (3) · Neoplasms, Glandular and Epithelial (3) · Neoplasms, Nerve Tissue (3) · Neoplasms, Neuroepithelial (3) · Neuroectodermal Tumors (3) · Brain Diseases (2) · Central Nervous System Diseases (2) · Neoplasms, Germ Cell and Embryonal (2) · Nervous System Diseases (2) · Nervous System Neoplasms (2) · Brain Neoplasms (1) · Breast Diseases (1) · Central Nervous System Neoplasms (1)
Nivolumab (2) · Immunotherapy (1)
Children's National Research Institute (1) · Eben Rosenthal (1) · Siemens Molecular Imaging (1)
United States (3)
Michael Yu, MD (1) · Patrick Kelly, MD (1)